Instability of clonality in gastric lymphoid infiltrates: A study with emphasis on serial biopsies

American Journal of Surgical Pathology

Volumn 29, Issue 12, 2005, Pages 1582-1592

  Lo, William Y F ^a   Li, Jackson Y W ^a   Chan, Y K ^a   Lai, Lawrence S W ^a   Yeung, Y W ^a   Lo, Stephen T H ^a   Tsui, Wilson M S ^a   Ng, C S ^a  

^a Caritas Medical Centre Hong Kong   (Hong Kong)

Author keywords

Helicobacter pylori; Mucosa associated lymphoid tissue lymphoma; Polymerase chain reaction

Indexed keywords

IMMUNOGLOBULIN HEAVY CHAIN;

ADULT; AGED; ARTICLE; CANCER GRADING; CANCER GROWTH; CELL INFILTRATION; CLINICAL ARTICLE; CLONAL VARIATION; FEMALE; FOLLOW UP; GASTRIC MUCOSAL LYMPHOID INFILTRATE; GASTRITIS; GENE REARRANGEMENT; HELICOBACTER INFECTION; HELICOBACTER PYLORI; HISTOGENESIS; HISTOLOGY; HUMAN; HUMAN TISSUE; LYMPHOID CELL; MALE; MUCOSA ASSOCIATED LYMPHOID TISSUE LYMPHOMA; PATIENT MONITORING; POLYMERASE CHAIN REACTION; SCORING SYSTEM; STOMACH BIOPSY; STOMACH TUMOR; CASE REPORT; CELL CLONE; COMPARATIVE STUDY; CYTOLOGY; DISEASE COURSE; GASTROSCOPY; GENETICS; MICROBIOLOGY; MIDDLE AGED; PATHOLOGY; RETROSPECTIVE STUDY; TIME;

ADULT; AGED; AGED, 80 AND OVER; CLONE CELLS; DISEASE PROGRESSION; FEMALE; FOLLOW-UP STUDIES; GASTRITIS; GASTROSCOPY; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; LYMPHOMA, MUCOSA-ASSOCIATED LYMPHOID TISSUE; MALE; MIDDLE AGED; POLYMERASE CHAIN REACTION; RETROSPECTIVE STUDIES; STOMACH NEOPLASMS; TIME FACTORS;

EID: 33644791310     PISSN: 01475185     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.pas.0000188031.40836.00     Document Type: Article

References (74)

