Amphenicol and macrolide derived antibiotics inhibit paraoxonase enzyme activity in human serum and human hepatoma cells (HepG2) in vitro

Biochemistry (Moscow)

Volumn 71, Issue 1, 2006, Pages 46-50

  Sinan, S ^a   Kockar, F ^a   Gencer, N ^a   Yildirim, H ^a   Arslan, O ^a  

^a BALIKESIR UNIVERSITY   (Turkey)

Author keywords

Chloramphenicol; Clarithromycin; HepG2; In vitro; Inhibition; Paraoxonase

Indexed keywords

AMMONIUM COMPOUNDS; ANTIBIOTICS; CELLS; HYDROPHOBIC CHROMATOGRAPHY; PRECIPITATION (CHEMICAL); PURIFICATION;

CHLORAMPHENICOL; HEPG2; IN VITRO; PARAOXONASE;

ENZYMES;

ANTIINFECTIVE AGENT; ARYLDIALKYLPHOSPHATASE; CHLORAMPHENICOL; CLARITHROMYCIN; ENZYME INHIBITOR; MACROLIDE;

ARTICLE; BLOOD; CHEMISTRY; DRUG ANTAGONISM; HUMAN; IC 50; ISOLATION AND PURIFICATION; METABOLISM; TUMOR CELL LINE;

ANTI-BACTERIAL AGENTS; ARYLDIALKYLPHOSPHATASE; CELL LINE, TUMOR; CHLORAMPHENICOL; CLARITHROMYCIN; ENZYME INHIBITORS; HUMANS; INHIBITORY CONCENTRATION 50; MACROLIDES;

EID: 33644689513     PISSN: 00062979     EISSN: 16083040     Source Type: Journal    
DOI: 10.1134/S0006297906010068     Document Type: Article

References (43)

