-
1
-
-
0344927562
-
Conjugate export pumps of the multidrug resistance protein (MRP) family: Localization, substrate specificity, and MRP2-mediated drug resistance
-
J. Konig, A.T. Nies, Y. Cui, I. Leier, and D. Keppler Conjugate export pumps of the multidrug resistance protein (MRP) family: localization, substrate specificity, and MRP2-mediated drug resistance Biochim. Biophys. Acta 1461 1999 377 394
-
(1999)
Biochim. Biophys. Acta
, vol.1461
, pp. 377-394
-
-
Konig, J.1
Nies, A.T.2
Cui, Y.3
Leier, I.4
Keppler, D.5
-
2
-
-
0036364467
-
Multidrug resistance in cancer: Role of ATP-dependent transporters
-
M.M. Gottesman, T. Fojo, and S.E. Bates Multidrug resistance in cancer: role of ATP-dependent transporters Nat. Rev. Cancer 2 2002 48 58
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 48-58
-
-
Gottesman, M.M.1
Fojo, T.2
Bates, S.E.3
-
3
-
-
0034674901
-
A family of drug transporters: The multidrug resistance-associated proteins
-
P. Borst, R. Evers, M. Kool, and J. Wijnholds A family of drug transporters: the multidrug resistance-associated proteins J. Natl Cancer Inst. 92 2000 1295 1302
-
(2000)
J. Natl Cancer Inst.
, vol.92
, pp. 1295-1302
-
-
Borst, P.1
Evers, R.2
Kool, M.3
Wijnholds, J.4
-
6
-
-
0034674901
-
A family of drug transporters: The multidrug resistance-associated proteins
-
P. Borst, R. Evers, M. Kool, and J. Wijnholds A family of drug transporters: the multidrug resistance-associated proteins J. Natl Cancer Inst. 92 2000 1295 1302
-
(2000)
J. Natl Cancer Inst.
, vol.92
, pp. 1295-1302
-
-
Borst, P.1
Evers, R.2
Kool, M.3
Wijnholds, J.4
-
7
-
-
0033764825
-
The human multidrug resistance-associated protein (MRP) gene family: From biological function to drug molecular design
-
T. Ishikawa, M.T. Kuo, K. Furuta, and M. Suzuki The human multidrug resistance-associated protein (MRP) gene family: from biological function to drug molecular design Clin. Chem. Lab. Med. 38 2000 893 897
-
(2000)
Clin. Chem. Lab. Med.
, vol.38
, pp. 893-897
-
-
Ishikawa, T.1
Kuo, M.T.2
Furuta, K.3
Suzuki, M.4
-
8
-
-
85163548581
-
MRP2, the apical export pump for anionic conjugates
-
C.F. Higgins Academic Press Amsterdam
-
J. König, A.T. Nies, Y. Cui, D. Keppler, I.B. Holland, and S.P.C. Cole MRP2, the apical export pump for anionic conjugates C.F. Higgins ABC Proteins: from Bacteria to Man 2003 Academic Press Amsterdam 423 443
-
(2003)
ABC Proteins: From Bacteria to Man
, pp. 423-443
-
-
König, J.1
Nies, A.T.2
Cui, Y.3
Keppler, D.4
Holland, I.B.5
Cole, S.P.C.6
-
9
-
-
9544233652
-
A human canalicular multispecific organic anion transporter (cMOAT) gene is overexpressed in cisplatin-resistant human cancer cell lines with decreased drug accumulation
-
K. Taniguchi, M. Wada, K. Kohno, T. Nakamura, T. Kawabe, and M. Kawakami A human canalicular multispecific organic anion transporter (cMOAT) gene is overexpressed in cisplatin-resistant human cancer cell lines with decreased drug accumulation Cancer Res. 56 1996 4124 4129
-
(1996)
Cancer Res.
, vol.56
, pp. 4124-4129
-
-
Taniguchi, K.1
Wada, M.2
Kohno, K.3
Nakamura, T.4
Kawabe, T.5
Kawakami, M.6
-
10
-
-
0040761368
-
CDNA cloning of the hepatocyte canalicular isoform of the multidrug resistance protein, cMrp, reveals a novel conjugate export pump deficient in hyperbilirubinemic mutant rats
-
M. Buchler, J. Konig, M. Brom, J. Kartenbeck, H. Spring, and T. Horie cDNA cloning of the hepatocyte canalicular isoform of the multidrug resistance protein, cMrp, reveals a novel conjugate export pump deficient in hyperbilirubinemic mutant rats J. Biol. Chem. 271 1996 15091 15098
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 15091-15098
-
-
Buchler, M.1
Konig, J.2
Brom, M.3
Kartenbeck, J.4
Spring, H.5
Horie, T.6
-
11
-
-
0031031247
-
Molecular cloning of canalicular multispecific organic anion transporter defective in EHBR rats
-
K. Ito, H. Suzuki, T. Hirohashi, K. Kume, T. Shimizu, and Y. Sugiyama Molecular cloning of canalicular multispecific organic anion transporter defective in EHBR rats Am. J. Physiol. 35 1997 G16 G22
-
(1997)
Am. J. Physiol.
, vol.35
-
-
Ito, K.1
Suzuki, H.2
Hirohashi, T.3
Kume, K.4
Shimizu, T.5
Sugiyama, Y.6
-
12
-
-
0029981430
-
Congenital jaundice in rats with a mutation in a multidrug resistanceassociated protein gene
-
C.C. Paulusma, P.J. Bosma, G.J. Zaman, C.T. Bakker, M. Otter, and G.L. Scheffer Congenital jaundice in rats with a mutation in a multidrug resistanceassociated protein gene Science 271 1996 1126 1128
-
(1996)
Science
, vol.271
, pp. 1126-1128
-
-
Paulusma, C.C.1
Bosma, P.J.2
Zaman, G.J.3
Bakker, C.T.4
Otter, M.5
Scheffer, G.L.6
-
13
-
-
0032577901
-
Doxorubicin- and daunorubicin-glutathione conjugates, but not unconjugated drugs, competitively inhibit leukotriene C4 transport mediated by MRP/GS-X pump
-
W. Priebe, M. Krawczyk, M.T. Kuo, Y. Yamane, N. Savaraj, and T. Ishikawa Doxorubicin- and daunorubicin-glutathione conjugates, but not unconjugated drugs, competitively inhibit leukotriene C4 transport mediated by MRP/GS-X pump Biochem. Biophys. Res. Commun. 247 1998 859 863
-
(1998)
Biochem. Biophys. Res. Commun.
, vol.247
, pp. 859-863
-
-
Priebe, W.1
Krawczyk, M.2
Kuo, M.T.3
Yamane, Y.4
Savaraj, N.5
Ishikawa, T.6
-
14
-
-
0032534064
-
Characterization of vincristine transport by the M(r) 190,000 multidrug resistance protein (MRP): Evidence for cotransport with reduced glutathione
-
D.W. Loe, R.G. Deeley, and S.P. Cole Characterization of vincristine transport by the M(r) 190,000 multidrug resistance protein (MRP): evidence for cotransport with reduced glutathione Cancer Res. 58 1998 5130 5136
-
(1998)
Cancer Res.
