메뉴 건너뛰기




Volumn 31, Issue 1, 2006, Pages 9-13

Identification and clone of human Alzheimer's disease related gene nicastrin promoter

Author keywords

Alzheimer's disease; Nicastrin; Promoter

Indexed keywords

DNA FRAGMENT; GAMMA SECRETASE; GENOMIC DNA; LUCIFERASE; NICASTRIN;

EID: 33644896807     PISSN: 16727347     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (3)

References (13)
  • 1
    • 0032568821 scopus 로고    scopus 로고
    • The presenilin 1 protein is a component of a high molecular weight intracellular complex that contains beta-catenin
    • Yu G, Chen F, Levesque G, et al. The presenilin 1 protein is a component of a high molecular weight intracellular complex that contains beta-catenin[J]. J Biol Chem, 1998, 273(26):16470-16475.
    • (1998) J Biol Chem , vol.273 , Issue.26 , pp. 16470-16475
    • Yu, G.1    Chen, F.2    Levesque, G.3
  • 2
    • 0032488995 scopus 로고    scopus 로고
    • The proteolytic fragments of the Alzheimer's disease-associated presenilin-1 form heterodimers and occur as a 100-150 kD molecular mass complex
    • Capell A, Grunberg J, Pesold B, et al. The proteolytic fragments of the Alzheimer's disease-associated presenilin-1 form heterodimers and occur as a 100-150 kD molecular mass complex[J]. J Biol Chem, 1998, 273(6):3205-3211.
    • (1998) J Biol Chem , vol.273 , Issue.6 , pp. 3205-3211
    • Capell, A.1    Grunberg, J.2    Pesold, B.3
  • 3
    • 0343819757 scopus 로고    scopus 로고
    • Presenilin 1 is linked with gamma-secretase activity in the detergent solubilized state
    • Li YM, Lai MT, Xu M, et al. Presenilin 1 is linked with gamma-secretase activity in the detergent solubilized state[J]. Proc Natl Acad Sci USA, 2000, 97(11):6138-6143.
    • (2000) Proc Natl Acad Sci USA , vol.97 , Issue.11 , pp. 6138-6143
    • Li, Y.M.1    Lai, M.T.2    Xu, M.3
  • 4
    • 18444417998 scopus 로고    scopus 로고
    • aph-1 and pen-2 are required for Notch pathway signaling, gamma-secretase cleavage of betaAPP, and presenilin protein accumulation
    • Francis R, McGrath G, Zhang J, et al. aph-1 and pen-2 are required for Notch pathway signaling, gamma-secretase cleavage of betaAPP, and presenilin protein accumulation[J]. Dev Cell, 2002, 3(1):85-97.
    • (2002) Dev Cell , vol.3 , Issue.1 , pp. 85-97
    • Francis, R.1    McGrath, G.2    Zhang, J.3
  • 5
    • 0037154158 scopus 로고    scopus 로고
    • APH-1 is a multipass membrane protein essential for the Notch signaling pathway in Caenorhabditis elegans embryos
    • Goutte C, Tsunozaki M, Hale VA, et al. APH-1 is a multipass membrane protein essential for the Notch signaling pathway in Caenorhabditis elegans embryos[J]. Proc Natl Acad Sci USA, 2002, 99(2):775-779.
    • (2002) Proc Natl Acad Sci USA , vol.99 , Issue.2 , pp. 775-779
    • Goutte, C.1    Tsunozaki, M.2    Hale, V.A.3
  • 6
    • 0038652102 scopus 로고    scopus 로고
    • Gamma-secretase is a membrane protein complex comprised of presenilin, nicastrin, Aph-1, and Pen-2
    • Kimberly WT, LaVoie MJ, Ostaszewski BL, et al. Gamma-secretase is a membrane protein complex comprised of presenilin, nicastrin, Aph-1, and Pen-2[J]. Proc Natl Acad Sci USA, 2003, 100 (11):6382-6387.
