Enhancing patient outcomes in aesthetic and reconstructive breast surgery using triple antibiotic breast irrigation: Six-year prospective clinical study

Plastic and Reconstructive Surgery

Volumn 117, Issue 1, 2006, Pages 30-36

  Adams Jr , William P ^a   Rios, Jose L ^a   Smith, Sharon J ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

AMINOGLYCOSIDE ANTIBIOTIC AGENT; ANTIBIOTIC AGENT; BACITRACIN; CEFAZOLIN; CEPHALOSPORIN; GENTAMICIN; IODINE; PENICILLIN G; POVIDONE IODINE; SODIUM CHLORIDE; VANCOMYCIN; TOPICAL ANTIINFECTIVE AGENT;

AGED; ARTICLE; BREAST AUGMENTATION; BREAST ENDOPROSTHESIS; BREAST RECONSTRUCTION; CAREGIVER; CONTRACTURE; CONTROLLED STUDY; COST EFFECTIVENESS ANALYSIS; ESTHETIC SURGERY; FOLLOW UP; HUMAN; LAVAGE; MAJOR CLINICAL STUDY; POSTOPERATIVE INFECTION; PRIORITY JOURNAL; REOPERATION; ADOLESCENT; ADULT; ANTIBIOTIC PROPHYLAXIS; FEMALE; INFECTION; MICROBIOLOGY; MIDDLE AGED; PROSPECTIVE STUDY;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ANTI-INFECTIVE AGENTS, LOCAL; ANTIBIOTIC PROPHYLAXIS; BREAST IMPLANTATION; BREAST IMPLANTS; CONTRACTURE; FEMALE; HUMANS; IRRIGATION; MIDDLE AGED; POVIDONE-IODINE; PROSPECTIVE STUDIES; PROSTHESIS-RELATED INFECTIONS; REOPERATION;

EID: 33644854523     PISSN: 00321052     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.prs.0000185671.51993.7e     Document Type: Article

References (29)

