Downloadable computer models for renal replacement therapy

Kidney International

Volumn 69, Issue 6, 2006, Pages 1056-1063

  Walther, J L ^a,b   Bartlett, D W ^a,b   Chew, W ^a   Robertson, C R ^b   Hostetter, T H ^c   Meyer, T W ^a,d  

^a STANFORD UNIVERSITY   (United States)

^b Stanford University   (United States)

^c ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^d NONE   (United States)

Author keywords

Computer; Hemodialysis; Hemofiltration; Modeling

Indexed keywords

ARTICLE; ARTIFICIAL KIDNEY; BLOOD FLOW; BLOOD LEVEL; COMPUTER MODEL; COMPUTER PROGRAM; CONCENTRATION (PARAMETERS); DIALYSATE; DIFFUSION; FLOW RATE; HEMODIALYSIS; HEMOFILTRATION; INTERNET; MATHEMATICAL MODEL; PLASMA CLEARANCE; PRIORITY JOURNAL; PROTEIN BINDING; RENAL REPLACEMENT THERAPY; SOLUTE; THERMODYNAMICS; TREATMENT DURATION;

ANIMALS; COMPUTER SIMULATION; GLOMERULAR FILTRATION RATE; HEMATOCRIT; HEMODIALYSIS SOLUTIONS; HUMANS; MEMBRANES, ARTIFICIAL; METABOLIC CLEARANCE RATE; MODELS, THEORETICAL; RENAL CIRCULATION; RENAL DIALYSIS; RENAL REPLACEMENT THERAPY; SOFTWARE; TIME FACTORS;

EID: 33644866909     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1038/sj.ki.5000196     Document Type: Article

References (16)

1. Depner TA. Prescribing Hemodialysis: A Guide to Urea Modeling. Kluwer Academic Publishers: Boston, MA, 1991: 320pp.
2. Michaels AS. Operating parameters and performance criteria for hemodialyzers and other membrane-separation devices. Trans Am Soc Artif Intern Organs 1966; 2: 387-392.
3. Villarroel F, Klein E, Holland F. Solute flux in hemodialysis and hemofiltration membranes. Trans Am Soc Artif Intern Organs 1977; 23: 225-233.
4. Jaffrin MY, Ding LH, Laurent JM. Simultaneous convective and diffusive mass transfers in a hemodialyser. J Biomech Eng 1990; 112: 212-219.
5. Jaffrin MY. Convective mass transfer in hemodialysis. Artif Organs 1995; 19: 1162-1171.
6. Waniewski J, Werynski A, Ahrenholz P et al. Theoretical basis and experimental verification of the impact of ultrafiltration on dialyzer clearance. Artif Organs 1991; 15: 70-77.
7. Meyer TW, Leeper EC, Bartlett DW et al. Increasing dialysate flow and dialyzer mass transfer area coefficient to increase the clearance of protein-bound solutes. J Am Soc Nephrol 2004; 15: 1927-1935.
8. Meyer TW, Walther JL, Pagtalunan ME et al. The clearance of protein-bound solutes by hemofiltration and hemodiafiltration. Kidney Int 2005; 68: 867-877.
9. Gotch FA, Panlilio F, Sergeyeva O et al. Effective diffusion volume flow rates (Qe) for urea, creatinine, and inorganic phosphorous (Qeu, Qecr, QeiP) during hemodialysis. Semin Dial 2003; 16: 474-476.
10. Clark WR, Leypoldt JK, Henderson LW et al. Quantifying the effect of changes in the hemodialysis prescription on effective solute removal with a mathematical model. J Am Soc Nephrol 1999; 10: 601-609.
11. Nolph KD, Keshaviah P, Emerson P et al. A new approach to optimizing urea clearances in hemodialysis and continuous ambulatory peritoneal dialysis. Asaio J 1995; 41: M446-M451.
12. Daugirdas JT, Greene T, Depner TA et al. Anthropometrically estimated total body water volumes are larger than modeled urea volume in chronic hemodialysis patients: effects of age, race, and gender. Kidney Int 2003; 64: 1108-1119.
13. Vanholder R, De Smet R, Glorieux G et al. Review on uremic toxins: classification, concentration, and interindividual variability. Kidney Int 2003; 63: 1934-1943.
14. Depner TA, Greene T, Daugirdas JT et al. Dialyzer performance in the MEMO Study: in vivo K0A and true blood flow determined from a model of cross-dialyzer urea extraction. Asaio J 2004; 50: 85-93.
15. Harvey AM. Classics in clinical science: the concept of renal clearance. Am J Med 1980; 68: 6-8.
16. Lucchi L, Fiore GB, Guadagni G et al. Clinical evaluation of internal hemodiafiltration (iHDF): a diffusive-convective technique performed with internal filtration enhanced high-flux dialyzers. Int J Artif Organs 2004; 27: 414-419.