Population pharmacokinetics of recombinant factor XIII in cynomolgus monkeys

AAPS Journal

Volumn 7, Issue 3, 2005, Pages

  Dodds, Michael G ^a,b   Visich, Jennifer E ^b   Vicini, Paolo ^a  

^a University of Washington   (United States)

^b ZYMOGENETICS INC   (United States)

Author keywords

FXIII; Modeling; Pharmacokinetics; Population kinetics

Indexed keywords

BLOOD CLOTTING FACTOR 13A; BLOOD CLOTTING FACTOR 13B; BLOOD CLOTTING FACTOR 8; F8 PROTEIN, HUMAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD CLOTTING FACTOR 13 DEFICIENCY; BLOOD SAMPLING; COMPLEX FORMATION; CONTROLLED STUDY; CROSS LINKING; DRUG BLOOD LEVEL; DRUG DOSE REGIMEN; DRUG HALF LIFE; ENZYME LINKED IMMUNOSORBENT ASSAY; FIBRINOLYSIS; MACACA; NONHUMAN; POPULATION DYNAMICS; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE; STOICHIOMETRY; ANIMAL; BIOLOGICAL MODEL; COMPARATIVE STUDY; DOSE RESPONSE; PHARMACOKINETICS; TISSUE DISTRIBUTION;

ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; FACTOR VIII; MACACA FASCICULARIS; MODELS, BIOLOGICAL; PHARMACOKINETICS; TISSUE DISTRIBUTION;

EID: 33644789435     PISSN: 15221059     EISSN: 15221059     Source Type: Journal    
DOI: 10.1208/aapsj070370     Document Type: Article

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