A double-blind, placebo-controlled study of house dust mite immunotherapy in Chinese asthmatic patients

Allergy: European Journal of Allergy and Clinical Immunology

Volumn 61, Issue 2, 2006, Pages 191-197

  Wang, H ^a   Lin, X ^b   Hao, C ^c   Zhang, C ^a   Sun, B ^a   Zheng, J ^a   Chen, P ^b   Sheng, J ^c   Wu, A ^d,e   Zhong, N ^a  

^a GUANGZHOU MEDICAL UNIVERSITY   (China)

^b GENERAL HOSPITAL OF NORTHERN THEATER COMMAND   (China)

^c Suzhou Municipal Hospital   (China)

^d UNIVERSITY OF HONG KONG   (Hong Kong)

^e QUEEN MARY HOSPITAL   (Hong Kong)

Author keywords

Bronchial hyperresponsiveness; Dermatophagoides; Eosinophils; Inhaled corticosteroid

Indexed keywords

ALUTARD DER P; BECLOMETASONE; BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; BUDESONIDE; CORTICOSTEROID; EOSINOPHIL CATIONIC PROTEIN; FLUTICASONE; HOUSE DUST ALLERGEN; IMMUNOGLOBULIN E; PLACEBO; PREDNISOLONE;

ADOLESCENT; ADULT; ALLERGIC ASTHMA; ARTICLE; ASTHMA; BRONCHUS HYPERREACTIVITY; CHILD; CHINESE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE CONTROL; DISEASE SEVERITY; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG USE; EOSINOPHIL COUNT; FEMALE; HUMAN; IMMUNOTHERAPY; MAJOR CLINICAL STUDY; MALE; PEAK EXPIRATORY FLOW; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SCORING SYSTEM; SELF EXAMINATION; SKIN TEST; STATISTICAL SIGNIFICANCE; SYMPTOM; UNSPECIFIED SIDE EFFECT;

EID: 33644892774     PISSN: 01054538     EISSN: 13989995     Source Type: Journal    
DOI: 10.1111/j.1398-9995.2005.00913.x     Document Type: Article

References (19)

1. Bousquet J Michel FB Vignola AM Allergen immunotherapy: therapeutic vaccines for asthma Clin Allergy Immunol 2004 18 511 528
2. Pifferi M Baldini G Marrazzini G Baldini M Ragazzo V Pietrobelli A et al. Benefits of immunotherapy with a standardized Dermatophagoides pteronyssinus extract in asthmatic children: a three-year prospective study Allergy 2002 57 785 790
3. Pichler CE Helbling A Pichler WJ Three years of specific immunotherapy with house-dust-mite extracts in patients with rhinitis and asthma: significant improvement of allergen-specific parameters and of nonspecific bronchial hyperreactivity Allergy 2001 56 301 306
4. Maestrelli P Zanolla L Marcella P Fabbri L Effect of specific immunotherapy added to pharmacologic treatment and allergen avoidance in asthmatic patients allergic to house dust mite J Allergy Clin Immunol 2004 113 643 649
5. Arvidsson MB Lowhagen O Rak S Allergen specific immunotherapy attenuates early and late phase reactions in lower airways of birch pollen asthmatic patients: a double blind placebo-controlled study Allergy 2004 59 74 80
6. Adkinson NF Jr. Eggleston PA Eney D Goldstein EO Schuberth KC Bacon JR et al. A controlled trial of immunotherapy for asthma in allergic children N Engl J Med 1997 336 324 331
7. National Institutes of Health Global initiative for asthma Natl Heart Lung Blood Inst Publ. No. 95-3659 Bethesda, MD, USA NHLBI 1995 6
8. Malling HJ Weeke B Position paper: Immunotherapy. The European Academy of Allergology and Clinical Immunology (EAACI) Allergy 1993 48 Suppl. 14 7 35
9. Haugaard L Dahl R Jacobsen L A controlled dose-response study of immunotherapy with standardized, partially purified extract of house dust mite: clinical efficacy and side effects J Allergy Clin Immunol 1993 91 709 722
10. Abramson MJ Puy RM Weiner JM Allergen immunotherapy for asthma (Cochrane Review) In The Cochrane Library Issue 3 Oxford, UK Update Software 2003 q3
11. Polosa R Li Gotti F Mangano G Paolino G Mastruzzo C Vancheri C et al. Effect of immunotherapy on asthma progression, BHR and sputum eosinophils in allergic rhinitis Allergy 2004 59 1224 1228
12. Polosa R Ciamarra I Mangano G Prosperini G Pistorio MP Vancheri C et al. Bronchial hyperresponsiveness and airway inflammation markers in non-asthmatics with allergic rhinitis Eur Respir J 2000 15 30 35
13. 20 methacholine Am J Respir Crit Care Med 2001 163 1546 1550
14. Alvarez MJ Olaguibel JM Garcia BE Rodriquez A Tabar AI Urbiola E Airway inflammation in asthma and perennial allergic rhinitis: relationship with nonspecific bronchial responsiveness and maximal airway narrowing Allergy 2000 55 355 362
15. Ohashi Y Nakai Y Kakinoki Y Ohno Y Sakamoto H Kato A et al. Effect of immunotherapy on serum levels of eosinophil cationic protein in perennial allergic rhinitis Ann Otol Rhinol Laryngol 1997 106 848 853
16. Bootsma GP Koenderman L Dekhuijzen PN Festen J Lammers JW van Herwaarden CL Effects of fluticasone propionate and beclomethasone dipropionate on parameters of inflammation in peripheral blood of patients with asthma Allergy 1998 53 653 661
17. Malling HJ Methodology and quality of immunotherapy trials Allergy 2004 59 482 484
18. Moller C Dreborg S Ferdousi HA Halken S Host A Jacobsen L et al. Pollen immunotherapy reduces the development of asthma in children with seasonal rhinoconjunctivitis (the PAT-study) J Allergy Clin Immunol 2002 109 251 256
19. Des Roches A Paradis L Menardo JL Bouges S Daures JP Bousquet J Immunotherapy with a standardized Dermatophagoides pteronyssinus extract: VI. Specific immunotherapy prevents the onset of new sensitizations in children J Allergy Clin Immunol 1997 99 450 453