Unclassified rhabdomyosarcoma in a patient with anti-Hu syndrome

Acta Clinica Belgica

Volumn 60, Issue 5, 2005, Pages 248-251

  Schilstra, Alexandra ^a,b   Van Tuijl, J H ^a   Van Suylen, R J ^a   Faber, C G ^a   Ten Velde, G P M ^a  

^a MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

^b ANTWERP UNIVERSITY HOSPITAL   (Belgium)

Author keywords

Anti Hu syndrome; Rhabdomyosarcoma; SCLC

Indexed keywords

CD56 ANTIGEN; DESMIN; FLUORODEOXYGLUCOSE; HU ANTIBODY; MYOGENIC FACTOR; MYOGENIC FACTOR 4; UNCLASSIFIED DRUG; HU ANTIGEN;

ABDOMINAL PAIN; AGED; ANISOCORIA; ANTI HU SYNDROME; ARTICLE; ATAXIA; AUTOIMMUNE DISEASE; CASE REPORT; CELL DIFFERENTIATION; CELL STRUCTURE; CLINICAL FEATURE; COMPUTER ASSISTED TOMOGRAPHY; DEATH; DISEASE ASSOCIATION; DYSARTHRIA; ELECTROMYOGRAPHY; ENDOSCOPIC SURGERY; HEARTBURN; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; NETHERLANDS; NUCLEAR MAGNETIC RESONANCE IMAGING; PARANEOPLASTIC NEUROPATHY; PHYSICAL EXAMINATION; POSITRON EMISSION TOMOGRAPHY; RHABDOMYOSARCOMA; SENSORIMOTOR NEUROPATHY; SPEECH DISORDER; SYMPTOM; THORACOSCOPY; IMMUNOLOGY; PATHOLOGY; THORAX TUMOR;

AGED; HU PARANEOPLASTIC ENCEPHALOMYELITIS ANTIGENS; HUMANS; MALE; PARANEOPLASTIC POLYNEUROPATHY; RHABDOMYOSARCOMA; THORACIC NEOPLASMS;

EID: 33644831901     PISSN: 00015512     EISSN: None     Source Type: Journal    
DOI: 10.1179/acb.2005.040     Document Type: Article

References (16)

1. Graus F, Keime - Guibert F, Rene R, Benyahia B, Ribalta T, Ascaso C, Escaramis G, Delattre JY. Anti-Hu-associated para-neoplastic encephalomyelitis: analysis of 200 patients. Brain 2001; 124: 1138-48
2. Dalmau J, Graus F, Rosenblum MK, Posner JB. Anti-Hu-associated paraneoplastic encephalomyelitis/sensory neuropathy: a clinical study of 71 patients. Medicine 1992; 71: 59-72
3. 18F] fluorodeoxyglucose positron emission tomography in the diagnosis of cancer in patients with paraneoplastic neurological syndrome and anti-Hu antibodies. Ann Neurol 2000; 48: 105-8
4. Moll JW, Antoine JC, Brashear HR, Delattre J, Drlicek M, Dropcho FJ. Guidelines on the detection of paraneoplastic anti-neuronal-specific antibodies: report from the Workshop to the fourth Meeting of the International Society of Neuro-Immunology on paraneoplastic neurological disease, held October 22-23, 1994 in Rotterdam, The Netherlands, Neurology 1994; 44: 1937-41
5. Voltz R, Dalmau J, Posner JB, Rosenfeld MR. T-cell receptor analysis in anti- Hu associated paraneoplastic encephalomyelitis. Neurology 1998; 51: 1146-50
6. Gultekin SH, Rosai J, Demopoulos A, Graus YF, Posner JB, Dalmau J, et al. Hu immunolabeling as a marker of neural and neuroendocrine differentiation in normal and neoplastic human tissues: assessment using a recombinant anti-Hu Fab fragment. Int J Surg Pathol 2000; 8: 109-17
7. Crist W, Gehan EA, Ragab AH, Dickman PS, Donaldson SS, Fryer C, et al. The Third Intergroup Rhabdomyosarcoma Study. J Clin Oncol 1995: 13: 610-30
8. Coindre JM. Immunohistochemistry in the diagnosis of soft tissue tumours. Histopathol 2003; 43: 1-16
9. Luchinetti CF, Kimmel DW, Lennon VA. Paraneoplastic and oncologic profiles of patients seropositive for type 1 antineuronal nuclear autoantibodies. Neurology 1998; 50: 652-7
10. Musunuru K, Darnell RB. Paraneoplastic neurologic disease antigens: RNA- binding proteins and signalling proteins in neuronal degeneration. Annu Rev Neurosci 2001; 24: 239-62
11. Masami T, Yoshie M, Miha S, Hitoshi M, Keiko K, Keiko T. Cytotoxic T cell activity against peptides of Hu protein in anti-Hu syndrome. J Neurol Sciences 2002; 201: 9-12
12. Camdessanché JP, Antoine JC, Honnorat J, Vial C, Petiot P, Convers P, et al. Paraneoplastic peripheral neuropathy associated with anti-Hu antibodies. Brain 2002; 125: 166-75
13. Oh Sj, Gürtekin Y, Dropcho EJ, King P, Claussen GC. Anti-Hu antibody neuropathy: a clinical, electrophysiological, and pathological study. Clin Neurophysiol 2005; 116: 28-34
14. De Giorgio R, Bovara M, Barbara G, Canossa M, Sarnelli G, De Pont Stanghellini V. Anti-HuD-induced neuronal apoptosis underlying paraneoplastic gut dysmotility. Gastroenterology 2003; 125:70-9
15. Keime-Guibert F, Graus F, Fleury A, Rene R, Honnorat J, Broet P, et al. Treatment of paraneoplastic neurological syndromes with antineuronal antibodies (anti-Hu, Anti-Yo) with a combination of immunoglobins, cyclofosfamide, and methylprednisolone. J Neurol Neurosurg Psychiatry 2000; 68: 479-82
16. Keime-Guibert F, Graus F, Broet P, Rene R, Molinuevo JL, Ascaso C, et al. Clinical outcome of patients with anti-Hu associated encephalomyelitis after treatment of the tumor. Neurology 1999; 53: 1719-23