Feeding a corn oil/sucrose-enriched diet enhances steatohepatitis in sedentary rats

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 290, Issue 2, 2006, Pages

  Rivera, C A ^a,b   Abrams, S H ^b   Tcharmtchi, M H ^b   Allman, M ^a   Ziba, T T ^b   Finegold, M J ^b   Smith, C W ^b  

^a LOUISIANA STATE UNIVERSITY HEALTH SCIENCES CENTER   (United States)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

Endotoxin; Hindlimb unloading; Liver; Steatohepatitis

Indexed keywords

CORN OIL; CYTOKINE; ENDOTOXIN; INSULIN; SUCROSE; AMINOTRANSFERASE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD ANALYSIS; BLOOD SAMPLING; CALORIC INTAKE; CHEMICAL ANALYSIS; CLINICAL FEATURE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DIET SUPPLEMENTATION; ENDOTOXEMIA; FATTY LIVER; FEEDING; GLUCOSE INTAKE; HEPATITIS; HYPERINSULINEMIA; IMMOBILIZATION; INSULIN BLOOD LEVEL; ISOLATED LIVER; KUPFFER CELL; LEUKOCYTE COUNT; LIPID DIET; LIPID PEROXIDATION; LIVER HISTOLOGY; LIVER NECROSIS; MALE; NONHUMAN; PORTAL VEIN; PRIORITY JOURNAL; RAT; SITTING; STATISTICAL SIGNIFICANCE; ANIMAL; BLOOD; CARBOHYDRATE DIET; DIET; DRUG EFFECT; ENZYMOLOGY; FAT INTAKE; IMMUNOHISTOCHEMISTRY; LIVER; MACROPHAGE; METABOLISM; PATHOLOGY; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WISTAR RAT;

ANIMALS; CORN OIL; DIET; DIETARY CARBOHYDRATES; DIETARY FATS; ENDOTOXEMIA; ENDOTOXINS; HEPATITIS; IMMUNOHISTOCHEMISTRY; INSULIN; LEUKOCYTE COUNT; LIPID PEROXIDATION; LIVER; MACROPHAGES; MALE; PHYSICAL CONDITIONING, ANIMAL; RATS; RATS, WISTAR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SUCROSE; TRANSAMINASES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 33644857704     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00229.2005     Document Type: Article

References (53)