1. Algara P, Martinez P, Sanchez L, et al. The detection of B-cell monoclonal populations by polymerase chain reaction: accuracy of approach and application in gastric endoscopic biopsy specimens. Hum Pathol. 1993;24:1184-1188.
2. Auer IA, Gascoyne RD, Connors JM, et al. t(11:18)(q21:q21) is the most common translocation in MALT lymphomas. Ann Oncol. 1997;8:979-985.
3. Bayerdorffer E, Neubauer A, Rudolph B, et al. Regression of primary gastric lymphoma of mucosa associated lymphoid tissue type after cure of Helicobacter pylori infection. Lancet. 1995;345:1591-1594.
4. Bienenstock J, Befus AD. Mucosal immunology. Immunology. 1980;41:249-270.
5. Brynes RK, Almaguer PD, Leathery KE, et al. Numerical cytogenetic abnormalities of chromosomes 3, 7 and 12 in marginal zone B-cell lymphomas. Hum Pathol. 1996;9:995-1000.
6. Calvert RJ, Evans PAS, Randerson JA, et al. The significance of B-cell clonality in gastric lymphoid infiltrates. J Pathol. 1996;180:26-32.
7. Carlson SJ, Yokoo H, Vanagunas A. Progression of gastritis to monoclonal B-cell lymphoma with resolution and recurrence following eradication of Helicobacter pylori. JAMA. 1996;275:937-939.
8. Chan JKC, Ng CS, Isaacson PG. Relationship between high-grade lymphoma and low-grade B-cell mucosa associated lymphoid tissue lymphoma (MALToma) of the stomach. Am J Pathol. 1990;136:1153-1164.
9. Chong JM, Fukayama M, Hayashi Y, et al. Microsatellite instability and loss of heterozygosity in gastric lymphoma. Lab Invest. 1997;77:639-645.
10. Chott A, Vonderheid EC, Olbricht S, et al. The same dominant T cell clone is present in multiple regressing skin lesions and associated T cell lymphomas of patients with lymphomatoid papulosis. J Invest Dermatol. 1996;106:696-700.
11. Cogliatti SB, Schmid U, Schumacher U, et al. Primary B-cell gastric lymphoma: a clinicopathological study of 145 patients. Gastroenterology. 1991;101:1159-1170.
12. Collins RD. Is clonality equivalent to malignancy: specifically, is immunoglobulin gene rearrangement diagnostic of malignant lymphoma? Hum Pathol. 1997;28:757-759.
13. De Jong D, Boot H, Van Heerde P, et al. Histological grading and gastric lymphoma: pre-treatment criteria and clinical relevance. Gastroenterology. 1997;112:1466-1474.
14. de Mascarel A, Belleannee G, Vergier B, et al. Low incidence of monoclonal B-cells in 302 lymphoid gastritis associated with Helicobacter pylori. Mod Pathol. 1997;10:54A.
15. Dierlamm J, Pittaluga S, Wlodarska I, et al. Marginal zone B-cell lymphomas of different sites share similar cytogenetic and morphologic features. Blood. 1996;87:299-307.
16. Diss TC, Pan L, Peng H. Sources of DNA for detecting B cell monoclonality using PCR. J Clin Pathol. 1994;47:493-496.
17. Diss TC, Pan L. Polymerase chain reaction in the assessment of lymphomas. Cancer Surv. 1997;30:21-44.
18. Diss TC, Peng H, Wotherspoon AC, et al. Detection of monoclonality in low-grade B-cell lymphomas using the polymerase chain reaction is dependent on primer selection and lymphoma type. J Pathol. 1993;169:291-295.
19. Du M, Peng H, Singh N, et al. The accumulation of p53 abnormalities is associated with progression of mucosa-associated lymphoid tissue lymphoma. Blood. 1995;86:4587-4593.
20. Du MQ, Isaacson PG. Recent advances in our understanding of the biology and pathogenesis of gastric mucosa-associated lymphoid tissue (malt) lymphoma. Forum (Genova). 1998;8:162-173.
21. Fishleder A, Tubbs R, Hesse B, et al. Uniform detection of immunoglobulin-gene rearrangement in benign lymphoepithelial lesions. N Engl J Med. 1987;316:1118-1121.
22. Griffin CA, Zehnbauer BA, Beschorner WE, et al. t(11:18)(q21:q21) is a recurrent chromosome abnormality in small lymphocytic lymphoma. Genes Chromosomes Cancer. 1992;4:153-157.
23. His E, Siddiqui J, Alkan S. Analysis of immunoglobulin heavy chain gene rearrangement in myoepithelial sialadenitis by polymerase chain reaction. Mod Pathol. 1994;7:111A.
24. His ED, Greenson JK, Singleton TP, et al. Detection of immunoglobulin heavy chain gene rearrangement by polymerase chain reaction in chronic active gastritis associated with Helicobacter pylori. Hum Pathol. 1996;27:290-296.
25. Horsman D, Gascoyne R, Klasa. (t11:18)(q21:q21) A recurring translocation in lymphomas of mucosa-associated lymphoid tissue (MALT)? Genes Chromosomes Cancer. 1992;4:183-187.
