Intralesional bleomycin for the treatment of hemangiomas

Plastic and Reconstructive Surgery

Volumn 117, Issue 1, 2006, Pages 221-226

  Pienaar, Conrad ^a   Graham, Roger ^a   Geldenhuys, Stuart ^a   Hudson, Don A ^a,b  

^a UNIVERSITY OF CAPE TOWN   (South Africa)

^b UNIVERSITY OF CAPE TOWN   (South Africa)

Author keywords

[No Author keywords available]

Indexed keywords

BLEOMYCIN; ANTINEOPLASTIC ANTIBIOTIC;

ARTICLE; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; FEMALE; FOLLOW UP; HEMANGIOMA; HUMAN; HYPERPIGMENTATION; INFANT; MALE; OUTCOME ASSESSMENT; PRIORITY JOURNAL; TEACHING HOSPITAL; HAND; HEAD AND NECK TUMOR; INTRALESIONAL DRUG ADMINISTRATION; LIP TUMOR; NOSE TUMOR; PRESCHOOL CHILD; RETREATMENT;

ANTIBIOTICS, ANTINEOPLASTIC; BLEOMYCIN; CHILD; CHILD, PRESCHOOL; FEMALE; HAND; HEAD AND NECK NEOPLASMS; HEMANGIOMA; HUMANS; INFANT; INJECTIONS, INTRALESIONAL; LIP NEOPLASMS; MALE; NOSE NEOPLASMS; RETREATMENT;

EID: 33644850855     PISSN: 00321052     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.prs.0000194906.61805.b0     Document Type: Article

References (19)

1. Gampper, T. J., and Morgan, R. F. Vascular anomalies: Hemangiomas. Plast. Reconstr. Surg. 110: 572, 2002.
2. Mulliken, J. B., and Glowacki, J. Hemangiomas and vascular malformations in infants and children: A classification based on endothelial characteristics. Plast. Reconstr. Surg. 69: 412,1982.
3. Drolet, B. A., Esterly, N. B., and Frieden, I. J. Hemangiomas in children. N. Engl. J. Med. 341: 173, 1999.
4. Mulliken, J. B. Vascular anomalies. In S. Aston (Ed.), Grabb and Smith's Plastic Surgery. 5th Ed. Philadelphia: Lippincott-Raven, 1997.
5. Zide, B. M., Glat, P. M., Stile, F. L., and Longaker, M. T. Vascular lip enlargement: Part I. Hemangiomas: Tenets of therapy. Plast. Reconstr. Surg. 100: 1664, 1997.
6. Denk, M. J., Ajkay, N., Yuan, X., Rosenblum, R. S., Freda, N., and Magee, W. P. Surgical treatment of nasal hemangiomas. Ann. Plast. Surg. 48: 489, 2002.
7. Warren, S. M., Longaker, M. T., and Zide, B. M. The subunit approach to nasal tip hemangiomas. Plast. Reconstr. Surg. 109: 25, 2002.
8. Edgerton, M. The treatment of hemangiomas: With special reference to the role of steroid therapy. Ann. Surg. 183: 517, 1976.
9. Enjolras, O., Riche, M. C., Merland, J. J., and Escande, J. P. Management of alarming hemangiomas in infancy: A review of 25 cases. Pediatrics 85: 491, 1990.
10. Achauer, B. M., Chang, C.-J., Vander, M., and Kam, V. Management of hemangioma of infancy: Review of 245 patients. Plast. Reconstr. Surg. 99: 1301, 1997.
11. Scheepers, J. H., and Quaba, A. A. Does the pulsed tunable dye laser have a role in the management of infantile haemangiomas? Observations based on 3 years' experience. Plast. Reconstr. Surg. 95: 305, 1995.
12. Mulliken, J. B., Rogers, G. F., and Marler, J. J. Circular excision of hemangioma and purse string-closure: The smallest possible scar. Plast. Reconstr. Surg. 109: 1544, 2002.
13. Reinisch, J. F., Kim, R. Y., Harshbarger, R. J., and Meara, J. G. Surgical management of parotid haemangioma. Plast. Reconstr. Surg. 113: 1940, 2004.
14. Tanigawa, N., Shimomatsuya, T., Takahashi, K., et al. Treatment of cystic hygroma and lymphangioma with the use of bleomycin fat emulsion. Cancer 60: 741, 1987.
15. Qin, Z. P., Xin, Z. F., Ren, L., Liu, X. J., Yao, S. G., and Linyi, S. Long term results of intratumorous bleomycin: A5 injection for head and neck lymphangioma. Oral Surg. Oral Med. Oral Pathol. 86: 139, 1998.
16. Orford, J., Barker, A., Thonell, S., King, P., and Murphy, J. Bleomycin therapy for cystic hygroma. J. Pediatr. Surg. 30: 1282, 1995.
17. Okada, A., Kubota, A., Fukuzawa, M., and Imura, K. Injection of bleomycin as a primary therapy of cystic lymphangioma. J. Pediatr. Surg. 27: 440, 1992.
18. Kullendorff, C. M. Efficacy of bleomycin treatment for symptomatic hemangiomas in children. Pediatr. Surg. Int. 12: 526, 1997.
19. Sarihan, H., Mocan, H., Yildiz, K., Abes, M., and Akyazia, A. A new treatment with bleomycin for complicated cutaneous haemangioma in children. Eur. J. Pediatr. Surg. 7: 158, 1997.