1. Adachi Y, Moore LE, Bradford BU, Gao W, and Thurman RG. Antibiotics prevent liver injury in rats following long-term exposure to ethanol. Gastroenterology 108: 218-224, 1995.
2. Campfield LA, Smith FJ, and Burn P. The OB protein (leptin) pathway -a link between adipose tissue mass and central neural networks. Horm Metab Res 28: 619-632, 1996.
3. Canu MH and Falempin M. Effect of hindlimb unloading on locomotor strategy during treadmill locomotion in the rat. Eur J Appl Physiol Occup Physiol 74: 297-304, 1996.
4. Canu MH and Falempin M. Effect of hindlimb unloading on interlimb coordination during treadmill locomotion in the rat. Eur J Appl Physiol Occup Physiol 78: 509-515, 1998.
5. Chen H, Charlat O, Tartaglia LA, Woolf EA, Weng X, Ellis SJ, Lakey ND, Culpepper J, Moore KJ, Breitbart RE, Duyk GM, Tepper RI, and Morgenstern JP. Evidence that the diabetes gene encodes the leptin receptor: identification of a mutation in the leptin receptor gene in db/db mice. Cell 84: 491-495, 1996.
6. Das K and Kar P. Non-alcoholic steatohepatitis. J Assoc Physicians India 53: 195-199, 2005.
7. El Haschimi K, Pierroz DD, Hileman SM, Bjorbaek C, and Flier JS. Two defects contribute to hypothalamic leptin resistance in mice with diet-induced obesity. J Clin Invest 105: 1827-1832, 2000.
8. Fan CY, Pan J, Chu R, Lee D, Kluckman KD, Usuda N, Singh I, Yeldandi AV, Rao MS, Maeda N, and Reddy JK. Hepatocellular and hepatic peroxisomal alterations in mice with a disrupted peroxisomal fatty acyl-coenzyme A oxidase gene. J Biol Chem 271: 24698-24710, 1996.
9. Fan CY, Pan J, Chu R, Lee D, Kluckman KD, Usuda N, Singh I, Yeldandi AV, Rao MS, Maeda N, and Reddy JK. Targeted disruption of the peroxisomal fatty acyl-CoA oxidase gene: generation of a mouse model of pseudoneonatal adrenoleukodystrophy. Ann NY Acad Sci 804: 530-541, 1996.
10. Fan CY, Pan J, Usuda N, Yeldandi AV, Rao MS, and Reddy JK. Steatohepatitis, spontaneous peroxisome proliferation and liver tumors in mice lacking peroxisomal fatty acyl-CoA oxidase. Implications for peroxisome proliferator-activated receptor alpha natural ligand metabolism. J Biol Chem 273: 15639-15645, 1998.
11. Fiebig R, Griffiths MA, Gore MT, Baker DH, Oscai L, Ney DM, and Ji LL. Exercise training down-regulates hepatic lipogenic enzymes in meal-fed rats: fructose versus complex-carbohydrate diets. J Nutr 128: 810-817, 1998.
12. Goda T, Takase S, Yokogoshi H, Mita T, Isemura M, and Hoshi T. Changes in hepatic metabolism through simulated weightlessness: decrease of glycogen and increase of lipids following prolonged immobilization in the rat. Res Exp Med (Berl) 191: 189-199, 1991.
13. Hasty AH, Shimano H, Yahagi N, Amemiya-Kudo M, Perrey S, Yoshikawa T, Osuga J, Okazaki H, Tamura Y, Iizuka Y, Shionoiri F, Ohashi K, Harada K, Gotoda T, Nagai R, Ishibashi S, and Yamada N. Sterol regulatory element-binding protein-1 is regulated by glucose at the transcriptional level. J Biol Chem 275: 31069-31077, 2000.
14. Hu Y, Cardounel A, Gursoy E, Anderson P, and Kalimi M. Anti-stress effects of dehydroepiandrosterone: protection of rats against repeated immobilization stress-induced weight loss, glucocorticoid receptor production, and lipid peroxidation. Biochem Pharmacol 59: 753-762, 2000.
15. Kanda K, Omori S, Yamamoto C, Miyamoto N, Kawano S, Murata Y, Matsui N, and Seo H. Urinary excretion of stress hormones of rats in tail-suspension. Environ Med 37: 39-41, 1993.
16. Kawano S, Ohmori S, Kanda K, Ito T, Murata Y, and Seo H. Adrenocortical response to tail-suspension in young and old rats. Environ Med 38: 7-12, 1994.