, vol.58
, pp. 5130-5136
-
-
Loe, D.W.1
Deeley, R.G.2
Cole, S.P.3
-
15
-
-
0030063480
-
Transport of glutathione, glucuronate, and sulfate conjugates by the MRP gene-encoded conjugate export pump
-
G. Jedlitschky, I. Leier, U. Buchholz, K. Barnouin, G. Kurz, and D. Keppler Transport of glutathione, glucuronate, and sulfate conjugates by the MRP gene-encoded conjugate export pump Cancer Res. 56 1996 988 994
-
(1996)
Cancer Res.
, vol.56
, pp. 988-994
-
-
Jedlitschky, G.1
Leier, I.2
Buchholz, U.3
Barnouin, K.4
Kurz, G.5
Keppler, D.6
-
16
-
-
0026459859
-
The ATP-dependent glutathione S-conjugate export pump
-
T. Ishikawa The ATP-dependent glutathione S-conjugate export pump Trends Biochem. Sci. 17 1992 463 468
-
(1992)
Trends Biochem. Sci.
, vol.17
, pp. 463-468
-
-
Ishikawa, T.1
-
17
-
-
0034072174
-
Interactions of the human multidrug resistance proteins MRP1 and MRP2 with organic anions
-
E. Bakos, R. Evers, J.A. Sinkule, A. Varadi, P. Borst, and B. Sarkadi Interactions of the human multidrug resistance proteins MRP1 and MRP2 with organic anions Mol. Pharmacol. 57 2000 760 768
-
(2000)
Mol. Pharmacol.
, vol.57
, pp. 760-768
-
-
Bakos, E.1
Evers, R.2
Sinkule, J.A.3
Varadi, A.4
Borst, P.5
Sarkadi, B.6
-
18
-
-
0030009305
-
Multidrug resistance protein (MRP)-mediated transport of leukotriene C4 and chemotherapeutic agents in membrane vesicles: Demonstration of glutathione-dependent vincristine transport
-
D.W. Loe, K.C. Almquist, R.G. Deeley, and S.P.C. Cole Multidrug resistance protein (MRP)-mediated transport of leukotriene C4 and chemotherapeutic agents in membrane vesicles: demonstration of glutathione-dependent vincristine transport J. Biol. Chem. 271 1996 9675 9682
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 9675-9682
-
-
Loe, D.W.1
Almquist, K.C.2
Deeley, R.G.3
Cole, S.P.C.4
-
19
-
-
0029918142
-
ATP-dependent 17-estradiol 17-(-D-glucuronide) transport by multidrug resistance protein: Inhibition by cholestatic steroids
-
D.W. Loe, K.C. Almquist, S.P.C. Cole, and R.G. Deeley ATP-dependent 17-estradiol 17-(-D-glucuronide) transport by multidrug resistance protein: inhibition by cholestatic steroids J. Biol. Chem. 271 1996 9683 9689
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 9683-9689
-
-
Loe, D.W.1
Almquist, K.C.2
Cole, S.P.C.3
Deeley, R.G.4
-
20
-
-
0030962253
-
ATP-dependent transport of aflatoxin B1 and its glutathione conjugates by the product of the MRP gene
-
D.W. Loe, R.K. Stewart, T.E. Massey, R.G. Deeley, and S.P.C. Cole ATP-dependent transport of aflatoxin B1 and its glutathione conjugates by the product of the MRP gene Mol. Pharmacol. 51 1997 1034 1041
-
(1997)
Mol. Pharmacol.
, vol.51
, pp. 1034-1041
-
-
Loe, D.W.1
Stewart, R.K.2
Massey, T.E.3
Deeley, R.G.4
Cole, S.P.C.5
-
21
-
-
0025132673
-
ATP-dependent primary active transport of cysteinyl leukotrienes across liver canalicular membrane. Role of the ATP-dependent transport system for glutathione S-conjugates
-
T. Ishikawa, M. Müller, C. Klünemann, U. Berger, L. Lucka, and A. Schreyer ATP-dependent primary active transport of cysteinyl leukotrienes across liver canalicular membrane. Role of the ATP-dependent transport system for glutathione S-conjugates J. Biol. Chem. 265 1990 19279 19286
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 19279-19286
-
-
Ishikawa, T.1
Müller, M.2
Klünemann, C.3
Berger, U.4
Lucka, L.5
Schreyer, A.6
-
22
-
-
0031449603
-
Transport of glutathione prostaglandin a conjugates by the multidrug resistance protein 1
-
R. Evers, N.H. Cnubben, J. Wijnholds, L. Van Deemter, P.J. Van Bladeren, and P. Borst Transport of glutathione prostaglandin a conjugates by the multidrug resistance protein 1 Fed. Eur. Biochem. Soc. Lett. 419 1997 112 116
-
(1997)
Fed. Eur. Biochem. Soc. Lett.
, vol.419
, pp. 112-116
-
-
Evers, R.1
Cnubben, N.H.2
Wijnholds, J.3
Van Deemter, L.4
Van Bladeren, P.J.5
Borst, P.6
-
23
-
-
0031009385
-
Anthracyclines modulate multidrug resistance protein (MRP) mediated organic anion transport
-
M. Heijn, J.H. Hooijberg, G.L. Scheffer, G. Szabo, H.V. Westerhoff, and J. Lankelma Anthracyclines modulate multidrug resistance protein (MRP) mediated organic anion transport Biochim. Biophys. Acta 1326 1997 12 22
-
(1997)
Biochim. Biophys. Acta
, vol.1326
, pp. 12-22
-
-
Heijn, M.1
Hooijberg, J.H.2
Scheffer, G.L.3
Szabo, G.4
Westerhoff, H.V.5
Lankelma, J.6
-
24
-
-
0030878058
-
Modulation by (iso)flavonoids of the ATPase activity of the multidrug resistance protein
-
J.H. Hooijberg, H.J. Broxterman, M. Heijn, D.L. Fles, J. Lankelma, and H.M. Pinedo Modulation by (iso)flavonoids of the ATPase activity of the multidrug resistance protein Fed. Eur. Biochem. Soc. Lett. 413 1997 344 348
-
(1997)
Fed. Eur. Biochem. Soc. Lett.
, vol.413
, pp. 344-348
-
-
Hooijberg, J.H.1
Broxterman, H.J.2
Heijn, M.3
Fles, D.L.4
Lankelma, J.5
Pinedo, H.M.6
-
25
-
-
0030668526
-
ATP-dependent transport of bilirubin glucuronides by the multidrug resistance protein MRP1 and its hepatocyte canalicular isoform MRP2
-
G. Jedlitschky, I. Leier, U. Buchholz, J. Hummel-Eisenbeiss, B. Burchell, and D. Keppler ATP-dependent transport of bilirubin glucuronides by the multidrug resistance protein MRP1 and its hepatocyte canalicular isoform MRP2 Biochem. J. 327 1997 305 310
-
(1997)
Biochem. J.
