Development of resistance by Plasmodium falciparum to sulfadoxine/ pyrimethamine in Amhara Region, Northwestern Ethiopia

Ethiopian Medical Journal

Volumn 43, Issue 3, 2005, Pages 181-187

  Kassa, Moges ^a,c   Sileshi, Markos ^a   Mohammed, Hussien ^a   Taye, Girum ^a   Asfaw, Mekuanint ^b  

^a ETHIOPIAN PUBLIC HEALTH INSTITUTE   (Ethiopia)

^b Adiet Health Center

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

ANTIMALARIAL AGENT; PYRIMETHAMINE; SULFADOXINE;

ANIMAL; ARTICLE; CHILD; DRUG COMBINATION; DRUG EFFECT; DRUG RESISTANCE; ETHIOPIA; FEMALE; HUMAN; MALARIA FALCIPARUM; MALE; PLASMODIUM FALCIPARUM;

ANIMALS; ANTIMALARIALS; CHILD; DRUG RESISTANCE; DRUG THERAPY, COMBINATION; ETHIOPIA; FEMALE; HUMANS; MALARIA, FALCIPARUM; MALE; PLASMODIUM FALCIPARUM; PYRIMETHAMINE; SULFADOXINE;

EID: 33644878102     PISSN: 00141755     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. World Health Organization. Malaria. WHO, Geneva. Who Technical Report Series, No.8928, 2000.
2. Mutabingwa, T., Nzila, A.M, Mberu, E.K. et al. Chloroproguanil-dapson for treatment of drug-resistant falciparum malaria in Tanzania. Lancet, 2001;358 (9289): 1218-23.
3. White, NJ, Nosten, F., Looareesuwan, S. et al. Averting a malaria disaster. Lancet, 1999; 353: 1965-7.
4. Watkins, W.M and Mosobo, M.. Treatment of Plasmodium falciparum malaria with sulfadoxine/pyrimethamine: selective pressure for resistance is a function of lorig elimination half-life. Trans. Roy. Soc. Trop. Med. Hyg., 1993; 87:75-83.
5. Wornsdorfer, W. H. The development and spread of drug resistant malaria Parasitology Today, 1991; 7: 297-03.
6. Nzila, A.M, Mberu, E. K., Sulo, J. et al. Towards an understanding of the mechanism of pyrimethamine-sulfadoxine resistance in Plasmodium falciparum: genotyping of dihydrofolate reductase and dihydropteroate synthase of Kenyan parasites. Antimicrob Agents Chemother, 2000; 44, 991-6.
7. Teklehaimanot, A. Chloroquine resistant Plasmodium falciparum in Ethiopia, Lancet, 1986; 2: 127-9.
8. Wezam, A. Plasmodium falciparum sensitivity to antimalarials at Humera, North-western Ethiopia, Ethiop, Med. J., 1993; 31: 271-6.
9. Tulu, A. N., Webber, R. H., Schellenberg, J. A. and Bradley, D. J. Failure of chloroquine treatment for malaria in the highlands of Ethiopia, Trans. Roy. Soc. Trop. Med. Hyg., 1996; 90:556-67.
10. Abose, T., Yeebiyo, Y., Olana, D. et al. Re-Orientation and Definition of the Role of Malaria Vector - Control in Ethiopia. Geneva, World Health Organization, 1998 (document WHO/MAL/98.1085).
11. Gebreyesus, T and Alamirew, D. Response of Plasmodium falciparum to chloroquine and sulfadoxine/pyrimethamine in Areka and Sawla, Southern Ethiopia. Ethiop J Health Dev. 1998; 91-5.
12. MOH. Draft report on therapeutic efficacy of chloroquine, amodiaquine and sulfadoxine-pyrimethamine for treatment of uncomplicated falciparum malaria in Ethiopia. Malaria and Other Vector Borne Diseases Control Unit. Epidemeology and AIDS Department MOH.1998.
13. MOH. Malaria diagnosis and treatment guidelines for health workers in Ethiopia, Malaria and Other Vector Borne Diseases Control Unit. Epidemiology and Aids Department, 1999, Addis Ababa.
14. World Health Organization. The use of antimalarial drugs. Report of a WHO Technical Consultation. Geneva, World Health Organization, 2001 (document WHO/CDS/RBM/2001.33).
15. Kassa, M., Mengesha, T, Mekonnen, Y. et al. A randomized trial of sulfadoxine/pyrimethamine plus chloroquine versus sulfadoxine/pyrimethamine alone for the treatment of uncomplicated falciparum malaria in children, Metehara, Central Ethiopia. Eth. Pharm. J, 2001; 22:16-9.
16. World Health Organization. Malaria. Assessment of therapeutic efficacy of antimalarial drugs: for uncomplicated falciparum malaria in areas with intense transmission. Geneva, World Health Organization, 1996 (document WHO/MAL/96.1077).
17. Greenwood, B. M. and Armstrong, J. R. M. Comparison of two simple methods for determining malaria parasite density, Trans. Roy. Soc. Trop. Med. Hyg. 1991; 85:186-8.
18. D'Alessandro, U. and Buttiens, H. History and importance of antimalarial drugs, Tropical Medicine and International Health, 2001; 6:845-8.
19. Mengesha, T., Kassa, M., Tassew, G. et al. Malaria epidemics: Magnitude and precipitating factors. Proceedings of the workshop on vulnerability to epidemics: prevention and preparedness, 7 November 2002, Addis Ababa, Ethiopia.
20. Talisuna, A.O, Langi, P., Bakyaita, N. et al. Intensity of malaria transmission, antimalaria-drug use and resistance in Uganda: what is the relationship between these factors? Trans. Roy. Soc. Trop. Med. Hyg. 2002; 96:310-17.
21. MOH. Proceedings of the national workshop on anti-malarial treatment policy in Ethiopia, 25-26 May 2004, Addis Ababa, Ethiopia