Immobilization of an anticoagulant benzamidine derivative: Effect of spacer arms and carrier hydrophobicity on thrombin binding

Acta Biomaterialia

Volumn 1, Issue 4, 2005, Pages 441-449

  Salchert, Katrin ^a   Gouzy, Marie Françoise ^a   Glorius, Maja ^a   Kühn, Anett ^a   Nitschke, Mirko ^a   Werner, Carsten ^a,b  

^a LEIBNIZ INSTITUTE OF POLYMER RESEARCH DRESDEN   (Germany)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

Benzamidine; Maleic anhydride copolymers; PEG; Thrombin

Indexed keywords

BIOMEDICAL EQUIPMENT; COAGULATION; EFFICIENCY; ENZYMES; HYDROPHOBICITY; MOLECULES; POLYETHYLENE OXIDES; POLYETHYLENES;

BENZAMIDINE; BENZAMIDINE DERIVATIVES; BLOOD COAGULATION; DERIVATIZATIONS; IMMOBILISATION; MALEIC ANHYDRIDE COPOLYMERS; MATERIAL'S SURFACE; MEDICAL DEVICES; SPACER ARMS; THROMBIN BINDING;

POLYETHYLENE GLYCOLS;

AMIDINE; AMINO ACID DERIVATIVE; ANTICOAGULANT AGENT; BENZAMIDINE DERIVATIVE; BUFFER; CARBOXYL GROUP; CARBROMAL; COPOLYMER; MACROGOL; MALEIC ANHYDRIDE; THROMBIN;

ADSORPTION; ANTICOAGULATION; ARTICLE; CARBOXY TERMINAL SEQUENCE; CHEMICAL INTERACTION; CHEMICAL STRUCTURE; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; COVALENT BOND; DERIVATIZATION; ENZYME IMMOBILIZATION; FILM; HYDROPHILICITY; HYDROPHOBICITY; IMMERSION; IMMOBILIZATION; IMMUNOHISTOCHEMISTRY; MATERIAL COATING; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PROTEIN BINDING; X RAY PHOTOELECTRON SPECTROSCOPY;

EID: 33644796190     PISSN: 17427061     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.actbio.2005.04.001     Document Type: Article

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