Effect of donor-specific transfusions on the outcome of renal allografts in the cyclosporine era

Transplant International

Volumn 19, Issue 1, 2006, Pages 19-26

  Marti, Hans Peter ^a   Henschkowski, Jana ^a   Laux, Gunter ^b   Vogt, Bruno ^a   Seiler, Christian ^a   Opelz, Gerhard ^b   Frey, Felix J ^a  

^a UNIVERSITY OF BERN   (Switzerland)

^b UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Allograft rejection; Cyclosporine; Donor specific transfusion; Kidney transplantation; Living donation; Sensitization

Indexed keywords

AZATHIOPRINE; CYCLOSPORIN; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; PREDNISONE; IMMUNOSUPPRESSIVE AGENT;

ADULT; ARTICLE; BLOOD TRANSFUSION; CADAVER DONOR; CADAVER KIDNEY; COMPARATIVE STUDY; CONTROLLED STUDY; DONOR SELECTION; FEMALE; GRAFT SURVIVAL; HUMAN; KIDNEY ALLOGRAFT; KIDNEY GRAFT REJECTION; KIDNEY TRANSPLANTATION; LIVING DONOR; MAJOR CLINICAL STUDY; MALE; MONONUCLEAR CELL; PRIORITY JOURNAL; PROBABILITY; RECIPIENT; SENSITIZATION; TREATMENT OUTCOME; ALLOTRANSPLANTATION; DONOR; HISTOCOMPATIBILITY TEST; IMMUNOLOGY; MIDDLE AGED; MORTALITY; PHYSIOLOGY; SURVIVAL;

ADULT; BLOOD TRANSFUSION; CYCLOSPORINE; FEMALE; GRAFT SURVIVAL; HISTOCOMPATIBILITY TESTING; HUMANS; IMMUNOSUPPRESSIVE AGENTS; KIDNEY TRANSPLANTATION; MALE; MIDDLE AGED; SURVIVAL ANALYSIS; TISSUE DONORS; TRANSPLANTATION, HOMOLOGOUS;

EID: 33644877216     PISSN: 09340874     EISSN: 14322277     Source Type: Journal    
DOI: 10.1111/j.1432-2277.2005.00233.x     Document Type: Article

References (29)

