Entropy Rectifies the Brownian Steps of Kinesin

Nature Chemical Biology

Volumn 1, Issue 6, 2005, Pages 342-347

  Taniguchi, Yuichi ^a,b   Nishiyama, Masayoshi ^c   Ishii, Yoshiharu ^a   Yanagida, Toshio ^a,b,d  

^a JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^b OSAKA UNIVERSITY   (Japan)

^c KYOTO UNIVERSITY   (Japan)

^d OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

KINESIN; MOLECULAR MOTOR;

ANIMAL; ARTICLE; CATTLE; CHEMISTRY; ENTROPY; KINETICS; MECHANICS; METABOLISM; MICROTUBULE; TIME;

ANIMALS; CATTLE; ENTROPY; KINESIN; KINETICS; MECHANICS; MICROTUBULES; MOLECULAR MOTOR PROTEINS; TIME FACTORS;

EID: 33644842607     PISSN: 15524450     EISSN: 15524469     Source Type: Journal    
DOI: 10.1038/nchembio741     Document Type: Article

References (44)

1. Vale, R.D. & Milligan, R.A. The way things move: looking under the hood of molecular motor proteins. Science 288, 88-95 (2000).
2. Howard, J. Molecular motors: structural adaptations to cellular functions. Nature 389, 561-567 (1997).
3. Cross, R.A. The kinetic mechanism of kinesin. Trends Biochem. Sci. 29, 301-309 (2004).
4. Endow, S. Kinesin motors as molecular machines. Bioessays 25, 1212-1219 (2003).
5. Svoboda, K., Schmidt, C.F., Schnapp, B.J. & Block, S.M. Direct observation of kinesin stepping by optical trapping interferometry. Nature 365, 721-727 (1993).
6. Carter, N.J. & Cross, R.A. Mechanics of the kinesin step. Nature 435, 308-312 (2005).
7. Hua, W., Young, E.C., Fleming, M.L. & Gelles, J. Coupling of kinesin steps to ATP hydrolysis. Nature 388, 390-393 (1997).
8. Schnitzer, M.J. & Block, S.M. Kinesin hydrolyses one ATP per 8-nm step. Nature 388, 386-390 (1997).
9. Nishiyama, M., Higuchi, H. & Yanagida, T. Chemomechanical coupling of the forward and backward steps of single kinesin molecules. Nat. Cell Biol. 4, 790-797 (2002).
10. Hackney, D.D. Evidence for alternating head catalysis by kinesin during microtubule-stimulated ATP hydrolysis. Proc. Natl. Acad. Sci. USA 91, 6865-6869 (1994).
11. Kaseda, K., Higuchi, H. & Hirose, K. Alternate fast and slow stepping of a hetero-dimeric kinesin molecule. Nat. Cell Biol. 5, 1079-1082 (2003).
12. Yildiz, A., Tomishige, M., Vale, R.D. & Selvin, P.R. Kinesin walks hand-over-hand. Science 303, 676-678 (2004).
13. Asbury, C.L., Fehr, A.N. & Block, S.M. Kinesin moves by an asymmetric hand-over-hand mechanism. Science 302, 2130-2134 (2003).
14. Case, R.B., Pierce, D.W., Hom-Booher, N., Hart, C.L. & Vale, R.D. The directional preference of kinesin motors is specified by an element outside of the motor catalytic domain. Cell 90, 959-966 (1997).
15. Rice, S. et al. A structural change in the kinesin motor protein that drives motility. Nature 402, 778-784 (1999).
16. Rice, S. et al. Thermodynamic properties of the kinesin neck-region docking to the catalytic core. Biophys. J. 84, 1844-1854 (2003).
17. Schnitzer, M.J., Visscher, K. & Block, S.M. Force production by single kinesin motors. Nat. Cell Biol. 2, 718-723 (2000).
18. Block, S.M., Asbury, C.L., Shaevitz, J.W. & Lang, M.J. Probing the kinesin reaction cycle with a 2D optical force clamp. Proc. Natl. Acad. Sci. USA 100, 2351-2356 (2003).
19. Wang, M. et al. Force and velocity measured for single molecules of RNA polymerase. Science 282, 902-907 (1998).
20. Mazumdar, M. & Cross, R.A. Engineering a lever into the kinesin neck. J. Biol. Chem. 273, 29352-29359 (1998).
21. Eyring, H. The activated complex in chemical reactions. J. Chem. Phys. 3, 107-115 (1935).
