Is there a real alternative anticoagulant to heparin in continuous treatments?

Expert Review of Medical Devices

Volumn 3, Issue 1, 2006, Pages 5-8

  Mariano, Filippo ^a   Tetta, Ciro ^b   Ronco, Claudio ^c   Triolo, Giorgio ^a  

^a CTO HOSPITAL   (Italy)

^b FRESENIUS MEDICAL CARE   (Germany)

^c SAN BORTOLO HOSPITAL   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ANTICOAGULANT AGENT; BICARBONATE; CALCIUM; CALCIUM ION; CITRATE TRISODIUM; CITRIC ACID; HEPARIN; HIRUDIN; LOW MOLECULAR WEIGHT HEPARIN; NAFAMSTAT; PROSTACYCLIN; SERINE PROTEINASE INHIBITOR;

ACUTE KIDNEY FAILURE; ANTICOAGULATION; BLEEDING DISORDER; CLINICAL TRIAL; CONTINUOUS RENAL REPLACEMENT THERAPY; DEEP VEIN THROMBOSIS; DRUG METABOLISM; EDITORIAL; EXTRACORPOREAL CIRCULATION; HEMODIALYSIS; HUMAN; HYPERNATREMIA; HYPOCALCEMIA; INTENSIVE CARE UNIT; METABOLIC ALKALOSIS; METABOLIC DISORDER; NEPHROLOGY; SURVIVAL RATE; DRUG ADMINISTRATION; KIDNEY DISEASE; RENAL REPLACEMENT THERAPY;

ANTICOAGULANTS; CITRATES; DRUG ADMINISTRATION SCHEDULE; HEPARIN; HUMANS; KIDNEY DISEASES; RENAL DIALYSIS;

EID: 33644847290     PISSN: 17434440     EISSN: 17452422     Source Type: Journal    
DOI: 10.1586/17434440.3.1.5     Document Type: Editorial

References (14)

1. Haas G. Ueber blutwaschung. Klin. Wochenschr. 7, 1356-1362 (1928).
2. Geerts WFL Pineo GF, Heit JA et al. Prevention of venous thromboembolism: the seventh ACCP conference on antithrombotic and thrombolytic therapy. Chest 126(3 Suppl.) S338-S400 (2004).
3. van de Wetering J, Westendorp RG, van der Hoeven JG et al. Heparin use in continuous. renal replacement procedures: the struggle between filter coagulation and patient hemorrhage. J. Am. Soc. Nephrol. 7, 145-150 (1996).
4. Martin PY, Chevrolet JC, Suter P, Favre H. Anticoagulation in patients treated by continuous venovenous hemofiltration: a retrospective study. Am. J. Kidney Dis. 24, 806-812 (1994).
5. Gabutti L, Marone C, Colucci G, Duchini F, Schonholzer C. Citrate anticoagulation in continuous venovenous hemodiafiltration: a metabolic challenge. Intensive Care Med. 28, 1419-1425 (2002).
6. Morita Y, Johnson RW, Dom RE, Hall DS. Regional and coagulation during hemodialysis using citrate. Am. J. Med, Sci. 242, 32-43 (1961).
7. Mehta RL, McDonald BR, Aguilar MM, Ward DM. Regional citrate anticoagulation for continuous arteriovenous hemodialysis in critically ill patients. Kidney Int. 38, 976-981 (1990).
8. Bagshaw SM, Laupland KB, Boiteau PJ, Godinez-Luna T. Is regional citrate superior to systemic heparin anticoagulation for continuous renal replacement therapy? A prospective observational study in an adult regional critical care system. J. Crit. Care 20, 155-161 (2005).
9. Hyman A, Mendelsshon DC. Current dialysis approaches to dialysis for acute renal failure, in the ICU. Am. J. Nephrol. 22, 29-34 (2002).
10. Monchi M, Berghmans D, Ledoux D, Canivet JL, Dubois B, Damas P. Citrate vs. heparin for anticoagulation in continuous venovenous hemofiltration: a prospective randomized study. Intensive Care Med. 30, 260-265 (2004).
11. Mariano F, Tetta C, Stella M, Biolino P. Miletto A, Triolo G. Regional citrate anticoagulation in critically ill patients treated by plasma filtration and adsorption. Blood Purif 22, 313-319 (2004).
12. Kutsogiannis DJ, Cibney RTN, Stollery D, Gao J. Regional citrate versus systemic heparin anticoagulation for continuous renal replacement in critically ill patients. Kidney Int, 67, 2361-2367 (2005).
13. Brophy PD, Somers MJ, Baum MA et al. Multi-center evaluation of anticoagulation in patients receiving continuous renal replacement therapy (CRRT). Nephrol. Dial. Transplant. 20, 1416-1421 (2005).
14. Morgera S, Haase M, Rückert M et al. Regional citrate anticoagulatlon in continuous hemodialysis - acid-base and electrolyte balance at an increased dose of dialysis. Nephron. Clin. Prac. 101, C211-C219 (2005).