Molecular characterization of a balanced chromosome translocation in psoriasis vulgaris [4]

Clinical Genetics

Volumn 69, Issue 2, 2006, Pages 189-193

  Tzschach, Andreas ^a   Hoffmann, K ^b   Hoeltzenbein, M ^b   Bache, I ^b   Tommerup, N ^b   Bommer, C ^b   Korner H ^b   Kalscheuer, V ^b   Ropers, H H ^b  

^a MAX PLANCK INSTITUTE FOR MOLECULAR GENETICS   (Germany)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

GENOMIC DNA; GLUTATHIONE TRANSFERASE; LEUKOTRIENE A4; LEUKOTRIENE B4; LEUKOTRIENE C4; MESSENGER RNA;

ADULT; CASE REPORT; CHROMOSOME TRANSLOCATION 2; CHROMOSOME TRANSLOCATION 4; EXON; FAMILIAL DISEASE; FIBROBLAST; FLUORESCENCE IN SITU HYBRIDIZATION; GENE MUTATION; GENETIC SCREENING; HETEROZYGOTE; HUMAN; KARYOTYPE 46,XY; LETTER; LYMPHOBLASTOID CELL; MALE; MOLECULAR CLONING; MOLECULAR GENETICS; NORTHERN BLOTTING; PRIORITY JOURNAL; PROTEIN METABOLISM; PSORIASIS VULGARIS; RESTRICTION MAPPING; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SOUTHERN BLOTTING;

ADULT; BASE SEQUENCE; CHROMOSOMES, HUMAN, PAIR 2; CHROMOSOMES, HUMAN, PAIR 4; EXONS; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; INTRONS; LEUKOTRIENES; MALE; PSORIASIS; TRANSLOCATION, GENETIC;

EID: 33644871113     PISSN: 00099163     EISSN: 13990004     Source Type: Journal    
DOI: 10.1111/j.1399-0004.2005.00558.x     Document Type: Letter

References (27)

