β-myosin heavy chain myocytes are more resistant to changes in power output induced by ischemic conditions

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 290, Issue 2, 2006, Pages

  Hinken, Aaron C ^a   McDonald, Kerry S ^a,b  

^a University of Missouri   (United States)

^b MA415 MSB ^*  (United States)

Author keywords

Inorganic phosphate; Ischemia; Loaded shortening velocity; Power output

Indexed keywords

5 N PROPYL 2 THIOURACIL; MYOSIN HEAVY CHAIN ALPHA; MYOSIN HEAVY CHAIN BETA; THIOURACIL DERIVATIVE; UNCLASSIFIED DRUG; ANTIMETABOLITE; BMYO PROTEIN, RAT; MYOSIN HEAVY CHAIN; PHOSPHATE; PROPYLTHIOURACIL; VENTRICULAR MYOSIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; FORCE TRANSDUCER; HEART MUSCLE CELL; HEART MUSCLE ISCHEMIA; HEART OUTPUT; HEART WORK; MAJOR HISTOCOMPATIBILITY COMPLEX; MALE; MUSCLE FIBRIL; MUSCLE ISOMETRIC CONTRACTION; NONHUMAN; PH; PRIORITY JOURNAL; RAT; ANIMAL; DRUG ANTAGONISM; DRUG EFFECT; ENERGY METABOLISM; METABOLISM; MUSCLE CONTRACTION; PATHOPHYSIOLOGY; SPRAGUE DAWLEY RAT;

ANIMALS; ANTIMETABOLITES; ENERGY METABOLISM; HYDROGEN-ION CONCENTRATION; MALE; MUSCLE CONTRACTION; MYOCARDIAL ISCHEMIA; MYOCYTES, CARDIAC; MYOSIN HEAVY CHAINS; PHOSPHATES; PROPYLTHIOURACIL; RATS; RATS, SPRAGUE-DAWLEY; VENTRICULAR MYOSINS;

EID: 33644865218     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00221.2005     Document Type: Article

References (42)

