The pharmacokinetic and pharmacodynamic consequences of the co-administration of lamotrigine and a combined oral contraceptive in healthy female subjects

British Journal of Clinical Pharmacology

Volumn 61, Issue 2, 2006, Pages 191-199

  Sidhu, Jagdev ^a   Job, Sarah ^a   Singh, Sunita ^a   Philipson, Richard ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

Author keywords

Combined oral contraceptive; Interaction; Lamotrigine; Pharmacodynamics; Pharmacokinetics

Indexed keywords

ESTRADIOL; ETHINYLESTRADIOL PLUS LEVONORGESTREL; FOLLITROPIN; LAMOTRIGINE; LUTEINIZING HORMONE; ORAL CONTRACEPTIVE AGENT; PROGESTERONE; SEX HORMONE BINDING GLOBULIN;

ADULT; AREA UNDER THE CURVE; ARTICLE; ATAXIA; BREAKTHROUGH BLEEDING; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIZZINESS; DOSE CALCULATION; DOSE TIME EFFECT RELATION; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG DOSE REDUCTION; DRUG EFFECT; DRUG INDUCED DISEASE; DRUG WITHDRAWAL; ESTRADIOL BLOOD LEVEL; FEMALE; FOLLITROPIN BLOOD LEVEL; HORMONE BLOOD LEVEL; HUMAN; LUTEINIZING HORMONE BLOOD LEVEL; MAXIMUM ALLOWABLE CONCENTRATION; MEDICAL ASSESSMENT; MONOTHERAPY; NAUSEA; NEUROLOGIC DISEASE; NORMAL HUMAN; ORAL CONTRACEPTION; OVULATION INHIBITION; PRIORITY JOURNAL; PROGESTERONE BLOOD LEVEL; VISUAL HALLUCINATION;

ADOLESCENT; ADULT; ANTICONVULSANTS; CONTRACEPTIVES, ORAL, COMBINED; DRUG INTERACTIONS; ESTRADIOL; ETHINYL ESTRADIOL; FEMALE; FOLLICLE STIMULATING HORMONE; HUMANS; LEVONORGESTREL; LUTEINIZING HORMONE; MIDDLE AGED; OVULATION; SEX HORMONE-BINDING GLOBULIN; TRIAZINES;

EID: 33644904320     PISSN: 03065251     EISSN: 13652125     Source Type: Journal    
DOI: 10.1111/j.1365-2125.2005.02539.x     Document Type: Article

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