1. Nevitt GJ, Hutchinson PE. Psoriasis in the community: Prevalence, severity and patients' beliefs and attitudes towards the disease. Br J Dermatol 1996: 135 (4): 533-537.
2. Schon MP, Boehncke WH. Psoriasis. N Engl J Med 2005: 352 (18): 1899-1912.
3. Lomholt G. Prevalence of skin diseases in a population; a census study from the Faroe Islands. Dan Med Bull 1964: 11: 1-7.
4. Brandrup F, Holm N, Grunnet N et al. Psoriasis in monozygotic twins: variations in expression in individuals with identical genetic constitution. Acta Derm Venereol 1982: 62 (3): 229-236.
5. Sagoo GS, Tazi-Ahnini R, Barker JW et al. Meta-analysis of genome-wide studies of psoriasis susceptibility reveals linkage to chromosomes 6p21 and 4q28-q31 in Caucasian and Chinese Hans population. J Invest Dermatol 2004: 122 (6): 1401-1405.
6. Nair RP, Henseler T, Jenisch S et al. Evidence for two psoriasis susceptibility loci (HLA and 17q) and two novel candidate regions (16q and 20p) by genome-wide scan. Hum Mol Genet 1997: 6 (8): 1349-1356.
7. Trembath RC, Clough RL, Rosbotham JL et al. Identification of a major susceptibility locus on chromosome 6p and evidence for further disease loci revealed by a two stage genome-wide search in psoriasis. Hum Mol Genet 1997: 6 (5): 813-820.
8. Samuelsson L, Enlund F, Torinsson A et al. A genome-wide search for genes predisposing to familial psoriasis by using a stratification approach. Hum Genet 1999: 105 (6): 523-529.
9. Veal CD, Clough RL, Barber RC et al. Identification of a novel psoriasis susceptibility locus at 1p and evidence of epistasis between PSORS1 and candidate loci. J Med Genet 2001: 38 (1): 7-13.
10. Zhang XJ, He PP, Wang ZX et al. Evidence for a major psoriasis susceptibility locus at 6p21 (PSORS1) and a novel candidate region at 4q31 by genome-wide scan in Chinese hans. J Invest Dermatol 2002: 119 (6): 1361-1366.
11. Karason A, Gudjonsson JE, Jonsson HH et al. Genetics of psoriasis in Iceland: Evidence for linkage of subphenotypes to distinct loci. J Invest Dermatol 2005: 124 (6): 1177-1185.
12. Bugge M, Bruun-Petersen G, Brondum-Nielsen K et al. Disease associated balanced chromosome rearrangements: A resource for large scale genotype-phenotype delineation in man. J Med Genet 2000: 37 (11): 858-865.
13. Blackwood DH, Fordyce A, Walker MT et al. Schizophrenia and affective disorders - cosegregation with a translocation at chromosome 1q42 that directly disrupts brain-expressed genes: Clinical and P300 findings in a family. Am J Hum Genet 2001: 69 (2): 428-433.
14. Taipale M, Kaminen N, Nopola-Hemmi J et al. A candidate gene for developmental dyslexia encodes a nuclear tetratricopeptide repeat domain protein dynamically regulated in brain. Proc Natl Acad Sci USA 2003: 100 (20): 11553-11558.
15. Wirth J, Nothwang HG, van der Maarel S et al. Systematic characterisation of disease associated balanced chromosome rearrangements by FISH: Cytogenetically and genetically anchored YACs identify microdeletions and candidate regions for mental retardation genes. J Med Genet 1999: 36 (4): 271-278.
16. Siebert PD, Chenchik A, Kellogg DE et al. An improved PCR method for walking in uncloned genomic DNA. Nucl Acids Res 1995: 23 (6): 1087-1088.
17. Vanhee-Brossollet C, Vaquero C. Do natural antisense transcripts make sense in eukaryotes? Gene 1998: 211 (1): 1-9.
18. Munroe SH, Lazar MA. Inhibition of c-erbA mRNA splicing by a naturally occurring antisense RNA. J Biol Chem 1991: 266 (33): 22083-22086.
19. Okano H, Aruga J, Nakagawa T et al. Myelin basic protein gene and the function of antisense RNA in its repression in myelin-deficient mutant mouse. J Neurochem 1991: 56 (2): 560-567.
20. Hildebrandt M, Nellen W. Differential antisense transcription from the Dictyostelium EB4 gene locus. implications on antisense-mediated regulation of mRNA stability. Cell 1992: 69 (1): 197-204.
21. Savage MP, Fallon JF. FGF-2 mRNA and its antisense message are expressed in a developmentally specific manner in the chick limb bud and mesonephros. Dev Dyn 1995: 202 (4): 343-353.
22. Kimelman D, Kirschner MW. An antisense mRNA directs the covalent modification of the transcript encoding fibroblast growth factor in Xenopus oocytes. Cell 1989: 59 (4): 687-696.
23. Wightman B, Ha I, Ruvkun G. Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans. Cell 1993: 75 (5): 855-862.
24. Sjostrom M, Jakobsson PJ, Heimburger M et al. Human umbilical vein endothelial cells generate leukotriene C4 via microsomal glutathione S-transferase type 2 and express the CysLT(1) receptor. Eur J Biochem 2001: 268 (9): 2578-2586.
25. Brain S, Camp R, Dowd P et al. The release of leukotriene B4-like material in biologically active amounts from the lesional skin of patients with psoriasis. J Invest Dermatol 1984: 83 (1): 70-73.
26. Dlugaszewska B, Silahtaroglu A, Menzel C et al. Breakpoints around the HOXD cluster result in various limb malformations. J Med Genet 2005: June 24 Epub ahead of print.
27. Velagaleti GV, Bien-Willner GA, Northup JK et al. Position effects due to chromosome breakpoints that map approximately 900 Kb upstream and approximately 1.3 Mb downstream of SOX9 in two patients with campomelic dysplasia. Am J Hum Genet 2005: 76 (4): 652-662.