Purification and characterization of L,(L/D)-aminopeptidase from guinea pig serum

Preparative Biochemistry and Biotechnology

Volumn 36, Issue 2, 2006, Pages 175-195

  Krstanović, Marina ^a,c   Brgles, Marija ^a   Halassy, Beata ^a   Frkanec, Ruža ^a   Vrdoljak, Anto ^a   Branović, Karmen ^a   Tomašić, Jelka ^a   Benedetti, Fabio ^b  

^a INSTITUTE OF IMMUNOLOGY   (Croatia)

^b UNIVERSITY OF TRIESTE   (Italy)

^c Belupo Pharmaceuticals and Cosmetics   (Croatia)

Author keywords

Guinea pig serum; L,(L D) Aminopeptidase; Mammalian sera; N Acetylmuramyl L alanine amidase (EC 3.5.1.28); Peptidoglycan monomer

Indexed keywords

ALANINE; AMINOPEPTIDASE; OLIGOPEPTIDE; PEPTIDOGLYCAN; PROTEINASE INHIBITOR;

AMINO ACID SEQUENCE; ANIMAL; ARTICLE; BLOOD; CHEMISTRY; ENZYME SPECIFICITY; GUINEA PIG; ISOLATION AND PURIFICATION; METABOLISM; MOLECULAR WEIGHT; OXIDATION REDUCTION REACTION; PH;

ALANINE; AMINO ACID SEQUENCE; AMINOPEPTIDASES; ANIMALS; GUINEA PIGS; HYDROGEN-ION CONCENTRATION; MOLECULAR WEIGHT; OLIGOPEPTIDES; OXIDATION-REDUCTION; PEPTIDOGLYCAN; PROTEASE INHIBITORS; SUBSTRATE SPECIFICITY;

CAVIA PORCELLUS; MAMMALIA;

EID: 33644806187     PISSN: 10826068     EISSN: 15322297     Source Type: Journal    
DOI: 10.1080/10826060500534099     Document Type: Article

References (43)

