Atrial natriuretic peptide has dose-dependent, autonomically mediated effects on atrial refractoriness and repolarization in anesthetized dogs

Journal of Cardiovascular Electrophysiology

Volumn 16, Issue 12, 2005, Pages 1341-1347

  Stambler, Bruce S ^a,b   Guo, Gary B ^a  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b UNIVERSITY HOSPITALS OF CLEVELAND   (United States)

Author keywords

Action potentials; Atrial fibrillation; Autonomic; Electrophysiology; Natriuretic peptides; Nervous system; Refractory period

Indexed keywords

ACETYLCHOLINE; ATRIAL NATRIURETIC FACTOR; ATROPINE; AURICULIN; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CHLORALOSE; ISOPRENALINE; PROPRANOLOL;

ACTION POTENTIAL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARRHYTHMOGENESIS; ARTICLE; AUTONOMIC NERVOUS SYSTEM; BETA ADRENERGIC RECEPTOR BLOCKING; CONTROLLED STUDY; DOG; DOSE RESPONSE; DRUG INFUSION; ELECTROPHYSIOLOGY; HEART ATRIUM FIBRILLATION; HEART ATRIUM PACING; HEART REPOLARIZATION; HEART RIGHT ATRIUM PRESSURE; HEMODYNAMICS; MEAN ARTERIAL PRESSURE; NONHUMAN; PRIORITY JOURNAL; REFRACTORY PERIOD; VAGUS NERVE STIMULATION; ANIMAL; DRUG EFFECT; HEART ATRIUM; HEART ATRIUM FUNCTION; HEART FUNCTION TEST; PATHOPHYSIOLOGY; PHYSIOLOGY;

ACTION POTENTIALS; ANIMALS; ATRIAL FIBRILLATION; ATRIAL FUNCTION; ATRIAL NATRIURETIC FACTOR; DOGS; ELECTROPHYSIOLOGIC TECHNIQUES, CARDIAC; HEART ATRIA; HEMODYNAMIC PROCESSES; MODELS, ANIMAL;

EID: 33644849029     PISSN: 10453873     EISSN: 15408167     Source Type: Journal    
DOI: 10.1111/j.1540-8167.2005.00259.x     Document Type: Article

References (36)