, vol.327
, pp. 305-310
-
-
Jedlitschky, G.1
Leier, I.2
Buchholz, U.3
Hummel-Eisenbeiss, J.4
Burchell, B.5
Keppler, D.6
-
26
-
-
0035958862
-
Transport of the β-O-glucuronide conjugate of the tobacco-specific carcinogen 4- (methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) by the multidrug resistance protein 1 (MRP1), requirement for glutathione or a non-sulfur-containing analog
-
E.M. Leslie, K.-I. Ito, P. Upadhyaya, S.S. Hecht, R.G. Deeley, and S.P.C. Cole Transport of the β-O-glucuronide conjugate of the tobacco-specific carcinogen 4- (methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) by the multidrug resistance protein 1 (MRP1), requirement for glutathione or a non-sulfur-containing analog J. Biol. Chem. 276 2001 27846 27854
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 27846-27854
-
-
Leslie, E.M.1
Ito, K.-I.2
Upadhyaya, P.3
Hecht, S.S.4
Deeley, R.G.5
Cole, S.P.C.6
-
27
-
-
0001308329
-
Drug export activity of the human canalicular multispecific organic anion transporter in polarized kidney MDCK cells expressing cMOAT (MRP2) cDNA
-
R. Evers, M. Kool, L. Van, H. Jansen, J. Calafat, and L.C. Oomen Drug export activity of the human canalicular multispecific organic anion transporter in polarized kidney MDCK cells expressing cMOAT (MRP2) cDNA J. Clin. Invest. 101 1998 1310 1319
-
(1998)
J. Clin. Invest.
, vol.101
, pp. 1310-1319
-
-
Evers, R.1
Kool, M.2
Van, L.3
Jansen, H.4
Calafat, J.5
Oomen, L.C.6
-
28
-
-
0035034532
-
Increased bioavailability of the food-derived carcinogen 2-amino-1-methyl-6-phenylimidazo [4,5-b] pyridine in MRP2-deficient rats
-
C.G. Dietrich, D.R. De Waart, R. Ottenhoff, I.G. Schoots, and R.P. Elferink Increased bioavailability of the food-derived carcinogen 2-amino-1-methyl-6-phenylimidazo [4,5-b] pyridine in MRP2-deficient rats Mol. Pharmacol. 59 2001 974 980
-
(2001)
Mol. Pharmacol.
, vol.59
, pp. 974-980
-
-
Dietrich, C.G.1
De Waart, D.R.2
Ottenhoff, R.3
Schoots, I.G.4
Elferink, R.P.5
-
29
-
-
0030814774
-
The canalicular multispecific organic anion transporter and conjugated hyperbilirubinemia in rat and man
-
C.C. Paulusma, and R. Oude Elferink The canalicular multispecific organic anion transporter and conjugated hyperbilirubinemia in rat and man J. Mol. Med. 75 1997 420 428
-
(1997)
J. Mol. Med.
, vol.75
, pp. 420-428
-
-
Paulusma, C.C.1
Oude Elferink, R.2
-
30
-
-
0034721764
-
The MRP2/cMOAT transporter and arsenic-glutathione complex formation are required for biliary excretion of arsenic
-
S.V. Kala, M.W. Neely, G. Kala, C.I. Prater, D.W. Atwood, and J.S. Rice The MRP2/cMOAT transporter and arsenic-glutathione complex formation are required for biliary excretion of arsenic J. Biol. Chem. 275 2000 33404 33408
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 33404-33408
-
-
Kala, S.V.1
Neely, M.W.2
Kala, G.3
Prater, C.I.4
Atwood, D.W.5
Rice, J.S.6
-
31
-
-
0019278267
-
Hepatocellular carcinoma in a case of Dubin-Johnson syndrome treated successfully with right extended lobectomy
-
J. Okamura, M. Monden, S. Horikawa, O. Sikujara, G. Kosaki, and K. Seki Hepatocellular carcinoma in a case of Dubin-Johnson syndrome treated successfully with right extended lobectomy Jpn. J. Surg. 10 1980 343 347
-
(1980)
Jpn. J. Surg.
, vol.10
, pp. 343-347
-
-
Okamura, J.1
Monden, M.2
Horikawa, S.3
Sikujara, O.4
Kosaki, G.5
Seki, K.6
-
32
-
-
0019941552
-
A black hepatocellular carcinoma with Dubin-Johnson-like pigment and mallory bodies: A histochemical and ultrastructural study
-
J.A. Roth, E. Berman, D. Befeler, and F.B. Johnson A black hepatocellular carcinoma with Dubin-Johnson-like pigment and mallory bodies: a histochemical and ultrastructural study Am. J. Surg. Pathol. 6 1982 375 382
-
(1982)
Am. J. Surg. Pathol.
, vol.6
, pp. 375-382
-
-
Roth, J.A.1
Berman, E.2
Befeler, D.3
Johnson, F.B.4
-
33
-
-
0023407554
-
Dubin-Johnson syndrome associated with hepatocellular carcinoma - Report of an autopsy case
-
A. Sakamoto, I. Mori, K. Kawai, and H. Tsuchiyama Dubin-Johnson syndrome associated with hepatocellular carcinoma - report of an autopsy case Gan No Rinsho (Jpn. J. Cancer Clin.) 33 1987 1361 1367
-
(1987)
Gan No Rinsho (Jpn. J. Cancer Clin.)
, vol.33
, pp. 1361-1367
-
-
Sakamoto, A.1
Mori, I.2
Kawai, K.3
Tsuchiyama, H.4
-
34
-
-
0033712640
-
Multiple black hepatocellular adenomas in a male patient
-
P.H. Bernard, J.F. Blanc, C. Paulusma, B. Le, J. Carles, and C. Balabaud Multiple black hepatocellular adenomas in a male patient Eur. J. Gastroenterol. Hepatol. 12 2000 1253 1257
-
(2000)
Eur. J. Gastroenterol. Hepatol.
, vol.12
, pp. 1253-1257
-
-
Bernard, P.H.1
Blanc, J.F.2
Paulusma, C.3
Le, B.4
Carles, J.5
Balabaud, C.6
-
35
-
-
0026947534
-
Japanese clinical statistical data of patients with constitutional jaundice
-
Y. Adachi, T. Nanno, and T. Yamamoto Japanese clinical statistical data of patients with constitutional jaundice Nippon Rinsho (Jpn. J. Clin. Med.) 50 1992 677 685 (in Japanese)
-
(1992)
Nippon Rinsho (Jpn. J. Clin. Med.)
, vol.50
, pp. 677-685
-
-
Adachi, Y.1
Nanno, T.2
Yamamoto, T.3
-
36
-
-
0032429384
-
Postoperative management following massive hepatectomy in a patient with Dubin-Johnson syndrome: Report of a case
-
S. Ueno, G. Tanabe, K. Hanazono, H. Ogawa, S. Yoshidome, and T. Aikou Postoperative management following massive hepatectomy in a patient with Dubin-Johnson syndrome: report of a case Surg. Today 28 1998 1274 1278
-
(1998)
Surg. Today
, vol.28
, pp. 1274-1278
-
-
Ueno, S.1
Tanabe, G.2
Hanazono, K.3
Ogawa, H.4
Yoshidome, S.5
Aikou, T.6
-
37
-
-
0017695106
-
Clinical study of the constitutional hyperbilirubinemia in Japan. a nationwide survey between 1970 and 1974
-
T. Takino, T. Takahashi, and T. Okuno Clinical study of the constitutional hyperbilirubinemia in Japan. A nationwide survey between 1970 and 1974 Jpn. J. Gastroenterol. 74 1977 1518 1528
-
(1977)
Jpn. J. Gastroenterol.
