Ontogeny of VEGF, IGF-I, and GH in neonatal rat serum, vitreous fluid, and retina from birth to weaning

Investigative Ophthalmology and Visual Science

Volumn 47, Issue 2, 2006, Pages 738-744

  Modanlou, Houchang D ^a   Gharraee, Zahra ^a,b   Hasan, Jamal ^a,b   Waltzman, Joshua ^c   Nageotte, Stephen ^c   Beharry, Kay D A ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b MILLER CHILDREN S HOSPITAL   (United States)

^c Memorial Health Services   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GROWTH HORMONE; SOMATOMEDIN C; VASCULOTROPIN; VASCULAR ENDOTHELIAL GROWTH FACTOR A, RAT; VASCULOTROPIN A;

ANIMAL TISSUE; ARTICLE; BIRTH; BLOOD ANALYSIS; CONTROLLED STUDY; FEMALE; HORMONE BLOOD LEVEL; HORMONE DETERMINATION; NONHUMAN; ONTOGENY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BLOOD LEVEL; RAT; RETINA; RETINA DEVELOPMENT; VITREOUS BODY; WEANING; ANIMAL; BLOOD; GROWTH, DEVELOPMENT AND AGING; METABOLISM; NEWBORN; PREGNANCY; SPRAGUE DAWLEY RAT; VISUAL SYSTEM FUNCTION;

ANIMALS; ANIMALS, NEWBORN; FEMALE; GROWTH HORMONE; INSULIN-LIKE GROWTH FACTOR I; OCULAR PHYSIOLOGY; PREGNANCY; RATS; RATS, SPRAGUE-DAWLEY; RETINA; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VITREOUS BODY;

EID: 33644863972     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: 10.1167/iovs.05-1046     Document Type: Article

References (48)

