Adhesion molecule CD44 expression in non-tumor epithelium adjacent to laryngeal cancer

Onkologie

Volumn 29, Issue 1-2, 2006, Pages 9-13

  González Moles, Miguel Angel ^a,d   Esteban, Francisco ^b   Bravo Pérez, Jose Javier ^a   Bravo Perez, Manuel ^a   Ruiz Ávila, Isabel ^c   Gil Montoya, José Antonio ^a   González Moles, Salvador ^a  

^a UNIVERSITY OF GRANADA   (Spain)

^b HOSPITAL UNIVERSITARIO VIRGEN DEL ROCÍO   (Spain)

^c Jaen General Hospital   (Spain)

^d Campus Cartuja   (Spain)

Author keywords

Adhesion molecule; CD44; Immunohistochemistry; Laryngeal carcinoma; Non tumor epithelium, adjacent

Indexed keywords

CELL ADHESION MOLECULE; HERMES ANTIGEN; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY CD44; UNCLASSIFIED DRUG;

ADULT; AGED; ANTIGEN EXPRESSION; ARTICLE; CANCER TISSUE; CARCINOGENESIS; CONTROLLED STUDY; DISEASE ASSOCIATION; EPITHELIUM; EPITHELIUM DYSPLASIA; EPITHELIUM HYPERPLASIA; HISTOLOGY; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LARYNX CANCER; MAJOR CLINICAL STUDY; MALE;

ADULT; AGED; AGED, 80 AND OVER; ANTIGENS, CD44; CARCINOMA, SQUAMOUS CELL; CELL ADHESION MOLECULES; DOWN-REGULATION; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LARYNGEAL MUCOSA; LARYNGEAL NEOPLASMS; MALE; MIDDLE AGED; NEOPLASM PROTEINS; TISSUE DISTRIBUTION; TUMOR MARKERS, BIOLOGICAL;

EID: 33644772527     PISSN: 0378584X     EISSN: None     Source Type: Journal    
DOI: 10.1159/000089801     Document Type: Article

References (22)