26. Hussel T, Isaacson PG, Crabtree J, et al. In vitro studies of malignant B cells from low-grade B-cell gastric lymphoma of mucosa associated lymphoid tissue. In: Reiken EO, Zeitz M, Stallmach A, et al, eds. Malignancy and Chronic Inflammation of the Gastrointestinal Tract: New Concepts.[ Chapter 6]. Boston: Kluwer Academic, 1994.
27. Ionov Y, Peinado MA, Malkhosyan S, et al. Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis. Nature. 1993;363:558-561.
28. Isaacson P, Wright DH. Extranodal malignant lymphoma arising from mucosa associated lymphoid tissue. Cancer. 1984;53:2515-2524.
29. Isaacson P, Wright DH. Malignant lymphoma of mucosa-associated lymphoid tissue: a distinctive type of B-cell lymphoma. Cancer. 1983;52:1410-1416.
30. Isaacson PG, Norton AJ. Extranodal Lymphomas. London: Churchill Livingstone, 1994.
31. Isaacson PG, Spensor J. Malignant lymphoma of mucosa-associated lymphoid tissue. Histopathology. 1987;11:445-462.
32. Isaacson PG, Wotherspoon AC, Diss T, et al. Follicular colonization in B-cell lymphoma of mucosa-associated lymphoid tissue. Am J Surg Pathol. 1991;15:819-828.
33. Isaacson PG. Gastric MALT lymphoma: from concept to cure. Ann Oncol. 1999;10:637-645.
34. Jirieny J. Colon cancer and DNA repair: have mismatches met their match? Trends Genet. 1994;10:164-168.
35. Kopp P, Kimura ET, Aeschimann S, et al. Polyclonal and monoclonal thyroid nodules coexist within human multinodular goiters. J Clin Endocrinol Metab. 1994;79:134-139.
36. Leach FS, Nicolaides NC, Papadopoulos N, et al. Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer. Cell. 1993;75:1215-1225.
37. Leroux D, Seite P, Hillion J, et al. t(11:18)(q21:q21) may delineate a spectrum of diffuse small B-cell lymphoma with extranodal involvement. Genes Chromosomes Cancer. 1993;7:54-56.
38. Levine EG, Arthur DC, Machnicki J, et al. Four new recurring translocations in non-Hodgkin lymphoma. Blood. 1989;74:1796-1800.
39. Ludwig CU, Genick M, Shipman R. Multistep transformation in low-grade lymphoproliferative diseases. Ann Oncol. 1993;4:825-830.
40. Magrath IT. Concepts and controversies in lymphoid neoplasia. In: Magrath IT, ed. The Non-Hodgkin's Lymphomas, 2nd ed. London: Arnold, 1997:3-46.
41. Nakamura S, Aoyagi K, Furuse M, et al. B-cell monoclonality precedes the development of gastric MALT lymphoma in Helicobacter pylori-associated chronic gastritis. Am J Pathol. 1998;152:1271-1279.
42. Neubauer A, Thiede C, Morgner A, et al. Cure of Helicobacter pylori infection and duration of remission of low-grade gastric mucosa associated lymphoid tissue lymphoma. J Natl Cancer Inst. 1997;89:1350-1355.
43. Okazaki K, Morita M, Yamamoto Y. Gene rearrangements, Helicobacter pylori, and gastric MALT lymphoma. Lancet. 1994;343:1636.
44. Ou G, Katzenberger T, Greiner A, et al. The t(11:18)(q21:q21) chromosome translocation is a frequent and specific aberration in low-grade but not high-grade malignant non-Hodgkin's lymphomas of the mucosa-associated lymphoid tissue (MALT-type). Cancer Res. 1997;57:3944-3948.
45. Parsons R, Li GM, Longley MJ, et al. Hypermutability and mismatch repair deficiency in RER+ tumor cells. Cell. 1993;75:1227-1236.
46. Peng H, Chen G, Du M, et al. Replication error phenotype and p53 gene mutation in lymphomas of mucosa-associated lymphoid tissue. Am J Pathol. 1996;148:643-648.
47. Peng H, Diss T, Isaacson PG, et al. C-myc gene abnormalities in mucosa-associated lymphoid tissue (MALT) lymphomas. J Pathol. 1997;181:381-386.
48. Quintana PG, Kapadia SB, Bahler DW, et al. Salivary gland lymphoid infiltrates associated with lymphoepithelial lesions: a clinicopathologic, immunophenotypic and genotypic study. Hum Pathol. 1997;28:850-861.
49. Rhyu MG, Park WS, Meltzer SJ. Microsatellite instability occurs frequently in human gastric carcinoma. Oncogene. 1994;9:29-32.
50. Roggero E, Zucca E, Pinotti G, et al. Therapy outcome in primary low-grade gastric lymphoma of mucosa associated lymphoid tissue for H. pylori infection. Ann Intern Med. 1995;122:767-769.
51. Rudolph B, Bayerdorffer E, Ritter M, et al. Is the polymerase chain reaction or cure of Helicobacter pylori infection of help in the differential diagnosis of early gastric mucosa-associated lymphatic tissue lymphoma? J Clin Oncol. 1997;15:1104-1109.