1. Hameed B, Shyamanur K, Kotecha S, Manktelow BN, Woodruff G, Draper ES. Trends in the incidence of severe retinopathy of prematurity in a geographically defined population over a 10-year period. Pediatrics. 2004;113:1653-1657.
2. Phelps DL. Retinopathy of prematurity. Pediatr Clin North Am. 2004;40:705-714.
3. O'Conner MT, Vohr BR, Tucker R, Cashore W. Is retinopathy of prematurity increasing among infants less than 1250 g birth weight? J Perinatol. 2003;23:673-678.
4. Simons BD, Flynn JT. Retinopathy of prematurity and associated factors. Int Ophthalmol Clin. 1999;39:29-48.
5. Chow LC, Wright KW, Sola A. The Cedars Sinai Medical Center Oxygen Administration Study Group. Can changes in clinical practice decrease the incidence of severe retinopathy of prematurity in very low birth weight infants? Pediatrics. 2003;111:339-345.
6. Smith LEH. Pathogenesis of retinopathy of prematurity. Semin Neonatol. 2003;8:469-473.
7. Hikino S, Ihara K, Yamamoto J, et al. Physical growth and retinopathy in preterm infants: involvement of IGF-I and GH. Pediatr Res. 2001;50:732-736.
8. Hellstrom A, Engstrom E, Hard A-L, et al. Postnatal serum insulin-like growth factor I deficiency is associated with retinopathy of prematurity and other complications of premature birth. Pediatrics. 2003;112:1016-1020.
9. Hellstrom A, Perruzzi C, Ju M, et al. Low IGF-I suppresses VEGF-survival signaling in retinal endothelial cells: direct correlation with clinical retinopathy of prematurity. Proc Natl Acad Sci USA. 2001;98:5804-5808.
10. Arnold DR, Moshayedi P, Schoen TJ, Jones BE, Chader GJ, Waldbillig RJ. Distribution of IGF-I, IGF binding proteins (IGFBPs) and IGFBP mRNA in ocular fluids and tissues: potential sites of synthesis of IGFBPs in aqueous and vitreous. Exp Eye Res. 1993;56:555-565.
11. Ricci B. Effects of hyperbaric, normobaric and hypobaric supplementation on retinal vessels in newborn rats: a preliminary study. Exp Eye Res. 1987;44:459-464.
12. Roth AM. Retinal vascular development in premature infants. Am J Ophthalmol. 1997;84:636-640.
13. Foos R, Kopelow S. Development of retinal vasculature in prenatal infants. Surv Ophthalmol. 1973;18:117-127.
14. Michaelson, I. The mode of development of the vascular system of the retina with some observations in its significance for certain retinal diseases. Trans Ophthalmol Soc UK. 1948;68:137-180.
15. Ashton N, Ward B, Serpell G. Effect of oxygen on developing retinal vessels with particular reference to the problem of retrolental fibroplasia. Br J Ophthalmol. 1954;38:397-432.
16. Penn JS, Tolman BL, Lowery LA, Koutz CA. Oxygen-induced retinopathy in the rat: hemorrhages and dysplasias may lead to retinal detachment. Curr Eye Res. 1992;11:939-953.
17. Penn JS, Tolman BL, Lowery LA. Variable oxygen exposure causes preretinal neovascularization in the newborn rat. Invest Ophthalmol Vis Sci. 1993;34:576-585.
18. Penn JS, Henry MM, Tolman BL. Exposure to alternating hypoxia and hyperoxia causes severe proliferative retinopathy in the newborn rat. Pediatr Res. 1994;36:724-731.
19. Penn JS, Tolman BL, Henry MM. Oxygen-induced retinopathy in the rat: relationship of retinal nonperfusion to subsequent neovascularization. Invest Ophthalmol Vis Sci. 1994;35:3429-3435.
20. Penn JS, Henry MM, Wall PT, Tolman BL. The range of PaO2 variation determines the severity of oxygen-induced retinopathy in newborn rats. Invest Ophthalmol Vis Sci. 1995;6:2063-2070.
21. Hellstrom A, Svensson E, Carlsson B, Niklasson A, Albertsson-Wikland K. Reduced retinal vascularization in children with growth hormone deficiency. Clin Endocrinol Metab. 1999;4:795-798.
22. Smith LEH, Kopchick JJ, Chen W, et al. Essential role of growth hormone in ischemia-induced retinal neovascularization. Science. 1997;276:1706-1709.
23. Hellstrom A, Carlsson B, Niklasson A, et al. IGF-I is critical for normal vascularization of the human retina. J Clin Endocrinol Metab. 2002;87:3413-3416.
24. Moriarty P, Boulton M, Dickson A, Mcleod D. Production of IGF-I and IGF binding proteins by retinal cells in vitro. Br J Ophthalmol. 1994;78:638-642.
25. Takagi H, Yoshimma N, Tanihara H, Honda Y. Insulin-like growth factor-related genes, receptors and binding proteins in cultured human retinal pigment epithelial cells. Invest Ophthalmol Vis Sci. 1994;35:916-923.
26. Ocrant I, Fay CT, Parmelee TT. Expression of insulin and insulin-like growth factor receptors and binding proteins by retinal pigment epithelium. Exp Eye Res. 1991;52:581-589.