, vol.74
, pp. 1518-1528
-
-
Takino, T.1
Takahashi, T.2
Okuno, T.3
-
38
-
-
0033361943
-
Genomic structure of the canalicular multispecific organic anion-transporter gene (MRP2/cMOAT) and mutations in the ATPBinding-cassette region in Dubin-Johnson syndrome
-
S. Toh, M. Wada, T. Uchiumi, A. Inokuchi, Y. Makino, and Y. Horie Genomic structure of the canalicular multispecific organic anion-transporter gene (MRP2/cMOAT) and mutations in the ATPBinding-cassette region in Dubin-Johnson syndrome Am. J. Hum. Genet. 64 1999 739 746
-
(1999)
Am. J. Hum. Genet.
, vol.64
, pp. 739-746
-
-
Toh, S.1
Wada, M.2
Uchiumi, T.3
Inokuchi, A.4
Makino, Y.5
Horie, Y.6
-
39
-
-
0041668155
-
The role of pglycoprotein in intestinal tumorigenesis: Disruption of indula suppresses polyp formation in ApcMin,4 mice
-
Y. Mochida, K. Taguchi, S. Taniguchi, M. Tsuneyoshi, H. Kuwano, and T. Tsuzuki The role of pglycoprotein in intestinal tumorigenesis: disruption of indula suppresses polyp formation in ApcMin,4 mice Carcinogenesis 24 2003 1219 1224
-
(2003)
Carcinogenesis
, vol.24
, pp. 1219-1224
-
-
Mochida, Y.1
Taguchi, K.2
Taniguchi, S.3
Tsuneyoshi, M.4
Kuwano, H.5
Tsuzuki, T.6
-
40
-
-
0037373889
-
Suppression of intestinal polyposis in Mdrl-deficient ApcMin/_ mice
-
T. Yamada, Y. Mari, R. Hayashi, M. Takada, Y. Ino, and Y. Naishiao Suppression of intestinal polyposis in Mdrl-deficient ApcMin/_ mice Cancer Res. 63 2003 895 901
-
(2003)
Cancer Res.
, vol.63
, pp. 895-901
-
-
Yamada, T.1
Mari, Y.2
Hayashi, R.3
Takada, M.4
Ino, Y.5
Naishiao, Y.6
-
41
-
-
0025325922
-
Carvalho: Diagnostic and pathogenetic implications of urinary coproporphyrin excretion in the Dubin-Johnson syndrome
-
M. Frank, M. Doss, and D.G. De Carvalho Carvalho: diagnostic and pathogenetic implications of urinary coproporphyrin excretion in the Dubin-Johnson syndrome Hepatogastroenterology 37 1990 147 151
-
(1990)
Hepatogastroenterology
, vol.37
, pp. 147-151
-
-
Frank, M.1
Doss, M.2
De Carvalho, D.G.3
-
42
-
-
0035103009
-
Polymorphism of the ABC transporter genes, MDR1, MRP1 and MRP2/cMOAT, in healthy Japanese subjects
-
S. Ito, I. Ieiri, M. Tanabe, A. Suzuki, S. Higuchi, and K. Otsubo Polymorphism of the ABC transporter genes, MDR1, MRP1 and MRP2/cMOAT, in healthy Japanese subjects Pharmacogenetics 11 2001 175 184
-
(2001)
Pharmacogenetics
, vol.11
, pp. 175-184
-
-
Ito, S.1
Ieiri, I.2
Tanabe, M.3
Suzuki, A.4
Higuchi, S.5
Otsubo, K.6
-
43
-
-
0036246271
-
Identification of 779 genetic variations in eight genes encoding members of the ATP-binding cassette, subfamily C (ABCC/MRP/CFTR)
-
S. Saito, A. Iida, A. Sekine, C. Ogawa, S. Kawauchi, and S. Higuchi Identification of 779 genetic variations in eight genes encoding members of the ATP-binding cassette, subfamily C (ABCC/MRP/CFTR) J. Hum. Genet. 47 2002 147 171
-
(2002)
J. Hum. Genet.
, vol.47
, pp. 147-171
-
-
Saito, S.1
Iida, A.2
Sekine, A.3
Ogawa, C.4
Kawauchi, S.5
Higuchi, S.6
-
44
-
-
0037131880
-
Single nucleotide polymorphisms in multidrug resistance associated protein 2 (MRP2/ABCC2): Its impact on drug disposition
-
H. Suzuki, and Y. Sugiyama Single nucleotide polymorphisms in multidrug resistance associated protein 2 (MRP2/ABCC2): its impact on drug disposition Adv. Drug Deliv. Rev. 54 2002 1311 1331
-
(2002)
Adv. Drug Deliv. Rev.
, vol.54
, pp. 1311-1331
-
-
Suzuki, H.1
Sugiyama, Y.2
-
45
-
-
0029986408
-
Absence of the canalicular isoform of the MRP gene-encoded conjugate export pump from the hepatocytes in Dubin-Johnson syndrome
-
J. Kartenbeck, U. Leuschner, R. Mayer, and D. Keppler Absence of the canalicular isoform of the MRP gene-encoded conjugate export pump from the hepatocytes in Dubin-Johnson syndrome Hepatology 23 1996 1061 1066
-
(1996)
Hepatology
, vol.23
, pp. 1061-1066
-
-
Kartenbeck, J.1
Leuschner, U.2
Mayer, R.3
Keppler, D.4
-
46
-
-
0029849789
-
The canalicular conjugate export pump encoded by the cmrp/cmoat gene
-
D. Keppler, and J. Kartenbeck The canalicular conjugate export pump encoded by the cmrp/cmoat gene Prog. Liver Dis. 14 1996 55 67
-
(1996)
Prog. Liver Dis.