1. Höltje, J.V. Cell walls, bacterial. In Encyclopedia of Microbiology, 2nd Ed.; Oliver, S.G., Schaechter, M., Lederberg, J., Alexander, M., Bloom, B.R., Hopwood, D.A., Hull, R., Iglewski, B.H., Laskin, A.I., Eds.; Academic Press: Amsterdam, 2000; Vol. 1, 759-771.
2. Tomasz, A. Building and breaking of bonds in the cell wall of bacteria - The role for autolysins. In Microbial Cell Wall Synthesis and Autolysis; Nombela, C., Ed.; Elsevier Science Publishing: New York, 1984; 3-12.
3. Shockman, G.D.; Höltje, J.V. Microbial peptidoglycan (Murein) hydrolases. In Bacterial Cell Wall; Ghuysen, J.M., Hakenbeck, R., Eds.; Elsevier: Amsterdam, 1994; 131-166.
4. Seidl, P.H.; Schleifer, K.H. Biological Properties of Peptidoglycans; Walter de Gruyter: Berlin, New York, 1986.
5. Keglević, D.; Ladešić, B.; Hadžija, O.; Tomašić, J.; Valinger, Z.; Pokorny, M.; Naumski, R. Isolation and study of the composition of a peptidoglycan complex excreted by the biotin-requiring mutant of Brevibacterium divaricatum NRRL-2311 in the presence of penicillin. Eur. J. Biochem. 1974, 42, 389-400.
6. Keglević, D.; Ladešić, B.; Tomašić, J.; Valinger, Z.; Naumski, R. Isolation procedure and properties of monomer unit from lysozyme digest of peptidoglycan complex excreted into the medium by penicillin-treated Brevibacterium divaricatum mutant. Biochim. Biophys. Acta 1979, 585, 273-281.
7. Tomašić, J.; Sesartić, Lj.; Martin, S.A.; Valinger, Z.; Ladešić, B. Comparative susceptibility of peptidoglycan monomer from Brevibacterium divaricatum and its anhydromuramyl analogue to hydrolysis with N-acetilmuramyl-L-alanine amidase; isolation and characterization of anhydromuramyl-peptidoglycan. J. Chromatogr. 1988, 440, 405-414.
8. Matter, H.; Szilagy, L.; Forgo, P.; Marinić, Ž.; Klaić, B. Structure and dynamics of a peptidoglycan monomer in aqueous solution using NMR spectroscopy and simulated annealing calculations. J. Am. Chem. Soc. 1997, 119, 2212-2223.
9. Tomašić, J.; Hršak, I. Peptidoglycan monomer originating from Brevibacterium divaricatum - its metabolism and biological activities in the host. In Surface Structures of Microorganisms and Their Interactions with Mammalian Host; Shrinner, E., Richmond, M.H., Seibert, G., Schwartz, G., Eds.; VCH: Weinheim, 1988; 113-121.
10. Tomašić, J.; Hanzl-Dujmović, I.; Špoljar, B.; Vranešić, B.; Šantak, M.; Jovičić, A. Comparative study of the effects of peptidoglycan monomer and structurally related adamantyltripeptides on humoral immune response to ovalbumin in mouse. Vaccine 2000, 18, 1236-1243.
11. 14C-labeled peptidoglycan monomer in mice. I. Identification of the monomer and corresponding pentapeptide in urine. Biochim. Biophys. Acta 1980, 629, 77-82.
12. 14C-labeled immunoadjuvant peptidoglycan monomer. II. In vitro studies. Biochim. Biophys. Acta 1981, 678, 12-17.
13. Valinger, Z.; Ladešić, B.; Tomašić, J. Partial purification and characterization of N-acetylmuramyl-L-alanine amidase from human and mouse serum. Biochim. Biophys. Acta 1982, 701, 63-71.
14. Mollner, S.; Braun, V. Murein hydrolase (N-acetylmuramyl-L-alanine amidase) in human serum. Arch. Microbiol. 1984, 140, 171-177.
15. Vanderwinkel, E.; De Vlieghere, M.; De Pauw, P.; Cattalini, N.; Ledoux, V.; Gigot, D.; Ten Have, J.P. Purification and characterization of N-acetylmuramyl-L-alanine amidase from human serum. Biochim. Biophys. Acta 1990, 1039, 331-338.
16. Hoijer, M.A.; Meleif, M.J.; Keck, W.; Hazenberg, M.P. Purification and characterization of N-acetylmuramyl-L-alanine amidase from human plasma using monoclonal antibodies. Biochim. Biophys. Acta 1996, 1289, 57-64.
17. Lowry, O.H.; Rosebrough, N.J.; Farr, A.L.; Randal, R.J. Protein measurement with the Folin reagent. J. Biol. Chem. 1951, 193, 265-275.
18. Krstanović, M.; Frkanec, R.; Vranešić, B.; Ljevaković, D.; Šporec, V.; Tomašić, J. Reversed-phase high-performance liquid chromatographic method for the determination of peptidoglycan monomers and structurally related peptides and adamantyltripeptides. J. Chromatogr. B 2002, 773, 167-174.
19. Halassy, B.; Krstanović, M.; Frkanec, R.; Tomašić, J. Adjuvant activity of peptidoglycan monomer and its metabolic products. Vaccine 2003, 21, 971-976.
20. Jung, K.; Scholz, D. An optimized assay of alanine aminopeptidase activity in urine. Clin. Chem. 1980, 26, 1251-1254.
21. Heukeshoven, J.; Dernick, R. Simplified method for silver staining of proteins in polyacrylamide gels and the mechanism of silver staining. Electrophoresis 1985, 6, 103-112.
