COX-2 induces IL-11 production in human breast cancer cells

Journal of Surgical Research

Volumn 131, Issue 2, 2006, Pages 267-275

  Singh, Balraj ^a   Berry, Jacob A ^a   Shoher, Angela ^a,b   Lucci, Anthony ^a  

^a UNIVERSITY OF TEXAS   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Bone metastasis; Breast cancer; COX 2; IL 11

Indexed keywords

CELECOXIB; COMPLEMENTARY DNA; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; INTERLEUKIN 11; LUCIFERASE; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; PROSTAGLANDIN E2;

ANIMAL EXPERIMENT; ANIMAL MODEL; BONE METASTASIS; BREAST CANCER; CANCER CELL; CANCER CELL CULTURE; CELL ISOLATION; CONCENTRATION RESPONSE; CONFERENCE PAPER; CONTROLLED STUDY; CYTOKINE PRODUCTION; HUMAN; HUMAN CELL; IMMUNOASSAY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; BONE NEOPLASMS; BREAST NEOPLASMS; CYCLOOXYGENASE 2; FEMALE; HUMANS; IMMUNOASSAY; INTERLEUKIN-11; MICE; MICE, NUDE; NEOPLASM METASTASIS; TRANSFECTION; TUMOR CELLS, CULTURED; UP-REGULATION;

EID: 33644886010     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2005.11.582     Document Type: Conference Paper

References (29)

1. R.A. Gupta, R.N. DuBois Colorectal cancer prevention and treatment by inhibition of cyclooxygenase-2 Nat Rev Cancer 1 2001 11
2. L.R. Howe, K. Subbaramaiah, A.M.C. Brown Cyclooxygenase-2 a target for the prevention and treatment of breast cancer Endocr Related Cancer 8 2001 97
3. B. Singh, A. Lucci Role of cyclooxygenase-2 in breast cancer J Surg Res 108 2002 173
4. R.A. Soslow, A.J. Dannenberg, D. Rush COX-2 is expressed in human pulmonary, colonic, and mammary tumors Cancer 89 2000 2637
5. N. Kundu, Q. Yang, R. Dorsey Increased cyclooxygenase-2 (cox-2) expression and activity in a murine model of metastatic breast cancer Int J Cancer 93 2001 681
6. C.H. Liu, S.-H. Chang, K. Narko Overexpression of cyclooxygenase-2 is sufficient to induce tumorigenesis in transgenic mice J Biol Chem 276 2001 18563
7. A. Ristimaki, A. Sivula, J. Lundin Prognostic significance of elevated cyclooxygenase-2 expression in breast cancer Cancer Res 62 2002 632
8. G. Girasole, G. Passeri, R.L. Jilka Interleukin-11 a new cytokine critical for osteoclast development J Clin Invest 93 1994 1516
9. C. Sotiriou, M. Lacroix, L. Lespagnard Interleukins-6 and -11 expression in primary breast cancer and subsequent development of bone metastases Cancer Lett 169 2001 87
10. Q. Guo, L.H. Wang, K.H. Ruan Role of Val509 in time-dependent inhibition of human prostaglandin H synthase-2 cyclooxygenase activity by isoform-selective agents J Biol Chem 271 1996 19134
11. O.C. Trifan, R.M. Smith, B.D. Thompson Overexpression of cyclooxygenase-2 induces cell cycle arrest. Evidence for a prostaglandin-independent mechanism J Biol Chem 274 1999 34141
12. K. Subbaramaiah, L. Norton, W. Gerald Cyclooxygenase-2 is overexpressed in HER-2/neu-positive breast cancer evidence for involvement of AP-1 and PEA3 J Biol Chem 277 2002 18649
13. F. Arguello, R.B. Baggs, C.N. Frantz A murine model of experimental metastasis to bone and bone marrow Cancer Res 48 1988 6876
14. Y. Kang, P.M. Siegel, W. Shu A multigenic program mediating breast cancer metastasis to bone Cancer Cell 3 2003 537
15. E.M. Gilhooly, D.P. Rose The association between a mutated ras gene and cyclooxygenase-2 gene expression in human breast cancer cell lines Int J Oncol 15 1999 267
16. C. Sotiriou, M. Lacroix, L. Lagneaux The aspirin metabolite salicylate inhibits breast cancer cells growth and their synthesis of the osteolytic cytokines interleukins-6 and -11 Anticancer Res 19 1999 2997
17. J.F. Harms, D.R. Welch MDA-MB-435 human breast carcinoma metastasis to bone Clin Exp Metastasis 20 2003 327
18. M. Lacroix, B. Siwek, P.J. Marie Production and regulation of interleukin-11 by breast cancer cells Cancer Lett 127 1998 29
19. M.B. Crichton, J.E. Nichols, Y. Zhao Expression of transcripts of interleukin-6 and related cytokines by human breast tumors, breast cancer cells, and adipose stromal cells Mol Cell Endocrinol 118 1996 215
20. O. Kudo, A. Sabokbar, A. Pocock Interleukin-6 and interleukin-11 support human osteoclast formation by a RANKL-independent mechanism Bone 32 2003 1
21. H. Morgan, A. Tumber, P.A. Hill Breast cancer cells induce osteoclast formation by stimulating host IL-11 production and downregulating granulocyte/macrophage colony-stimulating factor Int J Cancer 109 2004 653
22. C. Han, A.J. Demetris, Y. Liu Transforming growth factor-beta (TGF-beta) activates cytosolic phospholipase A2alpha (cPLA2alpha)-mediated prostaglandin E2 (PGE)2/EP1 and peroxisome proliferator-activated receptor-gamma (PPAR-gamma)/Smad signaling pathways in human liver cancer cells. A novel mechanism for subversion of TGF-beta-induced mitoinhibition J Biol Chem 279 2004 44344
23. Y. Zhao, V.R. Agarwal, C.R. Mendelson Transcriptional regulation of CYP19 gene (aromatase) expression in adipose stromal cells in primary culture J Steroid Biochem Mol Biol 61 1997 203
24. Y.G. Crawford, M.L. Gauthier, A. Joubel Histologically normal human mammary epithelia with silenced p16(INK4a) overexpress COX-2, promoting a premalignant program Cancer Cell 5 2004 263
25. V. Bitko, A. Velazquez, L. Yang Transcriptional induction of multiple cytokines by human respiratory syncytial virus requires activation of NF-kappa B and is inhibited by sodium salicylate and aspirin Virology 232 1997 369
26. W. Tang, L. Yang, Y.C. Yang Transforming growth factor-beta stimulates interleukin-11 transcription via complex activating protein-1-dependent pathways J Biol Chem 273 1998 5506
27. M.T. Lin, R.C. Lee, P.C. Yang Cyclooxygenase-2 inducing Mcl-1-dependent survival mechanism in human lung adenocarcinoma CL1.0 cells. Involvement of phosphatidylinositol 3-kinase/Akt pathway J Biol Chem 276 2001 48997
28. X. Li, C.C. Pilbeam, L. Pan Effects of prostaglandin E2 on gene expression in primary osteoblastic cells from prostaglandin receptor knockout mice Bone 30 2002 567
29. D. Fujita, N. Yamashita, S. Iita Prostaglandin E2 induced the differentiation of osteoclasts in mouse osteoblast-depleted bone marrow cells Prostaglandins Leukot Essent Fatty Acids 68 2003 351