QSAR for anti-malarial activity of 2-aziridinyl and 2,3-bis(aziridinyl)-1,4-naphthoquinonyl sulfonate and acylate derivatives

Journal of Molecular Modeling

Volumn 12, Issue 4, 2006, Pages 398-405

  Zahouily, Mohamed ^a   Lazar, Mohamed ^a   Elmakssoudi, Abdelhakim ^a   Rakik, Jamila ^a   Elaychi, Sanaa ^a   Rayadh, A ^a  

^a HASSAN II UNIVERSITY   (Morocco)

Author keywords

2D QSAR; ANN; Anti malarial activity; MLR; Pertinent descriptors

Indexed keywords

2 AZIRIDINYL 1,4 NAPHTHOQUINONYLACYLIC ACID DERIVATIVE; 2 AZIRIDINYL 1,4 NAPHTHOQUINONYLSULFONIC ACID DERIVATIVE; 2,3 BIS(AZIRIDINYL) 1,4 NAPHTHOQUINONYLACYLIC ACID DERIVATIVE; 2,3 BIS(AZIRIDINYL) 1,4 NAPHTHOQUINONYLSULFONIC ACID DERIVATIVE; ANTIMALARIAL AGENT; UNCLASSIFIED DRUG;

ANTIMALARIAL ACTIVITY; ARTICLE; ARTIFICIAL NEURAL NETWORK; BIOLOGICAL MODEL; CORRELATION COEFFICIENT; DRUG STRUCTURE; HYDROGEN BOND; HYDROPHOBICITY; IC 50; MOLECULAR WEIGHT; MULTIPLE LINEAR REGRESSION ANALYSIS; PRIORITY JOURNAL; QUANTITATIVE STRUCTURE ACTIVITY RELATION; VALIDATION PROCESS;

EID: 33644782970     PISSN: 16102940     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00894-005-0059-x     Document Type: Article

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