Neonatal nosocomial sepsis in a level-III NICU: Evaluation of the causative agents and antimicrobial susceptibilities

Turkish Journal of Pediatrics

Volumn 48, Issue 1, 2006, Pages 13-18

  Yalaz, Mehmet ^a   Çetin, Hasan ^a   Akisu, Mete ^a   Aydemir, Şöhret ^a   Tunger, Alper ^a   Kültürsay, Nilgün ^a  

^a EGE UNIVERSITY   (Turkey)

Author keywords

Etiology; Newborn; Sepsis; Treatment

Indexed keywords

AMIKACIN; AMINOGLYCOSIDE ANTIBIOTIC AGENT; AMPHOTERICIN B; CARBAPENEM; CEFTAZIDIME; CEPHALOSPORIN; FLUCONAZOLE; ISEPAMICIN; MEROPENEM; METICILLIN; NYSTATIN; PENICILLIN G; PIPERACILLIN; QUINOLONE; TAZOBACTAM; TEICOPLANIN;

ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ANTIBIOTIC THERAPY; ARTICLE; BACTERIUM ISOLATION; BLOOD CULTURE; CLINICAL FEATURE; COAGULASE NEGATIVE STAPHYLOCOCCUS; CONTROLLED STUDY; FEMALE; HOSPITAL INFECTION; HUMAN; INFANT; INFANT MORTALITY; KLEBSIELLA PNEUMONIAE; MAJOR CLINICAL STUDY; MALE; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MINIMUM INHIBITORY CONCENTRATION; MYCOSIS; NEWBORN INFECTION; NEWBORN INTENSIVE CARE; PSEUDOMONAS AERUGINOSA; RETROSPECTIVE STUDY; RISK ASSESSMENT; RISK FACTOR; SEPSIS; STAPHYLOCOCCUS AUREUS; STATISTICAL SIGNIFICANCE;

CROSS INFECTION; DRUG RESISTANCE, MICROBIAL; FEMALE; HUMANS; INFANT, NEWBORN; INFANT, PREMATURE; INFANT, PREMATURE, DISEASES; INTENSIVE CARE UNITS, NEONATAL; MALE; MICROBIAL SENSITIVITY TESTS; SEPSIS;

EID: 33644807959     PISSN: 00414301     EISSN: 00414301     Source Type: Journal    
DOI: None     Document Type: Article

References (18)

1. Smith J. Bacterial and fungal infections of the neonate. In: Pomerance JJ, Richardson CJ (eds). Neonatology for the Clinician (1st ed). Norwalk, Connecticut: Appleton and Lange; 1993: 185-193.
2. Siegel JD. Sepsis neonatorum. In: Oski FA, DeAngelis CD, Feigin RD,_Warshaw JB (eds). Principles and Practice of Pediatrics (1st ed). Philadelphia: JB Lippincott Co.; 1990: 471-479.
3. Freij BJ, McCracken GH. Acute infections. In: Avery GB, Fletcher MA, Mac Donald MG (eds). Neonatology: Pathophysiology and Management of the Newborn (4th ed) Philadelphia: JB Lippincott Co.; 1994: 1082-1094.
4. National Committee for Clinical Laboratory Standards. Analysis and presentation of cumulative antimicrobial susceptibility testing data; proposed guideline, M39-P. 1, National Committee for Clinical Laboratory Standards, Wayne, PA (2002).
5. Yalaz M, Hilmioglu S, Metin D, et al. Fatal disseminated Acremonium strictum infection in a preterm newborn: a very rare cause of neonatal septicemia. J Med Mic 2003; 52: 835-837.
6. Baltimore RS. Neonatal nosocomial infections. Semin Perinatol 1998; 22: 25-32.
7. Bradley JS. Management of neonates with suspected sepsis. Pediatr Infect Dis J 1991; 10: 343-345.
8. Moore DL. Nosocomial infection in newborn nurseries and neonatal intensive care units. In: Mayhall CG (ed). Hospital Epidemiology and Infection Control. Baltimore: Williams-Wilkins; 1996: 535-564.
9. Kilani RA, Basamad M. Pattern of proven bacterial sepsis in a neonatal intensive care unit in Riyadh-Saudi Arabia: a 2-year analysis. J Med Liban 2000; 48: 77-83.
10. Klein JO, Marcy SM. Bacterial sepsis and meningitis. In: Remington JS, Klein JO (eds). Infectious Diseases of the Fetus and Newborn Infant (3rd ed). Philadelphia: WB Saunders; 1990: 601-656.
11. Auriti C, Maccallini A, Di Liso G, Di Ciommo V, Ronchetti MP, Orzalesi M. Risk factors for nosocomial infections in a neonatal intensive-care unit. J Hosp Infect 2003; 53: 25-30.
12. Carrieri MP, Stolfi I, Moro ML. Italian Study Group on Hospital Acquired Infections in Neonatal Intensive Care Units. Intercenter variability and time of onset: two crucial issues in the analysis of risk factors for nosocomial sepsis. Pediatr Infect Dis J 2003; 22: 599-609.
13. Malik A, Hasani SE, Khan HM, Ahmad AJ. Nosocomial infections in newborns. Indian Pediatr 2001; 38: 68-71.
14. Karthikeyan G, Premkumar K. Neonatal sepsis: Staphylococcus aureus as the predominant pathogen. Indian J Pediatr 2001; 68: 715-717.
15. Anwer SK, Mustafa S, Pariyani S, Ashraf S, Taufiq KM. Neonatal sepsis: an etiological study. J Pak Med Assoc 2000; 50: 91-94.
16. Oral R, Akisu M, Kultursay N, Vardar F, Tansug N. Neonatal Klebsiella pneumonia sepsis and imipenem/cilastatin. Indian J Pediatr 1998; 65: 121-129.
17. Damjanovic V, Connolly CM, van Saene HK, et al. Selective decontamination with nystatin for control of a Candida outbreak in a neonatal intensive care unit. J Hosp Infect 1993; 24: 245-259.
18. Sims ME, Yoo Y, You H, Salminen C, Walther FJ. Prophylactic oral nystatin and fungal infections in very-low-birthweight infants. Am J Perinatol 1988; 5: 33-36.