Purification of monoclonal antibodies from cell culture supernatants by Gradiflow™ electrophoresis technology

Journal of Chemical Technology and Biotechnology

Volumn 81, Issue 3, 2006, Pages 445-453

  Mahler, Stephen M ^a   Leong, Sharon ^b   Gilbert, Andrew ^a,b   Yang, Fan ^a   Gray, Peter ^a   Van Dyk, Derek ^a   Roeth, Philip ^b  

^a UNIVERSITY OF NEW SOUTH WALES   (Australia)

^b Life Therapeutics   (Australia)

Author keywords

Antibody purification; Monoclonal antibodies; Preparative electrophoresis

Indexed keywords

AFFINITY CHROMATOGRAPHY; CELL CULTURE; ELECTROPHORESIS; FILTRATION; ION EXCHANGE; MONOCLONAL ANTIBODIES; PROTEINS;

ANTIBODY PURIFICATION; DOWNSTREAM PROCESSING; GEL FILTRATION; PREPARATIVE ELECTROPHORESIS; PURITY; SUPERNATANTS;

PURIFICATION;

CHIMERIC ANTIBODY; IMMUNOGLOBULIN G1 ANTIBODY; MONOCLONAL ANTIBODY;

AFFINITY CHROMATOGRAPHY; CELL CULTURE; ELECTROPHORESIS; FILTRATION; ION EXCHANGE; MONOCLONAL ANTIBODIES; PROTEINS; PURIFICATION;

AFFINITY CHROMATOGRAPHY; ANALYTIC METHOD; ANTIBODY ENGINEERING; ANTIBODY PRODUCTION; ARTICLE; BIOMEDICAL TECHNOLOGY ASSESSMENT; BIOTECHNOLOGY; CHO CELL; DIAGNOSTIC TEST; DOWNSTREAM PROCESSING; HUMAN; HYBRIDOMA CELL CULTURE; INTERMETHOD COMPARISON; MOUSE; NONHUMAN; PROTEIN ELECTROPHORESIS; PROTEIN PURIFICATION; SUPERNATANT;

CRICETULUS GRISEUS; MURINAE;

EID: 33644752104     PISSN: 02682575     EISSN: 10974660     Source Type: Journal    
DOI: 10.1002/jctb.1426     Document Type: Article

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