1. Califano J, van der Riet P, Westra W, Nawroz H, Clayman G, Piantadosi S, Corio R, Lee D, Greenberg B, Koch W, Sidransky D: Genetic progression model for head and neck cancer: implications for field cancerization. Cancer Res 1996;56:2488-2492.
2. González-Moles MA, Galindo P, Gutiérrez J, Rodríguez-Archilla A, Ruiz-Ávila I, Sánchez- Fernández E: Significance of p53 expression in non-tumoral epithelium adjacent to oral squamous cell carcinomas. J Laryngol Otol 2002;116:355-358.
3. Warnakulasuriya KA, Johnson NW: Expression of p53 mutant nuclear phosphoprotein in oral carcinoma and potentially malignant oral lesions. J Oral Pathol Med;1992;21:404-408.
4. Shin DM, Kim J, Ro JY, Hittelman J, Roth JA, Hong WK, Hittelman WN: Activation of p53 gene expression in premalignant lesions during head and neck tumorigenesis. Cancer Res 1994;54:321-326.
5. Lavieille JP, Brambilla E, Riva-Lavieille C, Reyt E, Charachon R, Brambilla C: Immunohistochemical detection of p53 protein in preneoplastic lesions and squamous cell carcinoma of the head and neck. Acta Otolaryngol 1995;115:334-339.
6. Regezi JA, Zarbo RJ, Regev E, Pisanty S, Silverman S, Gazit D: p53 protein expression in sequential biopsies of oral dysplasias and in situ carcinomas. J Oral Pathol Med 1995;24:18-22.
7. González-Moles MA, Ruiz-Ávila I, Rodríguez-Archilla A, Martínez-Lara I: Suprabasal expression of Ki-67 antigen as a marker of oral epithelial dysplasia. Head Neck 2000;22:658-661.
8. Hirvikoski P, Tammi R, Kumpulainen E, Virtaniemi J, Parkkinen JJ, Tammi M, Johansson R, Agren U, Karhunen J, Kosma VM: Irregular expression of hyaluronan and its CD44 receptor is associated with metastatic phenotype in laryngeal squamous cell carcinoma. Virchows Arch 1999;434:37-44.
9. Ioachim E, Assimakopoulos D, Goussia AC, Peschos D, Skevas A, Agnantis NJ: Glycoprotein CD44 expression in benign, premalignant and malignant epithelial lesions of the larynx: an immunohistochemical study including correlation with Rb, p53, Ki-67 and PCNA. Histol Histopathol 1999;14: 1113-1118.
10. Esteban F, Bravo JJ, Gonzalez-Moles MA, Bravo M, Ruiz-Avila I, Gil-Montoya JA: Adhesion molecule CD44 as a prognostic factor in laryngeal cancer. Anticancer Res 2005;25:1115-1121.
11. González-Moles MA, Bravo M, Ruiz-Avila I, Esteban F, Bascones-Martinez A, González-Moles S: Adhesion molecule CD44 expression in non-tumour epithelium adjacent to tongue cancer. Oral Oncol 2004;40:281-286.
12. Spiessl B: International Union against Cancer. TNM Atlas Illustrated Guide to the TNM, pTNM Classification of Malignant Tumors. ed 3, rev 2. Berlin, Springer, 1992.
13. González-Moles MA, Esteban F, Rodríguez-Archilla A, Ruiz-Ávila I, González-Moles S: Importance of tumour thickness measurement in prognosis of tongue cancer. Oral Oncol 2002;38: 394-397.
14. Stoll C, Baretton G, Soost F, Terpe HJ, Domide P, Lohrs U: Prognostic importance of the expression of CD44 splice variants in oral squamous cell carcinomas. Oral Oncol 1999;35:484-489.
15. Kanke M, Fujii M, Kameyama K, Kanzaki J, Tokumaru Y, Imanishi Y, Tomita T, Matsumura Y.: Role of CD44 variant exon 6 in invasion of head and neck squamous cell carcinoma. Arch Otolaryngol Head Neck Surg 2000;126:1217-1223.
16. Fonseca I, Pereira T, Rosa-Santos J, Soares J: Expression of CD44 isoforms in squamous cell carcinoma of the border of the tongue: A correlation with histological grade, pattern of stromal invasion, and cell differentiation. J Surg Oncol 2001;76: 115-120.
17. Sato S, Miyauchi M, Takekoshi T, Zhao M, Kudo Y, Ogawa I, Kitagawa S, Fujita M, Takata T: Reduced expression of CD44 variant 9 is related to lymph node metastasis and poor survival in squamous cell carcinoma of tongue. Oral Oncol 2000; 36:545-549.
18. Hudson DL, Sleeman J, Watt FM: CD44 is the major peanut lectin-binding glycoprotein of human epidermal keratinocytes and plays a role in intercellular adhesion. J Cell Sci 1995;108: 1959-1970.
19. Soukka T, Salmi M, Joensuu H, Hakkinen L, Sointu P, Koulu L, Kalimo K, Klemi P, Grenman R, Jalkanen S: Regulation of CD44v6-containing isoforms during proliferation of normal and malignant epithelial cells. Cancer Res 1997;57:2281-2289.
20. Bahar R, Kunishi M, Kayada Y, Yoshiga K: CD44 variant 6 (CD44v6) expression as a progression marker in benign, premalignant and malignant oral epithelial tissues. Int J Oral Maxillofac Surg 1997;26:443-446.
21. Kuo MY, Cheng SJ, Chen HM, Kok SH, Hahn LJ, Chiang CP: Expression of CD44s, CD44v5, CD44v6 and CD44v7-8 in betel-quid-chewing-associated oral premalignant cell carcinomas in Taiwan. J Oral Pathol Med 1998;27:428-433.
22. Rautava J, Soukka T, Inki P, Leimola-Virtanen R, Saloniemi I, Happonen RP, Heikinheimo K: CD44v6 in developing, dysplastic and malignant oral epithelia. Oral Oncol 2003;39:373-379.