Implications of microcirculation-research based information on prevention and treatment of diabetes mellitus type 2: A perspective

Clinical Hemorheology and Microcirculation

Volumn 34, Issue 1-2, 2006, Pages 43-50

  Bunnag, Srichitra C ^a  

^a CHULALONGKORN UNIVERSITY   (Thailand)

Author keywords

Ageing; Diabetes mellitus type 2 (T2DM); Hypertension; Reactive oxygen species (ROS)

Indexed keywords

ACETYLSALICYLIC ACID; ANTIOXIDANT; ANTITHROMBOCYTIC AGENT; ASCORBIC ACID; CLOPIDOGREL; CYTOTOXIC AGENT; DIPYRIDAMOLE; GARLIC EXTRACT; HYDROXYL RADICAL; MALONALDEHYDE; NITRIC OXIDE; OXIDIZING AGENT; PEROXYNITRITE; PHYTOSTEROL; REACTIVE OXYGEN METABOLITE; SUPEROXIDE;

AGING; ANTIOXIDANT ACTIVITY; ATHEROSCLEROSIS; CAPILLARY BLOOD; CARDIOVASCULAR RISK; CONFERENCE PAPER; DIET; ENDOTHELIAL DYSFUNCTION; EXERCISE; GLOMERULUS; HUMAN; HYPERGLYCEMIA; HYPERTENSION; HYPERTRIGLYCERIDEMIA; IMPAIRED GLUCOSE TOLERANCE; INSULIN RESISTANCE; LEUKOCYTE ADHERENCE; LIFESTYLE; MEDICAL RESEARCH; METABOLIC SYNDROME X; MICROCIRCULATION; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OBESITY; OXIDATIVE STRESS; PANCREAS ISLET; RISK FACTOR; VASCULARIZATION; VASODILATATION;

DIABETES MELLITUS, TYPE 2; ENDOTHELIUM, VASCULAR; HUMANS; HYPERTENSION; MICROCIRCULATION; REACTIVE OXYGEN SPECIES; RISK FACTORS;

EID: 33644807264     PISSN: 13860291     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (35)