, vol.14
, pp. 55-67
-
-
Keppler, D.1
Kartenbeck, J.2
-
47
-
-
0030994468
-
Mutation in the human canalicular multispecific organic anion transporter gene causes the Dubin-Johnson syndrome
-
C.C. Paulusma, M. Kool, P.J. Bosma, G.L. Scheffer, F. Ter Borg, and R.J. Scheper Mutation in the human canalicular multispecific organic anion transporter gene causes the Dubin-Johnson syndrome Hepatology 25 1997 1539 1542
-
(1997)
Hepatology
, vol.25
, pp. 1539-1542
-
-
Paulusma, C.C.1
Kool, M.2
Bosma, P.J.3
Scheffer, G.L.4
Ter Borg, F.5
Scheper, R.J.6
-
48
-
-
0032842748
-
Exon-intron organization of the human multidrug-resistance protein 2 (MRP2) gene mutated in Dubin-Johnson syndrome
-
H. Tsujii, J. Konig, D. Rost, B. Stockel, U. Leuschner, and D. Keppler Exon-intron organization of the human multidrug-resistance protein 2 (MRP2) gene mutated in Dubin-Johnson syndrome Gastroenterology 117 1999 653 660
-
(1999)
Gastroenterology
, vol.117
, pp. 653-660
-
-
Tsujii, H.1
Konig, J.2
Rost, D.3
Stockel, B.4
Leuschner, U.5
Keppler, D.6
-
49
-
-
6844250107
-
Mutations in the canilicular multispecific organic anion transporter (cMOAT) gene, a novel ABC transporter, in patients with hyperbilirubinemia II/Dubin-Johnson syndrome
-
M. Wada, S. Toh, K. Taniguchi, T. Nakamura, T. Uchiumi, and K. Kohno Mutations in the canilicular multispecific organic anion transporter (cMOAT) gene, a novel ABC transporter, in patients with hyperbilirubinemia II/Dubin-Johnson syndrome Hum. Mol. Genet. 7 1998 203 207
-
(1998)
Hum. Mol. Genet.
, vol.7
, pp. 203-207
-
-
Wada, M.1
Toh, S.2
Taniguchi, K.3
Nakamura, T.4
Uchiumi, T.5
Kohno, K.6
-
50
-
-
0035989612
-
A new mutation of the ATP-binding cassette, sub-family C, member 2 (ABCC2) gene in a Japanese patient with Dubin-Johnson syndrome
-
G. Tate, M. Li, T. Suzuki, and T. Mitsuya A new mutation of the ATP-binding cassette, sub-family C, member 2 (ABCC2) gene in a Japanese patient with Dubin-Johnson syndrome Genes Genet. Syst. 77 2002 117 121
-
(2002)
Genes Genet. Syst.
, vol.77
, pp. 117-121
-
-
Tate, G.1
Li, M.2
Suzuki, T.3
Mitsuya, T.4
-
51
-
-
0033652766
-
Impaired protein maturation of the conjugate export pump multidrug resistance protein 2 as a consequence of a deletion mutation in Dubin-Johnson syndrome
-
V. Keitel, J. Kartenbeck, A.T. Nies, H. Spring, M. Brom, and D. Keppler Impaired protein maturation of the conjugate export pump multidrug resistance protein 2 as a consequence of a deletion mutation in Dubin-Johnson syndrome Hepatology 32 2000 1317 1328
-
(2000)
Hepatology
, vol.32
, pp. 1317-1328
-
-
Keitel, V.1
Kartenbeck, J.2
Nies, A.T.3
Spring, H.4
Brom, M.5
Keppler, D.6
-
52
-
-
0035813178
-
Identification and functional analysis of two novel mutations in the multidrug resistance protein 2 gene in Israeli patients with Dubin-Johnson syndrome
-
R. Mor-Cohen, A. Zivelin, N. Rosenberg, M. Shani, S. Muallem, and U. Seligsohn Identification and functional analysis of two novel mutations in the multidrug resistance protein 2 gene in Israeli patients with Dubin-Johnson syndrome J. Biol. Chem. 276 2001 36923 36930
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 36923-36930
-
-
Mor-Cohen, R.1
Zivelin, A.2
Rosenberg, N.3
Shani, M.4
Muallem, S.5
Seligsohn, U.6
-
53
-
-
0036830243
-
Trafficking-defect and functional-defect by mutations of the ATP-binding domains in multidrug resistance protein 2 in patients with Dubin-Johnson syndrome
-
K. Hashimoto, T. Uchiumi, T. Konno, T. Ebihara, T. Nakamura, and M. Wada Trafficking-defect and functional-defect by mutations of the ATP-binding domains in multidrug resistance protein 2 in patients with Dubin-Johnson syndrome Hepatology 36 2002 1236 1245
-
(2002)
Hepatology
, vol.36
, pp. 1236-1245
-
-
Hashimoto, K.1
Uchiumi, T.2
Konno, T.3
Ebihara, T.4
Nakamura, T.5
Wada, M.6
-
54
-
-
0033016291
-
The ubiquitin-proteasome pathway and pathogenesis of human diseases
-
A.L. Schwartz, and A. Ciechanover The ubiquitin-proteasome pathway and pathogenesis of human diseases Ann. Rev. Med. 50 1999 57 74
-
(1999)
Ann. Rev. Med.
, vol.50
, pp. 57-74
-
-
Schwartz, A.L.1
Ciechanover, A.2
-
56
-
-
0029124166
-
P-glycoprotein is stably inhibited by vanadate-induced trapping of nucleotide at a single catalytic site
-
I.L. Urbatsch, B. Sankaran, J. Weber, and A.E. Senior P-glycoprotein is stably inhibited by vanadate-induced trapping of nucleotide at a single catalytic site J. Biol. Chem. 270 1995 19383 19390
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 19383-19390
-
-
Urbatsch, I.L.1
Sankaran, B.2
Weber, J.3
Senior, A.E.4
-
57
-
-
0034724680
-
Comparison of the functional characteristics of the nucleotide binding domains of multidrug resistance protein 1
-
M. Gao, H.R. Cui, D.W. Loe, C.E. Grant, K.C. Almquist, and S.P.C. Cole Comparison of the functional characteristics of the nucleotide binding domains of multidrug resistance protein 1 J. Biol. Chem. 275 2000 13098 13108
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 13098-13108
-
-
Gao, M.1
Cui, H.R.2
Loe, D.W.3
Grant, C.E.4
Almquist, K.C.5
Cole, S.P.C.6
-
58
-
-
0034625350
-
Nonequivalent nucleotide trapping in the two nucleotide binding folds of the human multidrug resistance protein MRP1
-
K. Nagata, M. Nishitani, M. Matsuo, N. Kioka, T. Amachi, and K. Ueda Nonequivalent nucleotide trapping in the two nucleotide binding folds of the human multidrug resistance protein MRP1 J. Biol. Chem. 275 2000 17626 17630
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 17626-17630
-
-
Nagata, K.1
Nishitani, M.2
Matsuo, M.3
Kioka, N.4
Amachi, T.5
Ueda, K.6
-
59
-
-
0032542358
-
Crystal structure of the ATP-binding subunit of an ABC transporter
-
L.W. Hung, I.X. Wang, K. Nikaido, P.Q. Liu, G.F. Ames, and S.H. Kim Crystal structure of the ATP-binding subunit of an ABC transporter Nature 396 1998 703 707
-
(1998)
Nature
, vol.396
, pp. 703-707
-
-
Hung, L.W.1
Wang, I.X.2
Nikaido, K.3
Liu, P.Q.4
Ames, G.F.5
Kim, S.H.6
-
60
-
-
0027995444
-
Detection of more than 50 different CFTR mutations in a large group of German cystic fibrosis patients
-
T. Dork, F. Mekus, K. Schmidt, J. Bosshammer, R. Fislage, and T. Heuer Detection of more than 50 different CFTR mutations in a large group of German cystic fibrosis patients Hum. Genet. 94 1994 533 542
-
(1994)
Hum. Genet.
