Changes in the minimum alveolar concentration of isoflurane and some cardiopulmonary measurements during three continuous infusion rates of dexmedetomidine in dogs

Veterinary Anaesthesia and Analgesia

Volumn 33, Issue 2, 2006, Pages 97-103

  Pascoe, Peter J ^a   Raekallio, Marja ^b   Kuusela, Erja ^b   McKusick, Brett ^c   Granholm, Mikael ^c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF HELSINKI   (Finland)

^c ORION CORPORATION   (Finland)

Author keywords

Dexmedetomidine; Heart rate; Isoflurane; Minimum alveolar concentration

Indexed keywords

ANIMALIA; CANIS FAMILIARIS;

EID: 33644903487     PISSN: 14672987     EISSN: 14672995     Source Type: Journal    
DOI: 10.1111/j.1467-2995.2005.00236.x     Document Type: Article

References (28)

1. Aantaa R Jaakola ML Kallio A et al. 1997 Reduction of the minimum alveolar concentration of isoflurane by dexmedetomidine Anesthesiology 86 1055 1060
2. Aho M Lehtinen AM Erkola O et al. 1991 The effect of intravenously administered dexmedetomidine on perioperative hemodynamics and isoflurane requirements in patients undergoing abdominal hysterectomy Anesthesiology 74 997 1002
3. Bloor BC Flacke WE 1982 Reduction in halothane anesthetic requirement by clonidine, an alpha-adrenergic agonist Anesth Analg 61 741 745
4. Bloor BC Frankland M Alper G et al. 1992 Hemodynamic and sedative effects of dexmedetomidine in dog J Pharmacol Exp Ther 263 690 697
5. Eger EI II. Saidman LJ Brandstater B 1965 Minimum alveolar anesthetic concentration: a standard of anesthetic potency Anesthesiology 26 756 763
6. Ewing KK Mohammed HO Scarlett JM et al. 1993 Reduction of isoflurane anesthetic requirement by medetomidine and its restoration by atipamezole in dogs Am J Vet Res 54 294 299
7. Flacke JW Bloor BC Flacke WE et al. 1987 Reduced narcotic requirement by clonidine with improved hemodynamic and adrenergic stability in patients undergoing coronary bypass surgery Anesthesiology 67 11 19
8. Flacke WE Flacke JW Bloor BC et al. 1993 Effects of dexmedetomidine on systemic and coronary hemodynamics in the anesthetized dog J Cardiothorac Vasc Anesth 7 41 49
9. Fragen RJ Fitzgerald PC 1999 Effect of dexmedetomidine on the minimum alveolar concentration (MAC) of sevoflurane in adults age 55 to 70 years J Clin Anesth 11 466 470
10. Hamm D Turchi P Jochle W 1995 Sedative and analgesic effects of detomidine and romifidine in horses Vet Rec 136 324 327
11. Hellebrekers LJ Sap R 1997 Medetomidine as a premedicant for ketamine, propofol or fentanyl anaesthesia in dogs Vet Rec 140 545 548
12. Kuusela E Raekallio M Anttila M et al. 2000 Clinical effects and pharmacokinetics of medetomidine and its enantiomers in dogs J Vet Pharmacol Ther 23 15 20
13. Lawrence CJ Prinzen FW de Lange S 1996 The effect of dexmedetomidine on nutrient organ blood flow Anesth Analg 83 1160 1165
14. Mangano D 1997 Perioperative sympatholysis. Beneficial effects of the alpha 2-adrenoceptor agonist mivazerol on hemodynamic stability and myocardial ischemia. McSPI-Europe Research Group Anesthesiology 86 346 363
15. Pagel PS Hettrick DA Kersten JR et al. 1998 Dexmedetomidine produces similar alterations in the determinants of left ventricular afterload in conscious dogs before and after the development of pacing-induced cardiomyopathy Anesthesiology 89 741 748
16. Pypendop B Verstegen J 1998 Hemodynamic effects of medetomidine in the dog: a dose titration study Vet Surg 27 612 622
17. Salmenpera MT Szlam F Hug CCJ 1994 Anesthetic and hemodynamic interactions of dexmedetomidine and fentanyl in dogs Anesthesiology 80 837 846
18. Sinclair MD O'Grady M Kerr C et al. 2003 The echocardiographic effects of romifidine in dogs with and without prior or concurrent administration of glycopyrrolate Vet Anaesth Analg 30 239 247
19. Steffey EP Howland D Jr. 1977 Isoflurane potency in the dog and cat Am J Vet Res 38 1833 1836
20. Talke P Chen R Thomas B et al. 2000 The hemodynamic and adrenergic effects of perioperative dexmedetomidine infusion after vascular surgery Anesth Analg 90 834 839
21. Tranquilli WJ Thurmon JC Corbin JE et al. 1984 Halothane-sparing effect of xylazine in dogs and subsequent reversal with tolazoline J Vet Pharmacol Ther 7 23 28
22. Vaisanen M Raekallio M Kuusela E et al. 2002 Evaluation of the perioperative stress response in dogs administered medetomidine or acepromazine as part of the preanesthetic medication Am J Vet Res 63 969 975
23. Valverde A Morey TE Hernandez J et al. 2003 Validation of several types of noxious stimuli for use in determining the minimum alveolar concentration for inhalation anesthetics in dogs and rabbits Am J Vet Res 64 957 962
24. Vickery RG Sheridan BC Segal IS et al. 1988 Anesthetic and hemodynamic effects of the stereoisomers of medetomidine, an alpha 2-adrenergic agonist, in halothane-anesthetized dogs Anesth Analg 67 611 615
25. Vuorilehto L Salonen JS Anttila M 1989 Picogram level determination of medetomidine in dog serum by capillary gas chromatography with negative ion chemical ionization mass spectrometry J Chromatogr 497 282 287
26. Wagner JG 1974 A safe method for rapidly achieving plasma concentration plateaus Clin Pharmacol Ther 16 691 700
27. Weitz JD Foster SD Waugaman WR et al. 1991 Anesthetic and hemodynamic effects of dexmedetomidine during isoflurane anesthesia in a canine model Nurse Anesth 2 19 27
28. Wijeysundera DN Naik JS Beattie WS 2003 Alpha-2 adrenergic agonists to prevent perioperative cardiovascular complications: a meta-analysis Am J Med 114 742 752