Chemical peeling by SA-PEG remodels photo-damaged skin: Suppressing p53 expression and normalizing keratinocyte differentiation

Journal of Investigative Dermatology

Volumn 126, Issue 2, 2006, Pages 416-421

  Dainichi, Teruki ^a   Amano, Satoshi ^b   Matsunaga, Yukiko ^b   Iriyama, Shunsuke ^b   Hirao, Tetsuji ^b   Hariya, Takeshi ^b   Hibino, Toshihiko ^b   Katagiri, Chika ^b   Takahashi, Motoji ^b   Ueda, Setsuko ^c   Furue, Masutaka ^a  

^a KYUSHU UNIVERSITY   (Japan)

^b SHISEIDO RESEARCH CENTER   (Japan)

^c Ueda Setsuko Clinic   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

FILAGGRIN; LORICRIN; MACROGOL; PROTEIN P53; SALICYLIC ACID;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER PREVENTION; CARCINOGENESIS; CELL DIFFERENTIATION; COMPARATIVE STUDY; CONTROLLED STUDY; EXPOSURE; FACE; FEMALE; HUMAN; HUMAN EXPERIMENT; KERATINOCYTE; LIGHT DAMAGE; MALE; MOUSE; NONHUMAN; NUDE MOUSE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SKIN DEFECT; SKIN TUMOR; STRATUM CORNEUM; ULTRAVIOLET B RADIATION;

ANIMALS; ANTICARCINOGENIC AGENTS; CELL DIFFERENTIATION; FEMALE; HUMANS; INTERMEDIATE FILAMENT PROTEINS; KERATINOCYTES; MALE; MEMBRANE PROTEINS; MICE; MICE, INBRED HRS; NEOPLASMS, RADIATION-INDUCED; POLYETHYLENE GLYCOLS; RADIATION-PROTECTIVE AGENTS; SALICYLIC ACIDS; SKIN; SKIN AGING; TUMOR SUPPRESSOR PROTEIN P53; ULTRAVIOLET RAYS;

EID: 33644650819     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/sj.jid.5700066     Document Type: Article

References (32)

