The expression of minichromosome maintenance protein-2 in normal and abnormal megakaryocytes and comparison with the proliferative marker Ki-67

British Journal of Haematology

Volumn 131, Issue 4, 2005, Pages 490-494

  Lampert, Irvin A ^a   Horncastle, Donna ^a   Dilworth, Steven ^b   Roberts, Irene ^a   Alison, Malcolm R ^c   Naresh, Kikkeri N ^a  

^a HAMMERSMITH HOSPITAL   (United Kingdom)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

^c QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

Cell quiescence; Endomitosis; Minichromosome maintenance 2; Platelet glycoprotein III (CD61); Polyploidy

Indexed keywords

KI 67 ANTIGEN; MINICHROMOSOME MAINTENANCE PROTEIN 2; BETA3 INTEGRIN; CELL CYCLE PROTEIN; ITGB3 PROTEIN, HUMAN; MCM2 PROTEIN, HUMAN; NUCLEAR PROTEIN;

ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; CYTOLOGY; ENDOREDUPLICATION; HUMAN; HUMAN CELL; MEGAKARYOCYTE; MITOSIS; MYELODYSPLASTIC SYNDROME; PRIORITY JOURNAL; PROTEIN EXPRESSION; BONE MARROW; CELL NUCLEUS; COMPARATIVE STUDY; CYTOPLASM; ERYTHROID PRECURSOR CELL; METABOLISM; MYELOPROLIFERATIVE DISORDER; PATHOLOGY;

BONE MARROW; CELL CYCLE PROTEINS; CELL NUCLEUS; CYTOPLASM; ERYTHROID PROGENITOR CELLS; HUMANS; INTEGRIN BETA3; KI-67 ANTIGEN; MEGAKARYOCYTES; MYELODYSPLASTIC SYNDROMES; MYELOPROLIFERATIVE DISORDERS; NUCLEAR PROTEINS;

EID: 33644815077     PISSN: 00071048     EISSN: 13652141     Source Type: Journal    
DOI: 10.1111/j.1365-2141.2005.05801.x     Document Type: Article

References (10)

1. Cip1/Waf1 in cell-cycle exit of endomitotic megakaryocytes. Blood, 98, 3274 3282.
2. Blow J.J. Laskey R.A. ( 1988) A role for the nuclear envelope in controlling DNA replication within the cell cycle. Nature, 332, 546 548.
3. Endl E. Kausch I. Baack M. Knippers R. Gerdes J. Scholzen T. ( 2001) The expression of Ki-67, MCM3, and p27 defines distinct subsets of proliferating, resting, and differentiated cells. Journal of Pathology, 195, 457 462.
4. Forsburg S.L. ( 2004) Eukaryotic MCM proteins: beyond replication initiation. Microbiology and Molecular Biology Reviews, 68, 109 131.
5. Freeman A. Morris L.S. Mills A.D. Stoeber K. Laskey R.A. Williams G.H. Coleman N. ( 1999) Minichromosome maintenance proteins as biological markers of dysplasia and malignancy. Clinical Cancer Research, 5, 2121 2132.
6. Jacobsson S. Carneskog J. Ridell B. Wadenvik H. Swolin B. Kutti J. ( 1996) Flow cytometric analysis of megakaryocyte ploidy in chronic myeloproliferative disorders and reactive thrombocytosis. European Journal of Haematology, 56, 287 292.
7. Kobayashi Y. Ozawa M. Maruo N. Kondo M. ( 1993) Megakaryocytic ploidy in myelodysplastic syndromes. Leukemia Lymphoma, 9, 55 61.
8. Lan H.Y. Wei M. Nikolic-Paterson D.J. Atkins R.C. ( 1995) A novel, simple, reliable and sensitive method for multiple immunoenzyme staining: use of microwave oven heating to block antibody crossreactivity and retrieve antigens. Journal of Histochemistry Cytochemistry, 43, 97 102.
9. Lei M. Tye B.K. ( 2001) Initiating DNA synthesis: from recruiting to activating the MCM complex. Journal of Cell Science, 114, 1447 1454.
10. Ravid K. Lu J. Zimmet J.M. Jones M.R. ( 2002) Roads to polyploidy: the megakaryocyte example. Journal of Cellular Physiology, 190, 7 20.