27. Tanihara H, Inatani M, Honda Y. Growth factors and their receptors in the retina and pigment epithelium. Prog Retin Eye Res. 1997;16:271-301.
28. Bauer MK, Harding JE, Bassett NS, et al. Fetal growth and placental function. Mol Cell Endocrinol. 1998;140:115-120.
29. Lineham JD, Smith RM, Dahlenburg GW, et al. Circulating insulin-like growth factor-I levels in newborn premature and full-term infants followed longitudinally. Early Hum Dev. 1986;13:37-46.
30. Gluckman PD, Harding JE. The physiology and the pathophysiology of intrauterine growth retardation. Hormone Res. 1997;48(suppl 1):11-16.
31. Giudice LC, De Zagher F, Gargosky SE, et al. Insulin-like growth factors and their binding proteins in the term and preterm human fetus and neonate with normal and extremes of intrauterine growth. J Clin Endocr Metab. 1995;80:1548-1555.
32. Radetti G, Bozzola M, Paganini C, et al. Growth hormone bioactivity and levels of growth hormone, growth hormone-binding protein, insulinlike growth factor I, and insulinlike growth factor-binding proteins in premature and full-term newborns during the first month of life. Arch Pediatr Adolesc Med. 1997;151:170-175.
33. Rajaram S, Carlson SE, Koo WW, Rangachari A, Kelly DP. Insulin-like growth factor (IGF)-I and IGF-binding protein 3 during the first year in term and preterm infants. Pediatr Res. 1995;37:581-585.
34. Pierce EA, Avery RL, Foley ED, Aiello LP, Smith LE. Vascular endothelial growth factor/vascular permeability factor expression in a mouse model of retinal neovascularization. Proc Natl Acad Sci USA. 1995;92:905-909.
35. Pierce EA, Foley ED, Smith LEH. Regulation of vascular endothelial growth factor by oxygen in a model of retinopathy of prematurity (published correction appears in Arch Ophthalmol. 1997;115: 427). Arch Ophthalmol. 1996;114:1219-1228.
36. Stone J, Itin A, Alon T, et al. Development of retinal vasculature is mediated by hypoxia-induced vascular endothelial growth factor (VEGF) expression in neuroglia. J Neurosci. 1995;15:4738-4747.
37. Alon T, Hemo I, Itin A, Pe'er J, Keshet E. Vascular endothelial growth factor (VEGF) acts as a survival factor for the newly formed vessels and has implications for retinopathy of prematurity. Nat Med. 1995;1:1024-1028.
38. Ozaki H, Seo MS, Ozaki K, et al. Blockade of vascular endothelial cell growth factor receptor signaling is sufficient to completely prevent retinal neovascularization. Am J Pathol. 2000;156:697-707.
39. Aiello LP, Avery RL, Arrigg PG, et al. Vascular endothelial growth factor in ocular fluid of patients with diabetic retinopathy and other retinal disorders. N Engl J Med. 1994;331:1480-1487.
40. Aiello LP, Pierce EA, Foley ED, et al. Suppression of retinal neovascularization in vivo by inhibition of vascular endothelial growth factor (VEGF) using soluble VEGF-receptor chimeric proteins. Proc Natl Acad Sci USA. 1995;92:10457-10461.
41. Robinson GS, Pierce EA, Rook SL, Foley E, Webb R, Smith LE. Oligodeoxynucleotides inhibit retinal neovascularization in a murine model of proliferative retinopathy. Proc Natl Acad Sci USA. 1996;3:4851-4856.
42. Cunningham S, McColm JR, Wade J, Sedowofia K, Mcintosh N, Fleck B. A novel model of retinopathy of prematurity simulating preterm oxygen variability in the rat. Invest Ophthalmol Vis Sci. 2000;1:4275-4280.
43. Ashton N. Oxygen and the growth and development of retinal vessels. In vivo and in vitro studies. The XX Francis I. Proctor Lecture. Am J Ophthalmol. 1996;2:412-435.
44. Smith LEH, Wesolowski E, McLellan A, et al. Oxygen-induced retinopathy in the mouse. Invest Ophthalmol Vis Sci. 1994;5:101-111.
45. Mcleod D, Crone S, Lutty G. Vasoproliferation in the neonatal dog model of oxygen-induced retinopathy. Invest Ophthalmol Vis Sci. 1996;37:1322-1333.
46. Castellon R, Hamdi HK, Sacerio I, Aoki AM, Kenney MC, Ljubimov AV. Effects of angiogenic growth factor combinations on retinal endothelial cells. Exp Eye Res. 2002;74:523-535.
47. Smith LEH, Shen W, Perruzzi C, et al. Regulation of vascular growth factor-dependent retinal neovascularization by insulin-like growth factor-I receptor. Nat Med. 1999;5:1390-1395.
48. Burgos R, Simo R, Audi L, et al. Vitreous levels of vascular endothelial growth factor are not influenced by its serum concentrations in diabetic retinopathy. Diabetologia. 1997;40:1107-1109.