Modified method for determination of serum beta-glucuronidase: A comparative study using p-Nitrophenyl glucuronide and phenolphthalein glucuronide as substrate in gastrointestinal tract carcinomas

Indian Journal of Clinical Biochemistry

Volumn 12, Issue 1, 1997, Pages 67-70

  Khanolkar, M M ^a   Sirsat, A V ^a   Walvekar, S S ^a   Bhansali, M S ^a   Desouza, L J ^a  

^a TATA MEMORIAL HOSPITAL   (India)

Author keywords

Determination of glucuronidase; GIT carcinomas

Indexed keywords

EID: 33644880184     PISSN: 09701915     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02867959     Document Type: Article

References (9)

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2. Fishman, W.H. and Anlyan, A.J. (1947) Beta-glucuronidase activity in human tissues. Cancer Research 7, 808-818.
3. Rokicki, M., Rokicki, W., Paradysz, A. and Fryczkowski, M. (1992) Evaluation of the usefulness of analysis of beta-glucuronidase levels in patients with superficial cancer and papilloma of the bladder. Pol. Tyg. Lek 47(24-26), 528-529.
4. Taniguchi, T., Kiyohashi, A., Kitsuta, T. and Okabe, H. (1985) Changes in enzyme activities recognized in lymphocytes from patients with carcinomas of the gastrointestinal tract. Cell Mol. Biol. 31 (4), 259- 264.
5. Finch, P. J., Rogers, K. and Williams, B.T. (1986) Beta glucuronidase, LDH, and LDH isoenzyme levels and screening for gastric cancer. Eur. J. Surg. Oncol. 12(3), 253-256.
6. Ho-K-J (1995) Urinary beta-glucuronidase in screening and follow up of primary urinary tract malignancy. J. Urol. 154(4), 1335-1338.
7. Fishman, W.H., Springer, B. and Brunetti, R. (1948) Application of an improved glucuronidase assay -method to the study of human blood. J. Biol. Chem. 173, 449-456.
8. Szasz, G. (1967) Comparison between p-Nitrophenyl Glucuronide and Phenolphthaiein Glucuronide as substrates in the Assay of beta-glucuronidase. Clin. Chem. 13, 752-759.
9. Kato, K., Yoshida, K., Tsukamoto, H., Nobunaga, M., Masuya, T. and Sawada, T. (1960) Synthesis of p-nitro phenyl beta-D-glucopyranosiduronic acid and its utilisation as substrate for assay of beta-glucuronidase activity. Chem. Pharm. Bull. (Tokyo) 8, 239-242.