    • (2003) Proc Natl Acad Sci USA , vol.100 , Issue.11 , pp. 6382-6387
    • Kimberly, W.T.1    Lavoie, M.J.2    Ostaszewski, B.L.3
  • 7
    • 0037431082 scopus 로고    scopus 로고
    • Aph-1, Pen-2, and Nicastrin with Presenilin generate an active gamma-secretase complex
    • Review
    • De Strooper B. Aph-1, Pen-2, and Nicastrin with Presenilin generate an active gamma-secretase complex[J]. Neuron, 2003, 38 (1):9-12. (Review)
    • (2003) Neuron , vol.38 , Issue.1 , pp. 9-12
    • De Strooper, B.1
  • 8
    • 0034983725 scopus 로고    scopus 로고
    • Nicastrin. A key regulator of presenilin function, is expressed constitutively in human neural cell lines
    • Satoh J, Kuroda Y. Nicastrin. A key regulator of presenilin function, is expressed constitutively in human neural cell lines[J]. Neuropathology, 2001, 21(2):115-122.
    • (2001) Neuropathology , vol.21 , Issue.2 , pp. 115-122
    • Satoh, J.1    Kuroda, Y.2
  • 9
    • 0034618715 scopus 로고    scopus 로고
    • Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and betaAPP processing
    • Yu G, Nishimura M, Arawaka S, et al. Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and betaAPP processing[J]. Nature, 2000, 407(6800):48-54.
    • (2000) Nature , vol.407 , Issue.6800 , pp. 48-54
    • Yu, G.1    Nishimura, M.2    Arawaka, S.3
  • 10
    • 0037087506 scopus 로고    scopus 로고
    • Notch: A membrane-bound transcription factor
    • Kopan R. Notch: a membrane-bound transcription factor[J]. J Cell Sci, 2002, 115(Pt 6):1095-1097.
    • (2002) J Cell Sci , vol.115 , Issue.PART 6 , pp. 1095-1097
    • Kopan, R.1
  • 11
    • 0035824391 scopus 로고    scopus 로고
    • Gamma-secretase cleavage and nuclear localization of ErbB-4 receptor tyrosine kinase
    • Ni CY, Murphy MP, Golde TE, et al. Gamma-secretase cleavage and nuclear localization of ErbB-4 receptor tyrosine kinase[J]. Science, 2001, 294(5549):2179-2181.
    • (2001) Science , vol.294 , Issue.5549 , pp. 2179-2181
    • Ni, C.Y.1    Murphy, M.P.2    Golde, T.E.3
  • 12
    • 0038117200 scopus 로고    scopus 로고
    • Amyloid precursor protein associates with a nicastrin-dependent docking site on the presenilin 1-gamma-secretase complex in cells demonstrated by fluorescence lifetime imaging
    • Berezovska O, Ramdya P, Skoch J, et al. Amyloid precursor protein associates with a nicastrin-dependent docking site on the presenilin 1-gamma-secretase complex in cells demonstrated by fluorescence lifetime imaging[J]. J Neurosci, 2003, 23(11):4560-4566.
    • (2003) J Neurosci , vol.23 , Issue.11 , pp. 4560-4566
    • Berezovska, O.1    Ramdya, P.2    Skoch, J.3
  • 13
    • 0035005101 scopus 로고    scopus 로고
    • New protease inhibitors prevent gamma-secretase-mediated production of Abeta40/42 without affecting Notch cleavage
    • Petit A, Bihel F, Alves da Costa C, et al. New protease inhibitors prevent gamma-secretase-mediated production of Abeta40/42 without affecting Notch cleavage[J]. Nat Cell Biol, 2001, 3(5):507-511.
    • (2001) Nat Cell Biol , vol.3 , Issue.5 , pp. 507-511
    • Petit, A.1    Bihel, F.2    Alves Da Costa, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.