, vol.94
, pp. 533-542
-
-
Dork, T.1
Mekus, F.2
Schmidt, K.3
Bosshammer, J.4
Fislage, R.5
Heuer, T.6
-
61
-
-
0034669176
-
Crystal structure of MalK, the ATPase subunit of the trehalose/maltose ABC transporter of the archaeon thermococcus litoralis
-
K. Diederichs, J. Diez, G. Greller, C. Muller, J. Breed, and C. Schrell Crystal structure of MalK, the ATPase subunit of the trehalose/maltose ABC transporter of the archaeon thermococcus litoralis Eur. Mol. Biol. Org. J. 19 2000 5951 5961
-
(2000)
Eur. Mol. Biol. Org. J.
, vol.19
, pp. 5951-5961
-
-
Diederichs, K.1
Diez, J.2
Greller, G.3
Muller, C.4
Breed, J.5
Schrell, C.6
-
62
-
-
0032545447
-
A splice mutation in the human canalicular multispecific organic anion transporter gene causes Dubin-Johnson syndrome
-
S. Kajihara, A. Hisatomi, T. Mizuta, T. Hara, I. Ozaki, and I. Wada A splice mutation in the human canalicular multispecific organic anion transporter gene causes Dubin-Johnson syndrome Biochem. Biophys. Res. Commun. 253 1998 454 457
-
(1998)
Biochem. Biophys. Res. Commun.
, vol.253
, pp. 454-457
-
-
Kajihara, S.1
Hisatomi, A.2
Mizuta, T.3
Hara, T.4
Ozaki, I.5
Wada, I.6
-
63
-
-
16944363733
-
Nuclear localization and increased levels of transcription factor YB-1 in primary human breast cancers are associated with intrinsic MDR1 gene expression
-
R.C. Bargou, K. Jurchott, C. Wagener, S. Bergmann, S. Metzner, and K. Bommert Nuclear localization and increased levels of transcription factor YB-1 in primary human breast cancers are associated with intrinsic MDR1 gene expression Nat. Med. 3 1997 447 450
-
(1997)
Nat. Med.
, vol.3
, pp. 447-450
-
-
Bargou, R.C.1
Jurchott, K.2
Wagener, C.3
Bergmann, S.4
Metzner, S.5
Bommert, K.6
-
64
-
-
0032513246
-
Direct involvement of the Y-box binding protein YB-1 in genotoxic stress-induced activation of the human multidrug resistance 1 gene
-
T. Ohga, T. Uchiumi, Y. Makino, K. Koike, M. Wada, and M. Kuwano Direct involvement of the Y-box binding protein YB-1 in genotoxic stress-induced activation of the human multidrug resistance 1 gene J. Biol. Chem. 273 1998 5997 6000
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 5997-6000
-
-
Ohga, T.1
Uchiumi, T.2
Makino, Y.3
Koike, K.4
Wada, M.5
Kuwano, M.6
-
65
-
-
0034021716
-
Alu-associated interstitial deletions and chromosomal re-arrangement in 2 human multidrug-resistant cell lines
-
T. Harada, J. Nagayama, K. Kohno, L.A. Mickley, T. Fojo, and M. Kuwano Alu-associated interstitial deletions and chromosomal re-arrangement in 2 human multidrug-resistant cell lines Int. J. Cancer 86 2000 506 511
-
(2000)
Int. J. Cancer
, vol.86
, pp. 506-511
-
-
Harada, T.1
Nagayama, J.2
Kohno, K.3
Mickley, L.A.4
Fojo, T.5
Kuwano, M.6
-
66
-
-
0033564370
-
Association of 5′ CpG demethylation and altered chromatin structure in the promoter region with transcriptional activation of the multidrug resistance 1 gene in human cancer cells
-
H. Kusaba, M. Nakayama, T. Harada, M. Nomoto, K. Kohno, and M. Kuwano Association of 5′ CpG demethylation and altered chromatin structure in the promoter region with transcriptional activation of the multidrug resistance 1 gene in human cancer cells Eur. J. Biochem. 262 1999 924 932
-
(1999)
Eur. J. Biochem.
, vol.262
, pp. 924-932
-
-
Kusaba, H.1
Nakayama, M.2
Harada, T.3
Nomoto, M.4
Kohno, K.5
Kuwano, M.6
-
67
-
-
0032403478
-
Hypomethylation status of CpG sites at the promoter region and overexpression of the human MDR1 gene in acute myeloid leukemias
-
M. Nakayama, M. Wada, T. Harada, J. Nagayama, H. Kusaba, and K. Ohshima Hypomethylation status of CpG sites at the promoter region and overexpression of the human MDR1 gene in acute myeloid leukemias Blood 92 1998 4296 4307
-
(1998)
Blood
, vol.92
, pp. 4296-4307
-
-
Nakayama, M.1
Wada, M.2
Harada, T.3
Nagayama, J.4
Kusaba, H.5
Ohshima, K.6
-
68
-
-
0034351878
-
MDR1 gene overexpression and altered degree of methylation at the promoter region in bladder cancer during chemotherapeutic treatment
-
Y. Tada, M. Wada, K. Kuroiwa, N. Kinugawa, T. Harada, and J. Nagayama MDR1 gene overexpression and altered degree of methylation at the promoter region in bladder cancer during chemotherapeutic treatment Clin. Cancer Res. 6 2000 4618 4627
-
(2000)
Clin. Cancer Res.
, vol.6
, pp. 4618-4627
-
-
Tada, Y.1
Wada, M.2
Kuroiwa, K.3
Kinugawa, N.4
Harada, T.5
Nagayama, J.6
-
69
-
-
0023447098
-
Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues
-
F. Thiebaut, T. Tsuruo, H. Hamada, M.M. Gottesman, I. Pastan, and M.C. Willingham Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues Proc. Natl Acad. Sci. USA 84 1987 7735 7738
-
(1987)
Proc. Natl Acad. Sci. USA
, vol.84
, pp. 7735-7738
-
-
Thiebaut, F.1
Tsuruo, T.2
Hamada, H.3
Gottesman, M.M.4
Pastan, I.5
Willingham, M.C.6
-
70
-
-
0023889448
-
Tissue distribution of P-glycoprotein encoded by a multidrug-resistant gene as revealed by a monoclonal antibody, MRK 16
-
I. Sugawara, I. Kataoka, Y. Morishita, H. Hamada, T. Tsuruo, and S. Itoyama Tissue distribution of P-glycoprotein encoded by a multidrug-resistant gene as revealed by a monoclonal antibody, MRK 16 Cancer Res. 48 1988 1926 1929
-
(1988)
Cancer Res.