1. Clemo HF Baumgarten CM Stambler BS Wood MA Ellenbogen KA: Atrial natriuretic factor: Implications for cardiac pacing and electrophysiology. Pacing Clin Electrophysiol 1994 17: 70 91.
2. Clemo HF Baumgarten CM Ellenbogen KA Stambler BS: Atrial natriuretic peptide and cardiac electrophysiology: Autonomic and direct effects. J Cardiovasc Electrophysiol 1996 7: 149 162.
3. Hansson M: Natriuretic peptides in relation to the cardiac innervation and conduction system. Microsc Res Tech 2002 58: 378 386.
4. Burnett JC Jr. Kao PC Hu DC Heser DC Heublein D Granger JP Opgenorth TJ Reeder GS: Atrial natriuretic peptide elevation in congestive heart failure in the human. Science 1986 231: 1145 1147.
5. Roy D Paillard F Cassidy D Bourassa MG Gutkowska J Genest J Cantin M: Atrial natriuretic factor during atrial fibrillation and supraventricular tachycardia. J Am Coll Cardiol 1987 9: 509 514.
6. Sorbera LA Morad M: Atrionatriuretic peptide transforms cardiac sodium channels into calcium conducting channels. Science 1990 247: 969 973.
7. Le Grand B Deroubaix E Couetil JP Coraboeuf E: Effects of atrionatriuretic factor on Ca2+ current and Ca-independent transient outward K+ current in human atrial cells. Pflugers Arch 1992 421: 486 491.
8. Bkaily G Perron N Wang S Sculptoreanu A Jacques D Menard D: Atrial natriuretic factor blocks the high-threshold Ca2+ current and increases K+ current in fetal single ventricular cells. J Mol Cell Cardiol 1993 25: 1305 1316.
9. Tohse N Nakaya H Takeda Y Kanno M: Cyclic GMP-mediated inhibition of L-type Ca2+ channel activity by human natriuretic peptide in rabbit heart cells. Br J Pharmacol 1995 114: 1076 1082.
10. Thoren P Mark AL Morgan DA O'Neill TP Needleman P Brody MJ: Activation of vagal depressor reflexes by atriopeptins inhibits renal sympathetic nerve activity. Am J Physiol 1986 251: H1252 H1259.
11. Holtz J Sommer O Bassenge E: Inhibition of sympathoadrenal activity by atrial natriuretic factor in dogs. Hypertension 1987 9: 350 354.
12. Ebert TJ: Reflex activation of sympathetic nervous system by ANF in humans. Am J Physiol 1988 255: H685 H689.
13. Ackermann U Khanna J Irizawa TG: Atrial natriuretic factor alters autonomic interactions in the control of heart rate in conscious rats. Can J Physiol Pharmacol 1988 66: 930 936.
14. Roach PJ Sanders JS Berg W Mark AL Ebert TJ Ferguson DW: Pathophysiologic levels of atrial natriuretic factor do not alter reflex sympathetic control: Direct evidence from microneurographic studies in humans. J Am Coll Cardiol 1990 15: 1318 1330.
15. Floras JS: Sympathoinhibitory effects of atrial natriuretic factor in normal humans. Circulation 1990 81: 1860 1873.
16. Atchison DJ Ackermann U: Influence of atrial natriuretic factor on autonomic control of heart rate. Am J Physiol Regul Integr Comp Physiol 1990 258: R718 R723.
17. Atchison DJ Pennefather PS Ackermann U: ANP has no postsynaptic effect on autonomic regulation of cardiac pacemaker rate in the rat. Am J Physiol 1993 265: H1983 H1987.
18. Butler GC Senn BL Floras JS: Influence of atrial natriuretic factor on heart rate variability in normal men. Am J Physiol 1994 267: H500 H505.
19. Koyama S Nishida Y Hosomi H Abe Y: Participation of baroreceptors reflexes in blood pressure and sympathetic nerve responses to a synthetic human atrial natriuretic peptide in anesthetized dogs. Eur J Pharmacol 1986 127: 43 48.
20. Zimmerman RS Schirger JA Edwards BS Schwab TR Heublein DM Burnett JC Jr.: Cardio-renal-endocrine dynamics during stepwise infusion of physiologic and pharmacologic concentrations of atrial natriuretic factor in the dog. Circ Res 1987 61: 63 69.
21. Crozier I Richards AM Foy SG Ikram H: Electrophysiological effects of atrial natriuretic peptide on the cardiac conduction system in man. Pacing Clin Electrophysiol 1993 16: 738 742.
22. Wijffels MCEF Kirchhof CJHJ Dorland R Power J Allessie MA: Electrical remodeling due to atrial fibrillation in chronically instrumented conscious goats: Roles of neurohumoral changes, ischemia, atrial stretch, and high rate of electrical activation. Circulation 1997 96: 3710 3720.
23. Murakawa Y Yamashita T Kanese Y Omata M: Effect of atrial natriuretic peptide on electrical defibrillation efficacy. J Cardiovasc Electrophysiol 1998 9: 962 969.
24. Kecskemeti V Pacher P Pankucsi C Nanasi P: Comparative study of cardiac electrophysiological effects of atrial natriuretic peptide. Mol Cell Biochem 1996 160161: 53 59.
25. Yang JM Yang SN Lin CI: The electrophysiological and mechanical effects of atrial natriuretic peptide and acetylcholine on guinea pig ventricular papillary muscle. Proc Natl Sci Counc Repub China B 1989 13: 289 297.
26. Lambert C Ribuot C Robichaud A Cusson JR: Negative chronotropic effect of the atrial natriuretic peptide in an anaesthetized dog model. Eur J Pharmacol 1994 252: 245 252.
27. Cox R: Influence of chloralose anesthesia on cardiovascular function in trained dogs. Am J Physiol 1972 223: 660 667.
28. Nattel S Wang ZG Matthews C: Direct electrophysiological actions of pentobarbital at concentrations achieved during general anesthesia. Am J Physiol 1990 259: H1743 H1751.
29. Euler DE Scanlon PJ: Acetylcholine release by a stimulus train lowers atrial fibrillation threshold. Am J Physiol 1987 253: H863 H868.
30. Sheets MF Hanck DA: Atrionatriuretic peptide and calcium-conducting sodium channels. Science 1991 252: 449 452.
31. Zipes DR Mihalick MJ Robbins GT: Effects of selective vagal and stellate ganglion stimulation on atrial refractoriness. Cardiovasc Res 1974 8: 647 655.
32. Ebert TJ Cowley AW Jr.: Atrial natriuretic factor attenuates carotid baroreflex-mediated cardioacceleration in humans. Am J Physiol 1988 254 ( 4 Pt 2 R590 R594.
33. Ferrari P Ferrier CP Franscini L Saxenhofer H Shaw S Weidmann P: Atrial natriuretic factor and autonomic nervous system function in man. Eur J Clin Pharmacol 1990 38: 25 30.
34. Rensma PL Allessie MA Lammers WJEP Bonke FIM Schalij MJ: Length of excitation wave and susceptibility to reentrant atrial arrhythmias in normal conscious dogs. Circ Res 1988 62: 395 410.
35. Liu L Nattel S: Differing sympathetic and vagal effects on atrial fibrillation in dogs: Role of refractoriness heterogeneity. Am J Physiol 1997 42: H805 H816.
36. Morishita Y Sano T Ando K Saitoh Y Kase H Yamada K Matsuda Y: Microbial polysaccharide, HS-142-1, competitively and selectively inhibits ANP binding to its guanylyl cyclase-containing receptor. Biochem Biophys Res Commun 1991 176: 949 957.