Plasma gastrin measurement cannot be used to diagnose a gastrinoma in patients on either proton pump inhibitors or histamine type-2 receptor antagonists

Annals of Clinical Biochemistry

Volumn 43, Issue 2, 2006, Pages 153-155

  Dhillo, W S ^a   Jayasena, C N ^a   Lewis, C J ^a   Martin, N M ^a   Tang, K C N ^a   Meeran, K ^a   Todd, J F ^a  

^a HAMMERSMITH HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GASTRIN; HISTAMINE H2 RECEPTOR ANTAGONIST; PROTON PUMP INHIBITOR;

ADULT; AGED; ARTICLE; BLOOD ANALYSIS; BLOOD SAMPLING; CONTROLLED STUDY; DIAGNOSTIC TEST; DIAGNOSTIC VALUE; DIET RESTRICTION; GASTRIN BLOOD LEVEL; GASTRINOMA; HUMAN; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; STATISTICAL SIGNIFICANCE; TREATMENT WITHDRAWAL;

AGED; FEMALE; GASTRINOMA; GASTRINS; HISTAMINE H2 ANTAGONISTS; HUMANS; MALE; MIDDLE AGED; PANCREATIC NEOPLASMS; PROTON PUMPS;

EID: 33644679953     PISSN: 00045632     EISSN: 00045632     Source Type: Journal    
DOI: 10.1258/000456306776021607     Document Type: Article

References (5)

1. Jensen RT. Gastrinomas: advances in diagnosis and management. Neuroendocrinology 2004; 80(Suppl. 1): 23-7
2. Cadiot G, Vissuzaine C, Pospai D, Ruszniewski P, Potet F, Mignon M. Effect of prolonged treatment with proton pump inhibitors on serum gastrin levels and the fundus mucosa. Preliminary results. Gastroenterol Clin Biol 1995; 19: 811-7
3. Ashrafian H, Taylor-Robinson SD, Calam J, Playford RJ. Once you start, you can't stop. Lancet 2002; 359: 226
4. Arroyo Villarino MT, Lanas AA, Esteva DF, Ortego Fernandez de RJ, Sainz SR. Effects of long-term treatment with lansoprazole and omeprazole on serum gastrin and the fundic mucosa. Rev Esp Enferm Dig 1997; 89: 347-56
5. Russel RC, Bloom SR, Fielding LP, Bryant MG. Current problems in the measurement of gastrin release. A reproducible measure of physiological gastrin release. Postgrad Med J 1976; 52: 645-50