17. Kelley GL, Allan G, and Azhar S. High dietary fructose induces a hepatic stress response resulting in cholesterol and lipid dysregulation. Endocrinology 145: 548-555, 2004.
18. Knox M, Fluckey JD, Bennett P, Peterson CA, and Dupont-Versteegden EE. Hindlimb unloading in adult rats using an alternative tail harness design. Aviat Space Environ Med 75: 692-696, 2004.
19. Lawler JM, Song W, and Demaree SR. Hindlimb unloading increases oxidative stress and disrupts antioxidant capacity in skeletal muscle. Free Radic Biol Med 35: 9-16, 2003.
20. Lieber CS, Leo MA, Mak KM, Xu Y, Cao Q, Ren C, Ponomarenko A, and DeCarli LM. Model of nonalcoholic steatohepatitis. Am J Clin Nutr 79: 502-509, 2004.
21. Liu MJ, Li JX, Guo HZ, Lee KM, Qin L, and Chan KM. The effects of verbascoside on plasma lipid peroxidation level and erythrocyte membrane fluidity during immobilization in rabbits: a time course study. Life Sci 73: 883-892, 2003.
22. Mantha L, Palacios E, and Deshaies Y. Modulation of triglyceride metabolism by glucocorticoids in diet-induced obesity. Am J Physiol Regul Integr Comp Physiol 277: R455-R464, 1999.
23. Marin P, Darin N, Amemiya T, Andersson B, Jern S, and Bjorntorp P. Cortisol secretion in relation to body fat distribution in obese premenopausal women. Metabolism 41: 882-886, 1992.
24. Michel RN and Gardiner PF. To what extent is hindlimb suspension a model of disuse? Muscle Nerve 13: 646-653, 1990.
25. Miyazaki M, Dobrzyn A, Man WC, Chu K, Sampath H, Kim HJ, and Ntambi JM. Stearoyl-CoA desaturase 1 gene expression is necessary for fructose-mediated induction of lipogenic gene expression by sterol regulatory element-binding protein-1c-dependent and -independent mechanisms. J Biol Chem 279: 25164-25171, 2004.
26. Musacchia XJ, Deavers DR, Meininger GA, and Davis TP. A model for hypokinesia: effects on muscle atrophy in the rat. J Appl Physiol 48: 479-486, 1980.
27. Musacchia XJ, Steffen JM, and Deavers DR. Rat hindlimb muscle responses to suspension hypokinesia/hypodynamia. Aviat Space Environ Med 54: 1015-1020, 1983.
28. Nanji AA and French SW. Dietary factors and alcoholic cirrhosis. Alcohol Clin Exp Res 10: 271-273, 1986.
29. Nanji AA and French SW. Dietary linoleic acid is required for development of experimentally induced alcoholic liver injury. Life Sci 44: 223-227, 1989.
30. Nanji AA, Khettry U, Sadrzadeh SM, and Yamanaka T. Severity of liver injury in experimental alcoholic liver disease. Correlation with plasma endotoxin, prostaglandin E2, leukotriene B4, and thromboxane B2. Am J Pathol 142: 367-373, 1993.
31. Nanji AA, Khwaja S, and Sadrzadeh SM. Eicosanoid production in experimental alcoholic liver disease is related to vitamin E levels and lipid peroxidation. Mol Cell Biochem 140: 85-89, 1994.
32. Nanji AA, Mendenhall CL, and French SW. Beef fat prevents alcoholic liver disease in the rat. Alcohol Clin Exp Res 13: 15-19, 1989.
33. Nanji AA, Sadrzadeh SM, and Dannenberg AJ. Liver microsomal fatty acid composition in ethanol-fed rats: effect of different dietary fats and relationship to liver injury. Alcohol Clin Exp Res 18: 1024-1028, 1994.
34. O'keefe MP, Perez FR, Kinnick TR, Tischler ME, and Henriksen EJ. Development of whole-body and skeletal muscle insulin resistance after one day of hindlimb suspension. Metabolism 53: 1215-1222, 2004.
35. Paterson JM, Morton NM, Fievet C, Kenyon CJ, Holmes MC, Staels B, Seckl JR, and Mullins JJ. Metabolic syndrome without obesity: Hepatic overexpression of 11beta-hydroxysteroid dehydrogenase type 1 in transgenic mice. Proc Natl Acad Sci USA 101: 7088-7093, 2004.