, vol.48
, pp. 1926-1929
-
-
Sugawara, I.1
Kataoka, I.2
Morishita, Y.3
Hamada, H.4
Tsuruo, T.5
Itoyama, S.6
-
71
-
-
0000712439
-
Multidrug-resistance gene (P-glycoprotein) is expressed by endothelial cells at blood-brain barrier sites
-
C. Cordon-Cardo, J.P. OlBrien, D. Casals, L. Rittman-Grauer, J.L. Biedler, and M.R. Melamed Multidrug-resistance gene (P-glycoprotein) is expressed by endothelial cells at blood-brain barrier sites Proc. Natl. Acad. Sci. USA 86 1989 695 698
-
(1989)
Proc. Natl. Acad. Sci. USA
, vol.86
, pp. 695-698
-
-
Cordon-Cardo, C.1
Olbrien, J.P.2
Casals, D.3
Rittman-Grauer, L.4
Biedler, J.L.5
Melamed, M.R.6
-
72
-
-
4243801613
-
Normal viability and altered pharmacokinetics in mice lacking mdr1-type (drug-transporting) P-glycoproteins
-
A.H. Schinkel, U. Mayer, E. Wagenaar, C.A. Mol, L. Van Deemter, and J.J. Smit Normal viability and altered pharmacokinetics in mice lacking mdr1-type (drug-transporting) P-glycoproteins Proc. Natl Acad. Sci. USA 94 1997 4028 4033
-
(1997)
Proc. Natl Acad. Sci. USA
, vol.94
, pp. 4028-4033
-
-
Schinkel, A.H.1
Mayer, U.2
Wagenaar, E.3
Mol, C.A.4
Van Deemter, L.5
Smit, J.J.6
-
73
-
-
0031982725
-
Pharmacological insights from P-glycoprotein knockout mice
-
A.H. Schinkel Pharmacological insights from P-glycoprotein knockout mice Int. J. Clin. Pharmacol. Ther. 36 1998 9 13
-
(1998)
Int. J. Clin. Pharmacol. Ther.
, vol.36
, pp. 9-13
-
-
Schinkel, A.H.1
-
74
-
-
0032900953
-
Biochemical, cellular, and pharmacological aspects of the multidrug transporter
-
S.V. Ambudkar, S. Dey, C.A. Hrycyna, M. Ramachandra, I. Pastan, and M.M. Gottesman Biochemical, cellular, and pharmacological aspects of the multidrug transporter Annu. Rev. Pharmacol. Toxicol. 39 1999 361 398
-
(1999)
Annu. Rev. Pharmacol. Toxicol.
, vol.39
, pp. 361-398
-
-
Ambudkar, S.V.1
Dey, S.2
Hrycyna, C.A.3
Ramachandra, M.4
Pastan, I.5
Gottesman, M.M.6
-
75
-
-
0342762062
-
The barrier function of CYP3A4 and P-glycoprotein in the small bowel
-
P.B. Watkins The barrier function of CYP3A4 and P-glycoprotein in the small bowel Adv. Drug Deliv. Rev. 27 1997 161 170
-
(1997)
Adv. Drug Deliv. Rev.
, vol.27
, pp. 161-170
-
-
Watkins, P.B.1
-
76
-
-
0037131893
-
The influence of MDR1 polymorphisms on P-glycoprotein expression and function in humans
-
M.F. Fromm The influence of MDR1 polymorphisms on P-glycoprotein expression and function in humans Adv. Drug Deliv. Rev. 54 2002 1295 1310
-
(2002)
Adv. Drug Deliv. Rev.
, vol.54
, pp. 1295-1310
-
-
Fromm, M.F.1
-
77
-
-
0025071180
-
Expression of the multidrug resistance gene product (P-glycoprotein) in human normal and tumor tissues
-
C. Cordon-Cardo, J.P. OlBrien, J. Boccia, D. Casals, J.R. Bertino, and M.R. Melamed Expression of the multidrug resistance gene product (P-glycoprotein) in human normal and tumor tissues J. Histochem. Cytochem. 38 1990 1277 1287
-
(1990)
J. Histochem. Cytochem.
, vol.38
, pp. 1277-1287
-
-
Cordon-Cardo, C.1
Olbrien, J.P.2
Boccia, J.3
Casals, D.4
Bertino, J.R.5
Melamed, M.R.6
-
78
-
-
0029916534
-
P-glycoprotein: A major determinant of rifampicin-inducible expression of cytochrome P4503A in mice and humans
-
E.G. Schuetz, A.H. Schinkel, M.V. Relling, and J.D. Schuetz P-glycoprotein: a major determinant of rifampicin-inducible expression of cytochrome P4503A in mice and humans Proc. Natl Acad. Sci. USA 93 1996 4001 4005
-
(1996)
Proc. Natl Acad. Sci. USA
, vol.93
, pp. 4001-4005
-
-
Schuetz, E.G.1
Schinkel, A.H.2
Relling, M.V.3
Schuetz, J.D.4
-
79
-
-
0032754284
-
The role of intestinal P-glycoprotein in the interaction of digoxin and rifampin
-
B. Greiner, M. Eichelbaum, P. Fritz, H.P. Kreichgauer, O. Von Richter, and J. Zundler The role of intestinal P-glycoprotein in the interaction of digoxin and rifampin J. Clin. Invest. 104 1999 147 153
-
(1999)
J. Clin. Invest.
, vol.104
, pp. 147-153
-
-
Greiner, B.1
Eichelbaum, M.2
Fritz, P.3
Kreichgauer, H.P.4
Von Richter, O.5
Zundler, J.6
-
80
-
-
0030838009
-
The multidrug-resistance P-glycoprotein (Pgp, MDR1) is an early marker of blood-brain barrier development in the microvessels of the developing human brain
-
U. Schumacher, and K. Mollgard The multidrug-resistance P-glycoprotein (Pgp, MDR1) is an early marker of blood-brain barrier development in the microvessels of the developing human brain Histochem. Cell Biol. 108 1997 179 182
-
(1997)
Histochem. Cell Biol.
, vol.108
, pp. 179-182
-
-
Schumacher, U.1
Mollgard, K.2
-
81
-
-
0033616684
-
Choroid plexus epithelialexpression of MDR1 P glycoprotein and multidrug resistance-associated protein contribute to the blood-cerebrospinal fluid drug-permeability barrier
-
V.V. Rao, J.L. Dahlheimer, M.E. Bardgett, A.Z. Snyder, R.A. Finch, and A.C. Sartorelli Choroid plexus epithelialexpression of MDR1 P glycoprotein and multidrug resistance-associated protein contribute to the blood-cerebrospinal fluid drug-permeability barrier Proc. Natl Acad. Sci. USA 96 1999 3900 3905
-
(1999)
Proc. Natl Acad. Sci. USA
, vol.96
, pp. 3900-3905
-
-
Rao, V.V.1
Dahlheimer, J.L.2
Bardgett, M.E.3
Snyder, A.Z.4
Finch, R.A.5
Sartorelli, A.C.6
-
82
-
-
0024576304
-
Immunohistochemical localization in normal tissues of different epitopes in the multidrug transport protein P170: Evidence for localization in brain capillaries and crossreactivity of one antibody with a muscle protein
-
F. Thiebaut, T. Tsuruo, H. Hamada, M.M. Gottesman, I. Pastan, and M.C. Willingham Immunohistochemical localization in normal tissues of different epitopes in the multidrug transport protein P170: evidence for localization in brain capillaries and crossreactivity of one antibody with a muscle protein J. Histochem. Cytochem. 37 1989 159 164
-
(1989)
J. Histochem. Cytochem.
, vol.37
, pp. 159-164
-
-
Thiebaut, F.1
Tsuruo, T.2
Hamada, H.3
Gottesman, M.M.4
Pastan, I.5
Willingham, M.C.6
-
83
-
-
0034046035
-
Increased expression of an ATP-binding cassette superfamily transporter, multidrug resistance protein 2, in human colorectal carcinomas
-
E. Hinoshita, T. Uchiumi, K. Taguchi, N. Kinukawa, M. Tsuneyoshi, and Y. Maehara Increased expression of an ATP-binding cassette superfamily transporter, multidrug resistance protein 2, in human colorectal carcinomas Clin. Cancer Res. 6 2000 2401 2407
-
(2000)
Clin. Cancer Res.