22. Hoijer, M.A.; Melief, M.J.; Calafat, J.; Roos, D.; Van den Beemd, R.W.M.; Dongen, J.J.M.; Hazenberg, M.P. Expression and intracellular localization of the human N-acetylmuramyl-L-alanine amidase, a bacterial cell wall-degrading enzyme. Blood 1997, 90, 1246-1254.
23. Hoijer, M.A.; Melief, M.J.; Debets, R.; Hazenberg, M.P. Inflammatory properties of peptidoglycan are decreased after degradation by human N-acetylmuramyl-L-alanine amidase. Eur. Cytokine Network 1997, 8, 375-381.
24. Hoijer, M.A.; de Groot, R.; van Lieshout, L.; Jacobs, B.C.; Melief, M.J.; Hazenberg, M.P. Differences in N-acetylmuramyl-L-alanine amidase and lysozyme in serum and cerebrospinal fluid of patients with bacterial meningitis. J. Infect. Dis. 1998, 177, 102-106.
25. Assano, Y.; Lübbehüsen, T.L. Enzymes acting on peptides containing D-amino acid. J. Biosci. Bioeng. 2000, 89, 295-306.
26. Romies, T.; Höltje, J.V. Penicilin-binding protein 7/8 of Escherichia coli is a D,D-endopeptidase. Eur. J. Biochem. 1994, 224, 597-604.
27. Tomioka, S.; Matsuhashi, M. Purification of penicillin-insensitive D,D-endopeptidase: a new cell wall peptidoglycan-hydrolyzing enzyme in Escherichia coli, and its inhibition by deoxyribonucleic acids. Biochem. Biophys. Res. Commun. 1978, 84, 978-984.
28. Arminjon, F.; Guinand, M.; Vacheron, M.J.; Michel, G. Specificity profiles of the membrane-bound γ-D-glutamyl-(L)meso-diaminopimelate endopeptidase and L,D-carboxypeptidase from Bacillus sphearicus 9602. Eur. J. Biochem. 1977, 73, 557-565.
29. Vacheron, M.J.; Guinand, M.; Francon, A.; Michel, G. Characterization of a new endopeptidase from sporulating Bacillus sphearicus which is specific for the γ-D-glutamyl-L-lysine and γ-D-glutamyl-(L)meso-diaminopimelate linkages of peptidoglycan substrates. Eur. J. Biochem. 1979, 100, 189-196.
30. Garnier, M.; Vacheron, M.J.; Guinand, M.; Michel, G. Purification and partial characterization of the extracellular γ-D-glutamyl-(L)meso- diaminopimelate endopeptidase I from Bacillus sphearicus NCTC 9602. Eur. J. Biochem. 1985, 148, 539-543.
31. Loessner, M.J.; Wendlinger, G.; Scherer, S. Heterogeneous endolysins in Listeria monocytogenes bacteriophages: a new class of enzymes and evidence for conserved holin genes within the siphoviral lysis cassettes. Mol. Microbiol. 1995, 16, 1231-1241.
32. Metz, R.; Henning, S.; Hammes, W.P. L,D-Carboxypeptidase activity in Escherichia coli. I. The L,D-carboxypeptidase activity in ether treated cells. Arch. Microbiol. 1986, 144, 175-186.
33. Ursins, A.; Steinhaus, H.; Höltje, J.V. Purification of a nocardicin A-sensitive L,D-carboxypeptidase from Escherichia coli by affinity chromatography. J. Bacteriol. 1992, 174, 441-446.
34. Höltje, J.V. From growth to autolysis: the murein hydrolases in Escherichia coli. Arch. Microbiol. 1995, 164, 243-254.
35. Vollmer, W.; Höltje, J.V. Morphogenesis of Escherichia coli. Curr. Opin. Microbiol. 2001, 4, 625-633.
36. Park, J.T. The murein sacculus. In Escherichia coli and Salmonella; Neidhardt, F.C., Ed.; ASM Press: Washington, 1996; 48-57.
37. Höltje, J.V.; Heidrich, C. Enzymology of elongation and constriction of the murein sacculus of Escherichia coli. Biochimie 2001, 83, 103-108.
38. Uehara, T.; Park, J.T. Identification of MpaA, an amidase in Escherichia coli that hydrolyzes the γ-D-glutamyl-meso-diaminopimelate bond in murein peptides. J. Bacteriol. 2003, 185, 679-682.
39. Asano, Y.; Nakazawa, A.; Kato, Y.; Kondo, K. Properties of novel D-stereospecific aminopeptidase from Ochrobactrum anthropi. J. Biol. Chem. 1989, 264, 14233-14239.
40. Komeda, H.; Asano, Y. Gene cloning, nucleotide sequencing, and purification and characterization of the stereospecific amino acid amidase from Ochrobactrum anthropi SV3. Eur. J. Biochem. 2000, 267, 2028-2035.
41. Campbell, B.J.; Lin, Y-C.; Davis, R.V.; Ballew, E. The purification and properties of a particulate renal dipeptidase. Biochim. Biophys. Acta 1965, 118, 371-386.
42. Watanabe, T.; Kera, Y.; Matsumoto, T.; Yamada, R. Purification and kinetic properties of a D-amino acid peptide hydrolyzing enzyme from pig kidney cortex and its tentative identification with renal membrane dipeptidase. Biochim. Biophys. Acta 1996, 1298, 109-118.
43. Shimumara, M.; Hazato, T.; Katayama, T. Purification and characterization of an enkephalin-degrading aminopeptidase from guinea pig serum. Biochim. Biophys. Acta 1984, 798, 8-13.