52. Savio A, Franzin G, Wotherspoon AC, et al. Diagnosis and posttreatment follow-up of Helicobacter pylori-positive gastric lymphoma of mucosa-associated lymphoid tissue: histology, polymerase chain reaction, or both? Blood. 1996;87:1255-1260.
53. Saxena A, Moshynska O, Kanthan R, et al. Distinct B-cell clonal bands in Helicobacter pylori gastritis with lymphoid hyperplasia. J Pathol. 2000;190:47-54.
54. Segal GH, Jorgensen T, Masih AS, et al. Optimal primer selection for clonality assessment by polymerase chain reaction analysis: I. Low grade B-cell lymphoproliferative disorders of nonfollicular center cell type. Hum Pathol. 1994;25:1269-1275.
55. Simpson AJG. The natural somatic mutation frequency and human carcinogenesis. Adv Cancer Res. 1997;71:209-240.
56. Slack DN, McCathy KP, Wiedemann LM, et al. Evaluation of sensitivity, specificity, and reproducibility of an optimized method for detecting clonal rearrangements of immunoglobulin and T-cell receptor genes in formalin-fixed, paraffin embedded sections. Diagn Mol Pathol. 1993;2:223-232.
57. Soni M, Shabbab I, Fitzgerald M, et al. Detection of clonality in B-cell proliferations in Helicobacter pylori induced chronic gastritis in pediatric patients. Mod Pathol. 1997;10:65A.
58. Sorrentino D, Ferraccili G, DeVita S, et al. B-cell clonality and infection with Helicobacter pylori: implications for development of gastric lymphoma. Gut. 1996;38:837-840.
59. Spencer J, Finn T, Isaacson PG. Human Peyer's patches: an immunohistochemical study. Gut. 1986;27:405-410.
60. Spencer J, Finn T, Pulford KAF, et al. The human gut contains a noval population of B-lymphocytes which resemble marginal zone cells. Clin Exp Immunol. 1985;62:607-610.
61. Stolte M, Eidt S. Healing gastric MALT lymphomas by eradicating H. pylori? Lancet. 1993;342:568.
62. Stolte M. Helicobacter pylori gastritis and gastric MALT-lymphoma. Lancet. 1992;339:745-746.
63. Sukpanichnant S, Vnencak-Jones CL, McCurley TL. Determination of B-cell clonality in paraffin embedded endoscopic biopsy specimens of abnormal lymphocytic infiltrates and gastrointestinal lymphoma by polymerase chain reaction. Am J Clin Pathol. 1994;102:299-305.
64. Thiede C, Morgner A, Alpen B, et al. What role does Helicobacter pylori eradication play in gastric MALT and gastric MALT lymphoma? Gastroenterology. 1997;113:561-564.
65. Torlakovic E, Cherwitz DL, Jessurun J, et al. B-cell rearrangement in benign and malignant lymphoid proliferations of mucosa-associated lymphoid tissue and lymph nodes. Hum Pathol. 1997;28:166-173.
66. Villuendas R, Piris MA, Orradre JL, et al. Different bcl-2 protein expression in high-grade B-cell lymphomas derived from lymph node or mucosa-associated lymphoid tissue. Am J Pathol. 1991;139:989-993.
67. Weber DM, Dimopoulos MA, Anandu DP, et al. Regression of gastric lymphoma of mucosa-associated lymphoid tissue with antibiotic therapy for Helicobacter pylori. Gastroentemlogy. 1994;107:1835-1838.
68. Willis TG, Jaydyel DM, Du MQ, et al. Bcl-10 is involved in t(1:14)(p22: q32) of MALT B-cell lymphoma and mutated in multiple tumor types. Cell. 1999;96:35-45.
69. Wotherspoon AC, Doglioni C, de Boni M, et al. Antibiotic treatment for low-grade gastric MALT lymphoma. Lancet. 1994;343:1503.
70. Wotherspoon AC, Doglioni C, Diss TC, et al. Regression of primary low-grade B-cell gastric lymphoma of mucosa-associated lymphoid tissue type after eradication of Helicobacter pylori. Lancet. 1993;342:575-577.
71. Wotherspoon AC, Finn TM, Isaacson PG. Trisomy 3 in low-grade B-cell lymphomas of mucosa-associated lymphoid tissue. Blood. 1995;85:2000-2004.
72. Wotherspoon AC, Pan LX, Diss TC, et al. Cytogenetic study of B-cell lymphoma of mucosa-associated lymphoid tissue. Cancer Genet Cytogenet. 1992;58:35-38.
73. Xu WS, Chan ACL, Liang R, et al. No evidence of replication error phenotype in primary gastric lymphoma of mucosa-associated lymphoid tissue. Int J Cancer. 1998;76:635-638.
74. Zucca E, Bertoni F, Roggero E, et al. Molecular analysis of the progression from Helicobacter pylori-associated chronic gastritis to mucosa-associated lymphoid-tissue lymphoma of the stomach. N Engl J Med. 1998;338:804-810.