1. Burkhardt, B. R., Fried, M., Schnur, P. L., and Tofield, J. J. Capsules, infection, and intraluminal antibiotics. Plast. Reconstr. Surg. 68: 43, 1981.
2. Mentor Corp. saline implant premarket approval. Available at www.fda.gov/cdrh/breastimplants/ 2000.
3. Inamed Corp. saline implant premarket approval. Available at www.fda.gov/cdrh/breastimplants/ 2000.
4. 2003 and 2005 silicone breast implant PMA information. Available at www.fda.gov/cdrh/breastimplants. Accessed September 2005.
5. Ahn, C. Y., Ko, C. Y., Wagar, E. A., Wong, R. S., and Shaw, W. W. Microbial evaluation: 139 implants removed from symptomatic patients. Plast. Reconstr. Surg. 98: 1225, 1996.
6. Burkhardt, B. R., Dempsey, P. D., Schnur, M. D., and Tofield, J. J. Capsular contracture: A prospective study of the effect of local antibacterial agents. Plast. Reconstr. Surg. 77: 919, 1986.
7. Dobke, M. K., Svahn, J. K., Vastine, V. L., Landon, B. N., Stein, P. C., and Parsons, C. L. Characterization of microbial presence at the surface of silicone mammary implants. Ann. Plast. Surg. 34: 563, 1995.
8. Netscher, D. T., Weizer, G., Wigoda, P., Walker, L. E., Thornby, J., and Bowen, D. Clinical relevance of positive breast peroprosthetic cultures without overt infection. Plast. Reconstr. Surg. 96: 1125, 1995.
9. Pajkos, A., Deva, A. K., Vickery, K., Cope, C., Chang, L., and Cossart, Y. E. Detection of subclinical infection in significant breast implant capsules. Plast. Reconstr. Surg. 111: 1605, 2003.
10. Shah, Z., Lehman, J. A., and Tan, J. Does infection play a role in breast capsular contracture? Plast. Reconstr. Surg. 68: 34, 1981.
11. Burkhardt, B. R., and Demas, C. P. The effect of Siltex texturing and povidone-iodine irrigation on capsular contracture around saline inflatable breast implants. Plast. Reconstr. Surg. 93: 123, 1994.
12. Burkhardt, B. R., and Eades, E. The effect of Biocell texturing and povidone-iodine irrigation on capsular contracture around saline-inflatable breast implants. Plast. Reconstr. Surg. 96: 1317, 1995.
13. Haiavy, J., and Tobin, H. Mycobacterium fortuitum infection in prosthetic breast implants. Plast. Reconstr. Surg. 109: 2124, 2002.
14. Adams, W. P., Jr., Conner, W. C. H., Barton, F. E., Jr., and Rohrich, R. J. Optimizing breast pocket irrigation: An in vitro study and clinical implications. Plast. Reconstr. Surg. 105: 334, 2000.
15. Adams, W. P., Jr., Conner, W. C. H., Barton, F. E., Jr., and Rohrich, R. J. Optimizing breast pocket irrigation: The post-betadine era. Plast. Reconstr. Surg. 107: 1596, 2001.
16. Burkhardt, B. R. Effects of povidone iodine on silicone gel implants in vitro: Implications for clinical practice (Discussion). Plast Reconstr Surg. 114: 711, 2004.
17. Tebbetts, J. B. A system for breast implant selection based on patient tissue characteristics and implant-soft-tissue dynamics. Plast. Reconstr. Surg. 109: 1396, 2002.
18. Tebbetts, J. B. Achieving a predictable 24-hour return to normal activities after breast augmentation: Part II. Patient preparation, refined surgical techniques, and instrumentation. Plast. Reconstr. Surg. 109: 293, 2002.
19. American Society of Plastic Surgeons Website, www.plasticsurgery.org.
20. Camirand, A., Doucet, J., and Harris, J. Breast augmentation: Compression: A very important factor in preventing capsular contracture. Plast. Reconstr. Surg. 104: 529, 1999.
21. Burkhardt, B. R. Capsular contracture: Hard breasts, soft data. Clin. Plas. Surg. 15: 521, 1988.
22. Bourgeois, F. J., Pinkerton, J. A., Andersen, W., and Thiagarajah, S. Antibiotic irrigation prophylaxis in the high-risk cesarean section patient. Am. J. Obstet. Gynecol. 153: 197, 1985.
23. Lord, J. W., LaRaja, R. D., Daliana, M., and Gordon, M. T. Prophylactic antibiotic wound irrigation in gastric, biliary, and colonic surgery. Am. J. Surg. 145: 209, 1983.
24. Busin, M. Antibiotic irrigation of the capsular bag to resolve low-grade endophthalmitis. Cat. Refrac. Surg. 222: 385, 1996.
25. Dirschl, D. R., and Wilson, F. C. Topical antibiotic irrigation in the prophylaxis of operative wound infections in orthopedic surgery. Orthop. Clin. North Am. 22: 419, 1991.
26. Nelson, K. J., Gallup, D. G., Gibbs, R., and Paulk, W. Intraoperative antibiotic irrigation as prophylaxis in abdominal hysterectomy: A preliminary report. South. Med. J. 77: 700, 1984.
27. Brandon, H. J., Young, V. L., Jerina, K. L., et al. Mechanical analysis of explanted saline filled breast implants exposed to betadine pocket irrigation. Aesthetic Surg. J. 22: 438, 2002.
28. Zambacos, G. J., Nguyen, D., and Morris, R. J. Effects of povidone iodine on silicone gel implants in vitro: Implications for clinical practice. Plast. Reconstr. Surg. 114: 706, 2004.
29. Darouiche, R. O., Meade, R., Mansouri, M. D., and Netscher, D. T. In vivo efficacy of antimicrobe-impregnated saline-filled silicone implants. Plast. Reconstr. Surg. 109: 1352, 2002.