, vol.6
, pp. 2401-2407
-
-
Hinoshita, E.1
Uchiumi, T.2
Taguchi, K.3
Kinukawa, N.4
Tsuneyoshi, M.5
Maehara, Y.6
-
84
-
-
0026500180
-
The function of Gp170, the multidrug-resistance gene product, in the brush border of rat intestinal mucosa
-
S. Hsing, Z. Gatmaitan, and I.M. Arias The function of Gp170, the multidrug-resistance gene product, in the brush border of rat intestinal mucosa Gastroenterology 102 1992 879 885
-
(1992)
Gastroenterology
, vol.102
, pp. 879-885
-
-
Hsing, S.1
Gatmaitan, Z.2
Arias, I.M.3
-
85
-
-
0033958086
-
Multiple physiological functions for multidrug transporter P-glycoprotein?
-
R.W. Johnstone, A.A. Ruefli, and M.J. Smyth Multiple physiological functions for multidrug transporter P-glycoprotein? Trends Biochem. Sci. 25 2000 1 6
-
(2000)
Trends Biochem. Sci.
, vol.25
, pp. 1-6
-
-
Johnstone, R.W.1
Ruefli, A.A.2
Smyth, M.J.3
-
86
-
-
0025739785
-
Relationship of the expression of the multidrug resistance gene product (P- glycoprotein) in human colon carcinoma to local tumor aggressiveness and lymph node metastasis
-
R.S. Weinstein, S.M. Jakate, J.M. Dominguez, M.D. Lebovitz, G.K. Koukoulis, and J.R. Kuszak Relationship of the expression of the multidrug resistance gene product (P- glycoprotein) in human colon carcinoma to local tumor aggressiveness and lymph node metastasis Cancer Res. 51 1991 2720 2726
-
(1991)
Cancer Res.
, vol.51
, pp. 2720-2726
-
-
Weinstein, R.S.1
Jakate, S.M.2
Dominguez, J.M.3
Lebovitz, M.D.4
Koukoulis, G.K.5
Kuszak, J.R.6
-
87
-
-
1542399109
-
Effect of PSC 833, an inhibitor of P-glycoprotein on N-methyl-N- nitrosourea induced mammary carcinogenesis in rats
-
J. Kankesan, R. Vanama, A. Yusuf, J.J. Thiessen, V. Ling, and P.M. Rao Effect of PSC 833, an inhibitor of P-glycoprotein on N-methyl-N-nitrosourea induced mammary carcinogenesis in rats Carcinogenesis 25 2004 425 430
-
(2004)
Carcinogenesis
, vol.25
, pp. 425-430
-
-
Kankesan, J.1
Vanama, R.2
Yusuf, A.3
Thiessen, J.J.4
Ling, V.5
Rao, P.M.6
-
88
-
-
10744231610
-
Effect of PSC 833, an inhibitor of P-glycoprotein, on 1,2-dimethylhydrazine-induced liver carcinogenesis in rats
-
J. Kankesan, A. Yusuf, E. Laconi, R. Vanama, G. Bradley, and J.J. Thiessen Effect of PSC 833, an inhibitor of P-glycoprotein, on 1,2-dimethylhydrazine-induced liver carcinogenesis in rats Carcinogenesis 24 2003 1977 1984
-
(2003)
Carcinogenesis
, vol.24
, pp. 1977-1984
-
-
Kankesan, J.1
Yusuf, A.2
Laconi, E.3
Vanama, R.4
Bradley, G.5
Thiessen, J.J.6
-
89
-
-
0034724324
-
Functional polymorphisms of the human multidrugresistance gene: Multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo
-
S. Hoffmeyer, O. Burk, O. Von Richter, H.P. Arnold, J. Brockmoller, and A. Johne Functional polymorphisms of the human multidrugresistance gene: multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo Proc. Natl Acad. Sci. USA 97 2000 3473 3478
-
(2000)
Proc. Natl Acad. Sci. USA
, vol.97
, pp. 3473-3478
-
-
Hoffmeyer, S.1
Burk, O.2
Von Richter, O.3
Arnold, H.P.4
Brockmoller, J.5
Johne, A.6
-
90
-
-
1942467691
-
Genetic polymorphism at the 5′ regulatory region of MDR1 and its association with inter-individual variation of expression level in colon
-
S. Taniguchi, Y. Mochida, T. Uchiumi, T. Tahira, K. Hayashi, and K. Takagi Genetic polymorphism at the 5′ regulatory region of MDR1 and its association with inter-individual variation of expression level in colon Mol. Cancer Ther. 2 2003 1351 1359
-
(2003)
Mol. Cancer Ther.
, vol.2
, pp. 1351-1359
-
-
Taniguchi, S.1
Mochida, Y.2
Uchiumi, T.3
Tahira, T.4
Hayashi, K.5
Takagi, K.6
-
91
-
-
0142024010
-
Homozygous mutation Arg768Trp in the ABC-transporter encoding gene MRP2/cMOAT/ABCC2 causes Dubin-Johnson syndrome in a caucasian patient
-
V. Materna, and H. Lage Homozygous mutation Arg768Trp in the ABC-transporter encoding gene MRP2/cMOAT/ABCC2 causes Dubin-Johnson syndrome in a caucasian patient J. Hum. Genet. 48 2003 484 486
-
(2003)
J. Hum. Genet.
, vol.48
, pp. 484-486
-
-
Materna, V.1
Lage, H.2
-
92
-
-
0141867789
-
Identification of a novel 2026G→C mutation of the MRP2 gene in a Japanese patient with Dubin-Johnson syndrome
-
S. Wakusawa, I. Machida, S. Suzuki, H. Hayashi, M. Yano, and K. Yoshioka Identification of a novel 2026G→C mutation of the MRP2 gene in a Japanese patient with Dubin-Johnson syndrome J. Hum. Genet. 48 2003 425 429
-
(2003)
J. Hum. Genet.
, vol.48
, pp. 425-429
-
-
Wakusawa, S.1
MacHida, I.2
Suzuki, S.3
Hayashi, H.4
Yano, M.5
Yoshioka, K.6
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