36. Ricart-Jane D, Rodriguez-Sureda V, Benavides A, Peinado-Onsurbe J, Lopez-Tejero MD, and Llobera M. Immobilization stress alters intermediate metabolism and circulating lipoproteins in the rat. Metabolism 51: 925-931, 2002.
37. Rivera CA, Bradford BU, Seabra V, and Thurman RG. Role of endotoxin in the hypermetabolic state after acute ethanol exposure. Am J Physiol Gastrointest Liver Physiol 275: G1252-G1258, 1998.
38. Rivera CA, Tcharmtchi MH, Mendoza L, and Smith CW. Endotoxemia and hepatic injury in a rodent model of hindlimb unloading. J Appl Physiol 95: 1656-1663, 2003.
39. Rosmond R. Role of stress in the pathogenesis of the metabolic syndrome. Psychoneuroendocrinology 30: 1-10, 2005.
40. Seckin S, Alptekin N, Dogru-Abbasoglu S, Kocak-Toker N, Toker G, and Uysal M. The effect of chronic stress on hepatic and gastric lipid peroxidation in long-term depletion of glutathione in rats. Pharmacol Res 36: 55-57, 1997.
41. Stuart CA, Kidder LS, Pietrzyk RA, Klein GL, and Simmons DJ. Rat tail suspension causes a decline in insulin receptors. Exp Toxicol Pathol 45: 291-295, 1993.
42. Sugino K, Dohi K, Yamada K, and Kawasaki T. The role of lipid peroxidation in endotoxin-induced hepatic damage and the protective effect of antioxidants. Surgery 101: 746-752, 1987.
43. Tou JC, Grindeland RE, and Wade CE. Effects of diet and exposure to hindlimb suspension on estrous cycling in Sprague-Dawley rats. Am J Physiol Endocrinol Metab 286: E425-E433, 2004.
44. Tsukamoto H, French SW, Benson N, Delgado G, Rao GA, Larkin EC, and Largman C. Severe and progressive steatosis and focal necrosis in rat liver induced by continuous intragastric infusion of ethanol and low fat diet. Hepatology 5: 224-232, 1985.
45. Vanderhoof JA, Metz MJ, Tuma DJ, Antonson DL, and Sorrell MF. Effect of improved absorption on development of jejunoileal bypass-induced liver dysfunction in rats. Dig Dis Sci 25: 581-586, 1980.
46. Vecchini A, Ceccarelli V, Orvietani P, Caligiana P, Susta F, Binaglia L, Nocentini G, Riccardi C, and Di Nardo P. Enhanced expression of hepatic lipogenic enzymes in an animal model of sedentariness. J Lipid Res 44: 696-704, 2003.
47. Vico L, Novikov VE, Very JM, and Alexandre C. Bone Histomorphometric compariso of rat tibial metaphysis after 7-day tail suspension vs. 7-day spaceflight. Aviat Space Environ Med 62: 26-31, 1991.
48. Wei M, Macera CA, Hornung CA, and Blair SN. Changes in lipids associated with change in regular exercise in free-living men. J Clin Epidemiol 50: 1137-1142, 1997.
49. Wigg AJ, Roberts-Thomson IC, Dymock RB, McCarthy PJ, Grose RH, and Cummins AG. The role of small intestinal bacterial overgrowth, intestinal permeability, endotoxaemia, and tumour necrosis factor alpha in the pathogenesis of non-alcoholic steatohepatitis. Gut 48: 206-211, 2001.
50. Wittwer M, Fluck M, Hoppeler H, Muller S, Desplanches D, and Billeter R. Prolonged unloading of rat soleus muscle causes distinct adaptations of the gene profile. FASEB J 16: 884-886, 2002.
51. Wronski TJ and Morey-Holton ER. Skeletal response to simulated weightlessness: a comparison of suspension techniques. Aviat Space Environ Med 58: 63-68, 1987.
52. Yahagi N, Shimano H, Hasty AH, Amemiya-Kudo M, Okazaki H, Tamura Y, Iizuka Y, Shionoiri F, Ohashi K, Osuga J, Harada K, Gotoda T, Nagai R, Ishibashi S, and Yamada N. A crucial role of sterol regulatory element-binding protein-1 in the regulation of lipogenic gene expression by polyunsaturated fatty acids. J Biol Chem 274: 35840-35844, 1999.
53. Yang SQ, Lin HZ, Lane MD, Clemens M, and Diehl AM. Obesity increases sensitivity to endotoxin liver injury: implications for the pathogenesis of steatohepatitis. Proc Natl Acad Sci USA 94: 2557-2562, 1997.