1. Mackness, M. I., Thompson, H. M., Hardy, A. R., and Walker, C. H. (1987) Biochem. J., 245, 293-296.
2. La Du, B. N., Adkins, S., and Bayoumi, R. A. (1986) Progr. Clin. Biol. Res., 214, 87-98.
3. Gan, K. N., Smolen, A., Eckerson, H. W., and La Du, B. N. (1991) Drug Metab. Dispos., 19, 100-106.
4. Primo-Parmo, S. L., Sorenson, R. S., Teiber, J., and La Du, B. N. (1996) Genomics, 33, 498-507.
5. Reiner, E., Aldridge, W. N., and Hoskin, F. C. G. (1989) Enzymes Hydrolyzing Organophosphorus Compounds, John Wiley & Sons, Inc, New York.
6. Baillie, T. A., Moldeus, P., Mason, R. P., and Younes, M. (1993) Enzymes Interacting with Organophosphorus Compounds, Elsevier Scientific Publishers Ireland Ltd, Shannon.
7. Davies, H. G., Richter, R. J., Keifer, M., Broomfield, C. A., Sowalla, J., and Furlong, C. E. (1996) Nat. Genet., 14, 334-336.
8. Aldridge, W. N. (1953) Biochem. J., 53, 117-124.
9. La Du, B. N. (1992) in Pharmacogenetics of Drug Metabolism (Kalow, W., ed.) Pergamon Press, New York, pp. 51-91.
10. Miller, G. J., and Miller, N. E. (1975) Lancet, 4, 16-19.
11. Parthasarathy, S., Barnett, J., and Fong, L. G. (1990) Biochim. Biophys. Acta, 1044, 275-283.
12. Ohta, T., Takata, S., and Morino, Y. (1989) FEBS Lett., 257, 435-438.
13. Mackness, M. I., Abbott, C. A., and Arrol, S. (1993) Biochem. J., 294, 829-835.
14. Steinberg, D., Parthasarathy, S., and Carew, T. E. (1989) N. Engl. J. Med., 320, 915-924.
15. Mackness, M. I., and Durrington, P. N. (1995) Atherosclerosis, 115, 243-253.
16. Mackness, M. I., Arrol, S., and Durrington, P. N. (1991) FEBS Lett., 286, 152-154.
17. Shih, D. M., Gu, I., and Xia, Y.-R. (1998) Nature, 394, 284-287.
18. Aviram, M., Hardak, E., and Vaya, J. (2000) Circulation, 101, 2510-2517.
19. Gouedard, C., Koum-Besson, N., Barouki, R., and Morel, Y. (2003) Mol. Pharmacol., 63, 945-956.
20. Aviram, M., Rosenblat, M., Bisgaier, C. L., and Newton, R. S. (1998) Atherosclerosis, 138, 271-280.
21. Beltowski, J., Wojcicka, G., and Jamroz, A. (2004) J. Cardiovasc. Pharmacol., 43, 121-127.
22. Deakin, S., Leviev, I., Guernier, S., and James, R. W. (2003) Arterioscler. Thromb. Vasc. Biol., 23, 2083-2091.
23. Jarvik, G. P., Trevanian, Tsai, N., McKinstry, L. A., Wani, R., Brophy, V. H., and Richter, C. (2002) Arterioscler. Thromb. Vasc. Biol., 22, 1329-1333.
24. Balogh, Z., Seres, I., Marangi, M., Kovacs, P., Kakuk, G., and Paragh, G. (2001) Diabetes Metab., 27, 604-610.
25. Paragh, G., Seres, I., Harangi, M., Balogh, Z., Illyes, L., and Boda, J. (2003) Diabetes Metab., 29, 613-618.
26. Turay, J., Grniakova, V., and Valka, J. (2000) J. Drugs Exp. Clin. Res., 26, 83-91.
27. Durringhton, P. N., Mackness, M. I., Bhatnagar, D., Julier, K., Prais, H., and Arrol, S. (1998) Atherosclerosis, 138, 217-242.
28. Radic, Z., and Reiner, E. (1986) Acta Pharm. Jugosl., 36, 1-7.
29. Blatter-Garin, M. C., Kalix, B., De Pre, S., and James, R. W. (2003) Diabetologia, 46, 593-597.
30. All, B., Zhang, Q., Lim, Y. K., Feng, D., Retnam, L., and Lim, S. K. (2003) Free Rad. Biol. Med., 34, 824-833.
31. Rodrigues, A. D., Roberts, E. M., Mulford, D. J., Yao, Y., and Quellet, D. (1997) Drug Metab. Dispos., 25, 623-630.
32. Bruce, M. A., Hall, S. D., Haehner-Daniels, B. D., and Gorski, J. C. (2001) Drug Metab. Dispos., 29, 1023-1028.
33. Best, W. (1998) Enzymes. Their Modes of Action and Inhibition, Biological Chemistry by Wayne Best-Lecture 3.
34. Bradford, M. M. (1976) Analyt. Biochem., 72, 248-251.
35. Sinan, S., Arslan, O., Kockar, F., Gencer, N., and Bozkurt, H. (2004) I Int. Conf. "Paraoxonases - Basic and Clinical Directions of Current Research", 22-24 April, Michigan Union, University of Michigan, Ann Arbor, USA.
36. Laemmli, U. K. (1970) Nature, 111, 680.
37. Foka, P., Irvine, S., Kockar, F., and Ramji, D. P. (2003) Nucleic Acids Res., 31, 1-11.
38. Rodrigo, L., Gil, F., Hernandez, A. F., Marina, A., Vazquez, J., and Pla, A. (1997) Biochem. J., 321, 595-601.
39. Rodrigo, L., Gil, F., Hernandez, F. A., Lopez, O., and Pla, A. (2003) Biochem. J., 376, 261-268.
40. Furlong, C. E., Costa, L. G., Hasett, C., Richter, R. J., Sundstrom, J. A., Adler, D. A., Disteche, C. M., Omiecinski, C. J., Crabb, J. W., and Humbert, R. (1993) Chem.-Biol. Interact., 87, 35-48.
41. Reiner, E., Aldridge, W. N., and Hoskin, F. C. G. (1989) Enzymes Hydrolyzing Organophosphorus Compounds, John Wiley & Sons, Inc, New York.
42. Gonzalvo, M. C., Gil, F., Hernandez, A. F., Villanueva, E., and Pla, A. (1997) Chem. Biol. Interact., 105, 169-179.
43. Gorski, J. C., Jones, D. R., Haehner-Daniels, B. D., Hamman, M. A., O'Mara, E. M., Jr., and Hall, S. D. (1998) Clin. Pharmacol. Ther., 64, 133.