Heritability of an age-dependent categorical phenotype: Cognitive dysfunction

Twin Research and Human Genetics

Volumn 9, Issue 1, 2006, Pages 17-23

  Reynolds, Chandra A ^a   Fiske, Amy ^b   Fratiglioni, Laura ^c   Pedersen, Nancy L ^b,c   Gatz, Margaret ^b,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^c KAROLINSKA INSTITUTE   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

AGED; ARTICLE; BIOMETRY; COGNITION; COGNITIVE DEFECT; CONTROLLED STUDY; DEMENTIA; ENVIRONMENTAL FACTOR; FEMALE; HERITABILITY; HUMAN; MAJOR CLINICAL STUDY; MALE; PHENOTYPE; PREVALENCE; PRIORITY JOURNAL; TWINS;

AGE OF ONSET; AGED; AGED, 80 AND OVER; CHI-SQUARE DISTRIBUTION; COGNITION DISORDERS; DISEASES IN TWINS; ENVIRONMENT; FEMALE; HUMANS; MALE; MODELS, GENETIC; PHENOTYPE; PREVALENCE; PSYCHIATRIC STATUS RATING SCALES; QUANTITATIVE TRAIT, HERITABLE; REGISTRIES; RISK FACTORS; SWEDEN;

EID: 33644891884     PISSN: 18324274     EISSN: None     Source Type: Journal    
DOI: 10.1375/183242706776403055     Document Type: Article

References (15)

1. Bergem, A. L., Engedal, K., & Kringlen, E. (1997). The role of heredity in late-onset Alzheimer disease and vascular dementia: A twin study. Archives of General Psychiatry, 54, 264-270.
2. Blessed, G., Tomlinson, B. E., & Roth, M. (1968). The association between quantitative measures of dementia and of senile change in the cerebral grey matter of elderly subjects. British Journal of Psychiatry, 114, 797-811.
3. Brandt, J., Welsh, K. A., Breitner, J. C., Folstein, M. F., Helms, M., & Christian, J. C. (1993). Hereditary influences on cognitive functioning in older men: A study of 4000 twin pairs. Archives of Neurology, 50, 599-603.
4. Foley, D. L., Neale, M. C., Gardner, C. O., Pickles, A., & Kendler, K. S. (2003). Major depression and associated impairment: Same or different genetic and environmental risk factors? American Journal of Psychiatry, 160, 2128-2133.
5. Gao, S., Hendrie, H. C., Hall, K. S., & Hui, S. (1998). The relationships between age, sex, and the incidence of dementia and Alzheimer disease: A meta-analysis. Archives of General Psychiatry, 55, 809-815.
6. Gatz, M., Fiske, A., Reynolds, C. A., Wetherell, J. L., Johansson, B., & Pedersen, N. L. (2003). Sex differences in genetic risk for dementia. Behavior Genetics, 33, 95-105.
7. Gatz, M., Fratiglioni, L., Johansson, B., Berg, S., Mortimer, J. A., Reynolds, C. A., Fiske, A., & Pedersen, N. L. (2005). Complete ascertainment of dementia in the Swedish Twin Registry: The HARMONY study. Neurobiology of Aging, 26, 439-447.
8. Gatz, M., Pedersen, N. L., Berg, S., Johansson, B., Johansson, K., Mortimer, J. A., Posner, S. F., Viitanen, M., Winblad, B., & Ahlbom, A. (1997). Heritability for Alzheimer's disease: The study of dementia in Swedish twins. The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences, 52, M117-125.
9. Gatz, M., Reynolds, C. A., John, R., Johansson, B., Mortimer, J. A., & Pedersen, N. L. (2002). Telephone screening to identify potential dementia cases in a population-based sample of older adults. International Psychogeriatrics, 14, 273-289.
10. Juva, K., Makela, M., Erkinjuntti, T., Sulkava, R., Ylikoski, R., Valvanne, J., & Tilvis, R. (1997). Functional assessment scales in detecting dementia. Age and Ageing, 26, 393-400
11. Kahn, R. L., Goldfarb, A. I., Pollack, M., & Peck, A. (1961). Factors in selection of psychiatric treatment for institutionalized aged persons. American Journal of Psychiatry, 118, 241-244.
12. Lichtenstein, P., deFaire, U., Floderus, B., Svartengren, M., Svedberg, P., & Pedersen, N. L. (2002). The Swedish Twin Registry: A unique resource for clinical, epidemiological and genetic studies. Journal of Internal Medicine, 252, 184-205.
13. McClearn, G. E., Johansson, B., Berg, S., Pedersen, N. L., Ahern, F., Petrill, S. A., & Plomin, R. (1997). Substantial genetic influence on cognitive abilities in twins 80 or more years old. Science, 276, 1560-1563.
14. Neale, M. C., Boker, S. M., Xie, G., & Maes, H. H. (1999). Mx: Statistical modeling (5th ed.). Richmond, VA: Department of Psychiatry, Medical College of Virginia.
15. Pedersen, N. L., Plomin, R., Nesselroade, J. R., & McClearn, G. E. (1992). A quantitative genetic analysis of cognitive abilities during the second half of the life span. Psychological Science, 3, 346-353.