Intramural coronary artery constrictor reactivity to thromboxane is higher in male than in female rats

Gynecological Endocrinology

Volumn 22, Issue 1, 2006, Pages 44-47

  Varbiro, Szabolcs ^a   Matrai, Mate ^a   Szekeres, Maria ^a   Nadasy, Gyorgy L ^a   Szaky, Esther ^b   Mericli, Metin ^a   Banhidy, Ferenc ^a   Monos, Emil ^a   Szekacs, Bela ^a  

^a SEMMELWEIS UNIVERSITY   (Hungary)

^b York Central Hospital   (Canada)

Author keywords

Coronary artery; Females; Gender; Males; Rat; Thromboxane

Indexed keywords

RINGER SOLUTION; THROMBOXANE A2; THROMBOXANE A2 RECEPTOR STIMULATING AGENT; VASOCONSTRICTOR AGENT;

ANIMAL TISSUE; ARTERY DIAMETER; ARTICLE; BLOOD VESSEL INJURY; BLOOD VESSEL REACTIVITY; BLOOD VESSEL WALL; CARDIOVASCULAR RESPONSE; CONTROLLED STUDY; CORONARY ARTERY CONSTRICTION; FEMALE; LEFT ANTERIOR DESCENDING CORONARY ARTERY; MALE; NONHUMAN; PATHOLOGY; PRESSURE MEASUREMENT; PRIORITY JOURNAL; SEX DIFFERENCE; THROMBOCYTE RELEASE REACTION;

15-HYDROXY-11 ALPHA,9 ALPHA-(EPOXYMETHANO)PROSTA-5,13-DIENOIC ACID; ANIMALS; CORONARY VESSELS; FEMALE; MALE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, THROMBOXANE A2, PROSTAGLANDIN H2; SEX FACTORS; THROMBOXANE A2; VASOCONSTRICTION;

EID: 33644821319     PISSN: 09513590     EISSN: 14730766     Source Type: Journal    
DOI: 10.1080/09513590500453759     Document Type: Article

References (15)

1. Advance report of final mortality statistics, 1989. Mon Vital Stat Rep 1992;40:1-47.
2. British Heart Foundation/Coronary Prevention Group Statistics Database. Coronary heart disease statistics 1993. London: The British Heart Foundation; 1993.
3. Tanaka KA, Szlam F, Katori N, Tsuda A, Levy JH. In vitro effects of antihypertensive drugs on thromboxane agonist (U46619)-induced vasoconstriction in human internal mammary artery. Br J Anaesth 2004;93:257-262.
4. Nadasy GL, Szekacs B, Juhasz I, Feher J, Kovach AG, Monos E. Role of endothelium, oxygen and ionic milieu in the prostacyclin and thromboxane production of rat aortic tissue slices. Acta Physiol Hung 1991;78:77-87.
5. Szekacs B, Nadasy GL, Vajo Z, Juhasz I, Feher J, Monos E. Prostacyclin and thromboxane production of rat and cat arterial tissue is altered independently by several vasoactive substances. Prostaglandins 1996;52:221-235.
6. Luscher TF, Noll G. The pathogenesis of cardiovascular disease: role of endothelium as a target and mediator. Atherosclerosis 1995;118(Suppl):S81-S90.
7. 2 receptor antagonist S 18886 in patients with coronary artery disease treated with aspirin. J Am Coll Cardiol 2003;41:1198-1204.
8. Eikelboom LW, Hirsh J, Weitz JI, Johnston M, Yi Q, Yusuf S. Aspirin-resistant thromboxane biosynthesis and the risk of myocardial infarction, stroke, or cardiovascular death in patients at high risk for cardiovascular events. Circulation 2002;105:1650-1655.
9. Lamping KG, Nuno DW. Effects of 17-β estradiol on coronary microvascular responses to endothelin-1. Am J Physiol 1996;271:H1117-H1124.
10. Jiang C, Sarrel PM, Poole-Wilson PA, Collins P. Acute effect of 17β-estradiol on rabbit coronary artery contractile responses to endothelin-1. Am J Physiol 1992;263:H271-H275.
11. Karanian JW, Ramwell PW. Effect of gender and sex steroids on the contractile response of canine coronary and renal blood vessels. J Cardiovasc Pharmacol 1996;27:312-319.
12. Miller VM, Lewis DA, Barber DA. Gender differences and endothelium- and platelet-derived factors in the coronary circulation. Clin Exp Pharmacol Physiol 1999;26:132-136.
13. Szekeres M, Dezsi L, Nadasy GL, Kaley G, Koller A. Pharmacologic inhomogeneity between the reactivity of intramural coronary arteries and arterioles. J Cardiovasc Pharmacol 2001;38:584-592.
14. Nadasy GL, Szekeres M, Dezsi L, Varbiro S, Szekacs B, Monos E. Preparation of intramural small coronary artery and arteriole segments and resistance artery networks from the rat heart for microarteriography and for in situ perfusion video mapping. Microvasc Res 2001;61:282-286.
15. Mericli M, Nadasy GL, Szekeres M, Varbiro S, Vajo Z, Matrai M, Acs N, Monos E, Szekacs B. Estrogen replacement therapy reverses changes in intramural coronary resistance arteries caused by female sex hormone depletion. Cardiovasc Res 2004;61:317-324.