1. Berg RJW, Van Kranen HF, Rebel HG et al. (1996) Early p53 alterations in mouse skin carcinogenesis by UVB radiation: immunohistochemical detection of mutant p53 protein in clusters of preneoplastic epidermal cells. Proc Natl Acad Sci USA 93:274-8
2. Brody HJ, Hailey CW (1986) Medium-depth chemical peeling of the skin: a variation of superficial chemosurgery. J Dermatol Surg Oncol 12:1268-75
3. Cabral A, Sayin A, De Winter S, Fischer DF, Pavel S, Backendorf C (2001) SPRR4, a novel cornified envelope precursor: UV-dependent epidermal expression and selective incorporation into fragile envelopes. J Cell Sci 114:3837-43
4. Chernov MV, Stark GR (1997) The p53 activation and apoptosis induced by DNA damage are reversibly inhibited by salicylate. Oncogene 14:2503-10
5. Dainichi T, Ueda S, Isoda M, Koga T, Kinukawa N, Nose Y et al. (2003) Chemical peeling with salicylic acid in polyethylene glycol vehicle suppresses skin tumour development in hairless mice. Br J Dermatol 148:906-12
6. de Gruijl FR (2002) p53 mutations as a marker of skin cancer risk: comparison of UVA and UVB effects. Exp Dermatol 11(Suppl 1):37-9
7. de Gruijl FR, Sterenborg HJCM, Forbes PD, Davies RE, Cole C, Kelfkens G et al. (1993) Wavelength dependence of skin cancer induction by ultraviolet irradiation of albino hairless mice. Cancer Res 53:53-60
8. Fears TR, Scotto J, Schneiderman MA (1977) Mathematical models of age and ultraviolet effects on the incidence of skin cancer among Whites in the United States. Am J Epidemiol 105:420-7
9. Forbes PD, Davies RE, Urbach F, Berger D, Cole C (1982) Simulated stratospheric ozone depletion and increased ultraviolet radiation: effects on photocarcinogenesis in hairless mice. Cancer Res 42:2796-803
10. Green AE, Hedinger RA (1978) Models relating ultraviolet light and non-melanoma skin cancer incidence. Photochem Photobiol 28:283-91
11. Hirao T, Denda M, Takahashi M (2001) Identification of immature cornified envelopes in the barrier-impaired epidermis by characterization of their hydrophobicity and antigenicities of the components. Exp Dermatol 10:35-44
12. Hohl D (1990) Cornified cell envelope. Dermatologica 180:201-11
13. Hong JT, Kim EJ, Ahn KS, Jung KM, Yun YP, Park YK et al. (2001) Inhibitory effect of glycolic acid on ultraviolet-induced skin tumorigenesis in SKH-1 hairless mice and its mechanism of action. Mol Carcinogen 31:152-60
14. Imayama S, Ueda S, Isoda M (2000) Histologic changes in the skin of hairless mice following peeling with salicylic acid. Arch Dermatol 136:1390-5
15. Inomata S, Matsunaga Y, Amano S, Takeda K, Kobayashi K, Tsunenaga M et al. (2003) Possible involvement of gelatinases in basement membrane damage and wrinkle formation in chronically ultraviolet B-exposed hairless mouse. J Invest Dermatol 120:128-34
16. Ishida-Yamamoto A, Iizuka H (1988) Structural organization of cornified cell envelopes and alterations in inherited skin disorders. Exp Dermatol 7:1-10
17. Isoda M, Ueda S, Imayama S, Tsukahara K (2001) New formulation of chemical peeling agent: histological evaluation in sun-damaged skin model in hairless mice. J Dermatol Sci 27(Suppl 1):S60-7
18. Jansen B, Heere-Ress E, Schlagbauer-Wadl H, Halaschek-Wiener J, Waltering S, Moll I et al. (1999) Farnesylthiosalicylic acid inhibits the growth of human Merkel cell carcinoma in SCID mice. J Mol Med 77:792-7
19. Jonason AS, Kunala S, Price GJ, Restifo RJ, Spinelli HM, Persing JA et al. (1996) Frequent clones of p53-mutated keratinocytes in normal human skin. Proc Natl Acad Sci USA 93:14025-9
20. Kligman D, Kligman AM (1998) Salicylic acid peels for the treatment of photoaging. Dermatol Surg 24:325-8
21. Kligman LH (1989) The ultraviolet-irradiated hairless mouse: a model for photoaging. J Am Acad Dermatol 21:623-31
22. Leffel DJ (2000) The scientific basis of skin cancer. J Am Acad Dermatol 42:S18-22
23. Madison KC (2003) Barrier function of the skin: "la raison d'être" of the epidermis. J Invest Dermatol 121:231-41
24. McGregor JM, Yu CC, Dublin EA, Levison DA, MacDonald DM (1992) Aberrant expression of p53 tumour-suppressor protein in non-melanoma skin cancer. Br J Dermatol 127:463-9
25. Meguro S, Arai Y, Masukawa Y, Uie K, Tokimitsu I (2000) Relationship between covalently bound ceramides and transepidermal water loss (TEWL). Arch Dermatol Res 292:463-8
26. Michel S, Schmidt R, Shroot B, Reichert U (1988) Morphological and biochemical characterization of the cornified envelopes from human epidermal keratinocytes of different origin. J Invest Dermatol 91:11-5
27. Nemes Z, Steinert PM (1999) Bricks and mortar of the epidermal barrier. Exp Mol Med 31:5-19
28. Proksch E, Holleran WM, Menon GK, Elias PM, Feingold KR (1993) Barrier function regulates epidermal lipid and DNA synthesis. Br J Dermatol 128:473-82
29. Scotto J, Fears TR (1983) Estimating increases in skin cancer morbidity due to increases in ultraviolet radiation exposure. Cancer Invest 1:119-26
30. Takagi Y, Nakagawa H, Kondo H, Takema Y, Imokawa G (2004) Decreased levels of covalently bound ceramide are associated with ultraviolet B-induced perturbation of the skin barrier. J Invest Dermatol 123:1102-9
31. Ueda S, Mitsugi K, Ichige K, Yoshida K, Sakuma T, Ninomiya S et al. (2002) New formulation of chemical peeling agent: 30% salicylic acid in polyethylene glycol. Absorption and distribution of 14C-salicylic acid in polyethylene glycol applied topically to skin of hairless mice. J Dermatol Sci 28:211-8
32. Watt FM, Jordan PW, O'Neill CH (1988) Cell shape controls terminal differentiation of human epidermal keratinocytes. Proc Natl Acad Sci USA 85:5576-80