1. Araujo A and Walker JW. Phosphate release and force generation in cardiac myocytes investigated with caged phosphate and caged calcium. Biophys J 70: 2316-2326, 1996.
2. Asano G, Takashi E, Ishiwata T, Onda M, Yokoyama M, Naito Z, Ashraf M, and Sugisaki Y. Pathogenesis and protection of ischemia and reperfusion injury in myocardium. J Nippon Med Sch 70: 384-392, 2003.
3. Blunt BC, Chen Y, Potter JD, and Hofmann PA. Modest actomyosin energy conservation increases myocardial postischemic function. Am J Physiol Heart Circ Physiol 288: H1088-H1096, 2005.
4. Bolli R and Marban E. Molecular and cellular mechanisms of myocardial stunning. Physiol Rev 79: 609-634, 1999.
5. Cave AC, Ingwall JS, Friedrich J, Liao R, Saupe KW, Apstein CS, and Eberli FR. ATP synthesis during low-flow ischemia: influence of increased glycolytic substrate. Circulation 101: 2090-2096, 2000.
6. Debold EP, Dave H, and Fitts RH. Fiber type and temperature dependence of inorganic phosphate: implications for fatigue. Am J Physiol Cell Physiol 287: C673-C681, 2004.
7. Ebus JP, Stienen GJ, and Elzinga G. Influence of phosphate and pH on myofibrillar ATPase activity and force in skinned cardiac trabeculae from rat. J Physiol (Lond) 476: 501-516, 1994.
8. Elliott AC, Smith GL, Eisner DA, and Allen DG. Metabolic changes during ischaemia and their role in contractile failure in isolated ferret hearts. J Physiol (Lond) 454: 467-490, 1992.
9. Fabiato A. Computer programs for calculating total from specified free or free from specified total ionic concentrations in aqueous solutions containing multiple metals and ligands. Methods Enzymol 157: 378-417, 1988.
10. Fabiato A and Fabiato F. Effects of pH on the myofilaments and the sarcoplasmic reticulum of skinned cells from cardiac and skeletal muscles. J Physiol (Lond) 276: 233-255, 1978.
11. Fitzsimons DP, Patel JR, and Moss RL. Role of myosin heavy chain composition in kinetics of force development and relaxation in rat myocardium. J Physiol (Lond) 513: 171-183, 1998.
12. Herron TJ, Korte FS, and McDonald KS. Loaded shortening and power output in cardiac myocytes are dependent on myosin heavy chain isoform expression. Am J Physiol Heart Circ Physiol 281: H1217-H1222, 2001.
13. Hibberd MG, Dantzig JA, Trentham DR, and Goldman YE. Phosphate release and force generation in skeletal muscle fibers. Science 228: 1317-1319, 1985.
14. Hill AV. The heat of shortening and the dynamic constants of muscle. Proc R Soc Lond Ser B 126: 136-195, 1938.
15. Hinken AC and McDonald KS. Inorganic phosphate speeds loaded shortening in rat skinned cardiac myocytes. Am J Physiol Cell Physiol 287: C500-C507, 2004.
16. Hoh JF and Egerton LJ. Action of triidothyronine on the synthesis of rat ventricular myosin isoenzymes. FEBS Lett 101: 143-148, 1979.
17. Kentish JC. Combined inhibitory actions of acidosis and phosphate on maximum force production in rat skinned cardiac muscle. Pflügers Arch 419: 310-318, 1991.
18. Kentish JC. The effects of inorganic phosphate and creatine phosphate on force production in skinned muscles from rat ventricle. J Physiol 370: 585-604, 1986.
19. Kushmerick M. Energetics studies of muscles of different types. Basic Res Cardiol 82: 17-30, 1987.
20. 2+-activated force by inorganic phosphate. Circ Res 59: 270-282, 1986.
21. Litten RZ, Martin BJ, Low RB, and Alpert NR. Altered myosin isozyme patterns from pressure-overloaded and thyrotoxic hypertrophied rabbit hearts. Circ Res 50, 1982.
22. 2+ dependence of loaded shortening in rat skinned cardiac myocytes and skeletal muscle fibers. J Physiol (Lond) 525: 169-181, 2000.
23. McNally EM, Kraft R, Bravo-Zehnder M, Taylor DA, and Leinwand LA. Full-length rat alpha and beta cardiac myosin heavy chain sequences. J Mol Biol 210: 665-671, 1989.
24. Metzger JM. pH dependence of myosin binding-induced activation of the thin filament in cardiac myocytes and skeletal fibers. Am J Physiol Heart Circ Physiol 270: H1008-H1014, 1996.
25. Metzger JM and Moss RL. Effects on tension and stiffness due to reduced pH in mammalian fast- and slow-twitch skinned skeletal muscle fibres. J Physiol (Lond) 428: 737-750, 1990.
26. Metzger JM and Moss RL. Phosphate and the kinetics of force generation in skinned skeletal muscle fibers (Abstract). Biophys J 59: 418A, 1991.
27. Millar NC and Homsher E. The effect of phosphate and calcium on force generation in glycerinated rabbit skeletal muscle fibers. J Biol Chem 265: 20234-20240, 1990.
28. Moss RL. Sarcomere length-tension relations of frog skinned muscle fibres during calcium activation at short lengths. J Physiol (Lond) 292: 177-202, 1979.
29. Nosek TM, Leal-Cardoso JH, McLaughlin M, and Godt RE. Inhibitory influence of phosphate and arsenate on contraction of skinned skeletal and cardiac muscle. Am J Physiol Cell Physiol 259: C933-C939, 1990.
30. Orchard CH and Kentish JC. Effects of changes of pH on the contractile function of cardiac muscle. Am J Physiol Cell Physiol 258: C967-C981, 1990.
31. Potma EJ, van Graas IA, and Stienen GJ. Influence of inorganic phosphate and pH on ATP utilization in fast and slow skeletal muscle fibers. Biophys J 69: 2580-2589, 1995.
32. Reiser PJ, Portman MA, Ning XH, and Moravec CS. Human cardiac myosin heavy chain isoforms in fetal and failing adult atria and ventricles. Am J Physiol Heart Circ Physiol 280: H1814-H1820, 2001.
33. Ricciardi L, Bottinelli R, Canepari M, and Reggiani C. Effects of acidosis on maximum shortening velocity and force-velocity relation of skinned rat cardiac muscle. J Mol Cell Cardiol 26: 601-607, 1994.
34. Rundell VL, Manaves V, Martin AF, and de Tombe PP. Impact of β-myosin heavy chain isoform expression on cross-bridge cycling kinetics. Am J Physiol Heart Circ Physiol 288: H896-H903, 2005.
35. Smith GL, Donoso P, Bauer CJ, and Eisner DA. Relationship between intracellular pH and metabolite concentrations during metabolic inhibition in isolated ferret heart. J Physiol (Lond) 472: 11-22, 1993.
36. Solaro RJ, Kumar P, Blanchard EM, and Martin AF. Differential effects of pH on calcium activation of myofilaments of adult and perinatal dog hearts. Circ Res 58: 721-729, 1986.
37. Stienen GJM, Roosemalen MCM, Wilson MGA, and Elzinga G. Depression of force by phosphate in skinned muscle fibers of the frog. Am J Physiol Cell Physiol 259: C349-C357, 1990.
38. Tesi C, Colomo F, Piroddi N, and Poggesi C. Characterization of the cross-bridge force-generating step using inorganic phosphate and BDM in myofibrils from rabbit skeletal muscles. J Physiol (Lond) 54: 187-199, 2002.
39. Van der Velden J, Klein LJ, Zaremba R, Boontje NM, Huybregts MAJM, Stooker W, Eijsman L, de Jong JW, Visser CA, Visser FC, and Stienen GJM. Effects of calcium, inorganic phosphate, and pH on isometric force in single skinned cardiomyocytes from donor and failing human hearts. Circulation 104: 1140-1146, 2001.
40. Woledge RC, Curtin NA, and Homsher E. Energetic Aspects of Muscle Contraction. London: Academic, p. 47-71, 1985.
41. Xu YJ, Chapman D, Dixon IM, Sethi R, Guo X, and Dhalla NS. Differential gene expression in infarct scar and viable myocardium from rat heart following coronary ligation. J Cell and Mol Med 8: 85-92, 2004.
42. Yue P, Long C, Austin R, Chang K, Simpson P, and Massie B. Post-infarction heart failure in the rat is associated with distinct alterations in cardiac muscle molecular phenotype. J Mol Cell Cardiol 30: 1615-1630, 1998.