Stable episomal expression system under control of a stress inducible promoter enhances the immunogenicity of Bacillus subtilis as a vector for antigen delivery

Vaccine

Volumn 24, Issue 15, 2006, Pages 2935-2943

  Paccez, Juliano D ^a   Luiz, Wilson B ^a   Sbrogio Almeida, Maria E ^b   Ferreira, Rita C C ^a   Schumann, Wolfgang ^c   Ferreira, Luís C S ^a,d  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b INSTITUTO BUTANTAN   (Brazil)

^c UNIVERSITY OF BAYREUTH   (Germany)

^d NONE   (Brazil)

Author keywords

B. subtilis spores; B. subtilis vaccine vectors; ETEC; gsiB; LT; Oral vaccines

Indexed keywords

IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; LABILE TOXIN B ANTIBODY; TOXIN ANTIBODY; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIBODY RESPONSE; ANTIGEN EXPRESSION; ARTICLE; BACILLUS SUBTILIS; DRUG ACTIVITY; DRUG MECHANISM; ENTEROTOXIGENIC ESCHERICHIA COLI; EPISOME; GENE EXPRESSION; GLUCOSE STARVATION INDUCIBLE GENE; HEAT TOLERANCE; HETEROLOGOUS EXPRESSION; IMMUNIZATION; IMMUNOGENICITY; IMMUNOGLOBULIN BLOOD LEVEL; MOLECULAR CLONING; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; RECEPTOR BINDING; RECOMBINANT PLASMID; SHUTTLE VECTOR; STRESS;

ADMINISTRATION, ORAL; ANIMALS; ANTIBODIES, BACTERIAL; BACILLUS SUBTILIS; BACTERIAL PROTEINS; BACTERIAL TOXINS; BACTERIAL VACCINES; ENTEROTOXINS; ENZYME-LINKED IMMUNOSORBENT ASSAY; ESCHERICHIA COLI PROTEINS; FECES; FEMALE; GENE EXPRESSION REGULATION, BACTERIAL; GENETIC VECTORS; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; INJECTIONS, INTRAPERITONEAL; MICE; MICE, INBRED C57BL; PLASMIDS; PROMOTER REGIONS (GENETICS); VACCINES, SYNTHETIC;

EID: 33644929499     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2005.12.013     Document Type: Article

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