1. Salvatierra O Jr. Melzer J Vincenti F et al. Donor-specific blood transfusions versus cyclosporine - the DST story. Transplant Proc 1987 19 1 Pt 1 160.
2. Salvatierra O Jr. Vincenti F Amend W et al. Deliberate donor-specific blood transfusions prior to living related renal transplantation. A new approach. Ann Surg 1980 192 543.
3. Amada N Okazaki H Sato T Miura S Ohashi Y. Prophylactic deoxyspergualin treatment in living-related renal-transplant recipients transfused with donor-specific blood. Transplantation 2003 75 60.
4. Otsuka M Yuzawa K Takada Y et al. Long-term results of donor-specific blood transfusion with cyclosporine in living related kidney transplantation. Nephron 2001 88 144.
5. Barber WH. Donor-specific transfusions in renal transplantation. Clin Transplant 1994 8 2 Pt 2 204.
6. Alexander JW Light JA Donaldson LA et al. Evaluation of pre- and post-transplant donor-specific transfusion/cyclosporine A in non-HLA identical living donor kidney transplant recipients. Cooperative Clinical Trials in Transplantation Research Group. Transplantation 1999 68 1117.
7. Otsuka M Yuzawa K Takada Y et al. Long-term graft survival of living-related kidneys after donor-specific transfusion. Transplant Proc 2000 32 1741.
8. Velidedeoglu E Tokyay R Haberal M. Effect of donor-specific blood transfusions on graft outcome in live donor renal transplantations. Transplant Proc 1992 24 2752.
9. Okazaki H Sato T Miura S Amada N. Donor-specific blood transfusion in living-related renal transplantation: fourteen-year experience. Transplant Proc 1997 29 200.
10. Anderson CB Brennan D Keller C et al. Beneficial effects of donor-specific transfusions on long-term renal allograft function. Transplant Proc 1995 27 991.
11. Sharma RK Rai PK Kumar A et al. Role of preoperative donor-specific transfusion and cyclosporine in haplo-identical living related renal transplant recipients. Nephron 1997 75 20.
12. Flye MW Burton K Mohanakumar T et al. Donor-specific transfusions have long-term beneficial effects for human renal allografts. Transplantation 1995 60 1395.
13. Salvatierra O McVicar J Melzer J et al. Improved results with combined donor-specific transfusion (DST) and sequential therapy protocol. Transplant Proc 1991 23 1 Pt 2 1024.
14. Kaplan EL Meier P. Nonparametric estimation from incomplete observations. J Am Stat Assoc 1958 53 457.
15. Meier-Kriesche HU Kaplan B. Waiting time on dialysis as the strongest modifiable risk factor for renal transplant outcomes: a paired donor kidney analysis. Transplantation 2002 74 1377.
16. Whelchel JD Shaw JF Curtis JJ Luke RG Diethelm AG. Effect of pretransplant stored donor-specific blood transfusions on early renal allograft survival in one-haplotype living related transplants. Transplantation 1982 34 326.
17. Light JA Metz S Oddenino K et al. Donor-specific transfusion with diminished sensitization. Transplantation 1982 34 352.
18. Norman DJ Henell K Fletcher L Barry J. Donor specific transfusions: a five-year experience with alternative protocols. Transplant Proc 1987 19 1 Pt 3 2252.
19. Anderson CB Sicard GA Etheredge EE. Pretreatment of renal allograft recipients with azathioprine and donor-specific blood products. Surgery 1982 92 315.
20. Cheigh JS Suthanthiran M Fotino M et al. Minimal sensitization and excellent renal allograft outcome following donor-specific blood transfusion with a short course of cyclosporine. Transplantation 1991 51 378.
21. Davies CB Alexander JW Cofer BR First MR Schroeder TJ. Efficacy of a single pretransplant donor-specific transfusion and cyclosporin A administered 24 to 48 hours before one-haplotype-mismatched living related donor kidney transplant. Ann Surg 1992 215 618.
22. Lezaic V Jovicic S Simic S et al. Donor-specific transfusion and renal allograft outcome. Nephron 2002 92 246.
23. Opelz G Vanrenterghem Y Kirste G et al. Prospective evaluation of pretransplant blood transfusions in cadaver kidney recipients. Transplantation 1997 63 964.
24. Wendel TD. The beneficial effect of donor-specific transfusions: a review of existing explanations and a new hypothesis based on a relatively unapplied theory of T cell immunoregulation. A regulatory hypothesis in progress. Med Hypotheses 2000 54 922.
25. Brennan DC Mohanakumar T Flye MW. Donor-specific transfusion and donor bone marrow infusion in renal transplantation tolerance: a review of efficacy and mechanisms. Am J Kidney Dis 1995 26 701.
26. Roelen D Brand A Claas FH. Pretransplant blood transfusions revisited: a role for CD(4+) regulatory T cells? Transplantation 2004 77 Suppl. 1 S26.
27. Womer KL Sayegh MH. Donor antigen and transplant tolerance strategies: it takes two to tango. J Am Soc Nephrol 2004 15 1101.
28. Kishimoto K Yuan X Auchincloss H Sharpe AH Mandelbrot DA Sayegh MH. Mechanism of action of donor-specific transfusion in inducing tolerance: role of donor MHC molecules, donor co-stimulatory molecules, and indirect antigen presentation. J Am Soc Nephrol 2004 15 2423.
29. Sandner SE Clarkson MR Salama AD et al. Mechanism of tolerance induced by donor-specific transfusion and ICOS-B7h blockade in a model of CD4+ T-cell-mediated allograft rejection. Am J Transplant 2005 5 31.