1. International Diabetes Federation, New diabetes figures, Press release, 25 August 2003, Available at: www.idf.org/home/ index.cfm, accessed 23 February, 2004.
2. American Diabetes Association. Standards of medical care in diabetes, Diabetes Care, 27(Suppl.) (2004), 515-535.
3. A.R. Shuldiner and J.C. McLenithan, Genes and pathophysiology of type 2 diabetes: more than just the Randle cycle all over again, J. Clin. Invest. 114 (2004), 1414-1417.
4. C. Ling, P. Poulsen, E. Carisson, M. Ridderstrale, P. Almgren, J. Wojtasewski, H. Beck-Nielsen, L. Groop and A. Vaag, Multiple environmental and genetic factors influence skeletal muscle PGC-1α and PGC-1β gene expression in twins, J. Clin. Invest. 114 (2004), 1518-1526.
5. M. Ushio-Fukai, R.W. Alexander, M. Akers and K.K. Griendling, Mitogen-activated protein kinase is a critical component of the redox-sensitive signaling pathways activated by angiotensin II. Role in vascular smooth muscle cell hypertrophy, J. Biol. Chem. 273 (1998), 15022-15029.
6. D.A. Cohen and C.G. Schalkwijk, Endothelial function and dysfunction, in: International Textbook of Diabetes Mellitus, H. Keen and P. Zimmet, eds, Vol. II, 3rd edn. John Wiley & Sons, England, 2004, pp. 1409-1423.
7. H.G. Bohlen and J.M. Lash, Topical hyperglycemia rapidly suppresses EDRF-mediated vasodilation of normal rat arterioles, Am. J. Physiol. 265 (1993), 219-225.
8. B. Tesfamarian, B.M.L. Brown, D. Deykin and R.A. Cohen, Elevated glucose promotes generation of endothelium-derived vasoconstrictor prostanoids in rabbit aorta, J. Clin. Invest. 85 (1990), 929-932.
9. G.M. Pieper and G. Gross, Oxygen-derived free radicals abolish endothelium-dependent relaxation in diabetic rat aorta, Am. J. Physiol. 225 (1988), 825-833.
10. W. Durante, A.K. Sen and F.A. Sunahara, Impairment of endothelium-dependent relaxation in aortae from spontaneously diabetic rats, Br. J. Pharmacol. 94 (1988), 463-468.
11. J.M. Lash and H.G. Bohlen, Structural and functional origins of suppressed acetylcholine vasodilation in diabetic rat intestinal arterioles, Circ. Res. 69 (1991), 1259-1268.
12. Y. Oyama, H. Kawasaki, Y. Hattori and M. Kanno, Attenuation of endothelium-dependent relaxation in aorta from diabetic rats, Eur. J. Pharmacol. 131 (1986), 75-78.
13. A. Jariyapongsakul, S. Patumraj and H. Niimi, Cerebral endothelial dysfunction in diabetes: intravital microscopic analysis using streptozotocin-induced diabetic rats, Clin. Hemorheol. Microcirc. 29 (2003), 331-335.
14. D. Chakraphan, P. Sridulyakul, B. Thipakorn, S. Bunnag, V.H. Huxley and S. Patumraj, Attenuation of endothelial dysfunction by exercise training in STZ-induced diabetic rats, Clin. Hemorheol. Microcirc. 32 (2005), 217-226.
15. A. Jaripongsakul, S. Patumraj, S. Yamaguchi and H. Niimi, The effect of long-term supplementation of vitamin C on leukocyte adhesion to the cerebral endothelium in STZ-induced diabetic rats, Clin. Hemorheol. Microcirc. 27 (2002), 67-76.
16. H.H. Ting, F.K. Timimi, K.S. Boles, S.J. Creager, P. Gang and M.A. Creager, Vitamin C improves endothelium-dependent vasodilation in patients with non-insulin-dependent diabatea mellitus, J. Clin. Invest. 97 (1996), 22-28.
17. R.J. Geyglewski, R.M.J. Plamer and S. Moncada, Superoxide anion is involved in the breakdown of endothelium-derived vascular relaxing factor, Nature (Lond.) 320 (1986), 454-456.
18. A. Mugge, J.H. Elwell, T.E. Peterson and D.E. Harrison, Release of intact endothelium-derived relaxing factor depends on endothelial superoxide dismutase activity, Am. J. Physiol. 260 (1991), 219-225.
19. G.M. Rubanyi and P.M. Vanhoutte, Oxygen-derived free radicals, endothelium and responsiveness of vascular smooth muscle, Am. J. Physiol. 250 (1986), 815-821.
20. J.S. Beckman, T.W. Beckman, J. Chen, P.A. Marshall and B.A. Freeman, Apparent hydroxyl radical production by peroxynitrite, Proc. Natl. Acad. Sci. USA 87 (1990), 1620-1624.
21. B. Tesfamarium and R.A. Cohen, Free radicals mediate endothelial cell dysfunction caused by elevated glucose, Am. J. Physiol. 263 (1992), 321-326.
22. S.C. Bunnag, S. Bunnag and N.E. Warner, Microscopy of the living pancereas in situ, Am. J. Anat. 126 (1963), 395-408.
23. S.C. Bunnag, Postnatal neogenesis of islets of Langehans in the mouse, Diabetes 15 (1966), 480-491.
24. S.C. Bunnag, Microcirculation, endothelial cell injury and pathogenesis of non-insulin dependent diabetes mellitus (NIDDM), in: The Third Asian Congress for Microcirculation, S.C. Bunnag, A. Srikiatkhachorn and S. Patumraj, eds, Monduzzi, Bologna, Italy, 1998, pp. 27-32.
25. S.C. Bunnag, K. Banchuin and C. Sitthi-Amorn, Prevalence and risk factors of hypertension in elderly Thais, Gerontology: East/West Cooperation, in: Proc. the 3rd Regional Congress, Bolga Press, Curtin, Australia, 1987, pp. 72-74.
26. S.C. Bunnag, K. Banchuin and C. Sitthi-Amorn, Prevalence and risk factors of diabetes in the elderly Thais, in: Program & Abstracts of Asia/Oceania Region 3rd Regional Congress. Inter. Assoc. Gerontol., Bangkok, 23-26 Nov., 1987, p. 39.
27. C. Sitthi-Amorn, S. Chandraprasert, S.C. Bunnag and C.S. Plengvidhya, The prevalence and risk factors of hypertension in Klong Toey Slum and Klong Toey Government House, Int. J. Epidemiol. 18 (1989), 89-94.
28. S.C. Bunnag, C. Sitthi-Amom and S. Chandraprasert, The prevalence of obesity, risk factors and associated diseases in Klong Toey Slum and Klong Toey Government Apartment Houses, Diabetes Res. Clin. Practice 10 (1990), 81-87.
29. S.C. Bunnag, S. Serirat, S. Pongsabutr, S. Sitprija, S. Chandraprasert and P. Savetrun, Prevalence and clinical pattern of diabetes mellitus in Thailand, J. ASEAN Fed. Endocr. Soc. 1 (1982), 129-140.
30. A. Ceriello, C. Taboga, L. Tonutti, L. Quagliaro, L. Piconi, B. Bais, R. DaRos and E. Motz, Evidence for an independent and cumulative effect of postprandial hypertriglyceridemia and hyperglycemia on endothelial dysfunction and oxidative stress generation, Circulation 106 (2002), 1211-1218.
31. L. Fontana, T.E. Meyer, S. Klein and J.O. Hollaszy, Long-term calorie restriction is highly effective in reducing the risk for atherosclerosis in humans, Proc. Natl. Acad. Sci. USA 101 (2004), 6659-6663.
32. C.C. Hsu, M.C. Yin and R. Tian, Ascorbic acid and uric acid suppress glucose-induced fibronectim and vascular endothelial growth factor production in human endothelial cells, J. Diab. Compl. 19 (2005), 96-100.
33. D.K. Yue, S. McLennan, M. McGill, L. Fisher, S. Hefferman, C. Capogreco and J.R. Turtle, Abnormalities of ascorbic acid metabolisum and diabetic control between diabetic patients and diabetic rats, Diab. Res. Clin. Practice 9 (1990), 239-244.
34. S. Patumraj, V. Kasantikul, S. Tewit and P. Sermpakdeekul, The study of garlic extract on diabetic cardiovascular complications, Microcirculation Annual 13 (1997), 31-34.
35. S. Patumraj, S. Tewit, S. Amatyakul, A. Jariyapongsakul, S. Maneesri, V. Kasantikul and D. Shepro, Comparative effects of garlic and aspirin on diabetic cardiovascular complication, Drug Delivery 7 (2000), 1-6.