22. Atkins, P.W. Physical Chemistry 3rd edn. Ch. 30, 737-761 (Oxford University Press, Oxford, UK, 1987).
23. Yang, W.Y. & Gruebele, M. Folding at the speed limit. Nature 423, 193-197 (2003).
24. Kojima, H., Muto, E., Higuchi, H. & Yanagida, T. Mechanics of single kinesin molecules measured by optical trapping nanometry. Biophys. J. 73, 2012-2022 (1997).
25. Nishiyama, M. et al. Substeps within the 8-nm step of the ATPase cycle of single kinesin molecules. Nat. Cell Biol. 3, 425-428 (2001).
26. Kawaguchi, K. & Ishiwata, S. Temperature dependence of force, velocity, and processivity of single kinesin molecules. Biochem. Biophys. Res. Commun. 272, 895-899 (2000).
27. Nishiyama, M., Higuchi, H., Ishii, Y., Taniguchi, Y. & Yanagida, T. Single molecule processes onthe stepwise movement of ATP-driven molecularmotors. Biosystems 71, 145-156 (2003).
28. Bohm, K. et al. Effectof temperatureon kinesin-driven microtubuleglidingand kinesin ATPase activity. FEBS Lett. 466, 59-62 (2000).
29. Kawaguchi, K. & Ishiwata, S. Thermal activation of single kinesin molecules with temperature pulse microscopy. Cell Motil. Cytoskeleton 49, 41-47 (2001).
30. Fersht, A.R. Structure and Mechanism in Protein Science (W.H. Freeman, New York, 1999).
31. Hirose, K., Lockhart, A., Cross, R.A. & Amos, L.A. Three-dimensional cytoelectron microscopy of dimeric kinesin and ncd motor domains on microtubules. Proc. Natl. Acad. Sci. USA 93, 9539-9544 (1996).
32. Hirose, K., Lowe, J., Alonso, M., Cross, R.A. & Amos, L.A. Congruent docking of dimeric kinesin and ncd into three-dimensional electron cryomicroscopy maps of microtubule-motor ADP complexes. Mol. Biol. Cell 10, 2063-2074 (1999).
33. Mandelkow, E. & Hoenger, A. Structures of kinesin and kinesin-microtubule interactions. Curr. Opin. Cell Biol. 11, 34-44 (1999).
34. Uemura, S. & Ishiwata, S. Loading direction regulates the affinity of ADP for kinesin. Nat. Struct. Biol. 10, 308-311 (2003).
35. Kawaguchi, K., Uemura, S. & Ishiwata, S. Equilibrium and transition between single-and double-headed binding of kinesin as revealed by single-molecule mechanics.Biophys. J. 84, 1103-1113 (2003).
36. Ali, M.Y. et al. Unconstrained steps of myosin VI appear longest among known molecular motors. Biophys. J. 86, 3804-3810 (2004).
37. Kitamura, K., Tokunaga, M., Esaki, S., Iwane, A.H. & Yanagida, T. Mechanism of muscle contraction based on stochastic properties of single actomyosin motors observed in vitro. Biophysics 1, 1-19(2005).
38. Svoboda, K. & Block, S.M. Force and velocity measured for single kinesin molecules. Cell 77, 773-784 (1994).
39. William, H.P., Saul, A.T., William, T.V. & Brian, P.F. Numerical Recipes in C 2nd edn. (Cambridge University Press, New York, 1992).
40. Rief, M. et al. Myosin-V stepping kinetics: a molecular model for processivity. Proc. Natl. Acad. Sci. USA 97, 9482-9486 (2000).
41. Altman, D., Sweeney, H.L. & Spudich, J.A. The mechanism of myosin VI translocation and its load-induced anchoring. Cell 116, 737-749 (2004).
42. Howard, J. Mechanics of Motor Proteins and the Cytoskeleton (Sinauer Associates, Sunderland, Massachusetts, 2001).
43. Kull, F.J. et al. Crystal structure of the kinesin motor domain reveals a structural similarity to myosin. Nature 380, 550-555 (1996).
44. Tadakuma, H., Yamaguchi, J., Ishihara, Y. & Funatsu, T. Imaging of single fluorescent molecules using video-rate confocal microscopy. Biochem. Biophys. Res. Commun. 287, 323-327 (2001).