Chiral separation of ibuprofen by supercritical fluid chromatography

Chinese Journal of Chemical Engineering

Volumn 13, Issue 6, 2005, Pages 741-746

  Han, Soonkoo ^a   Row, Kyungho ^a  

^a Inha University   (South Korea)

Author keywords

Chiral separation; Ibuprofen; Resolution; Retention factor; Supercritical fluid chromatography

Indexed keywords

CARBON DIOXIDE; CHROMATOGRAPHIC ANALYSIS; LIQUID CHROMATOGRAPHY; MEDICINE; MIXTURES; SUPERCRITICAL FLUIDS;

CHIRAL SEPARATION; IBUPROFEN; RESOLUTION; RETENTION FACTOR; SUPERCRITICAL FLUID CHROMATOGRAPHY;

SEPARATION;

EID: 33644649219     PISSN: 10049541     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (22)

1. Ahuja, S., Chiral Separation by Chromatography, Oxford Univ. Press, New York (2000).
2. Medvedovici, A., Sandra, P., Torbio, L., David, F., Module performance of anion-exchange porous hollow-fiber membranes for high-speed protein recovery, J. Chromatogr. A., 785, 159-171 (1997).
3. Manon, S.V., Robert, A.J., Analytical supercritical fluid chromatography using fully automated column and modifier selection valves for the rapid development of chiral separations, J. Chromatogr. A., 826, 217-225 (1998).
4. Choi, Y.J., Han, S.K., Jung S.T., Row, K.H., Chromatographic separation of bupivacaine recemate by mathematical model with competitive Langmuir isotherm, Korean J. Ch. Eng., 21, 829-835 (2004).
5. Maier, N.M., Franco, P., Lindner, W., Separation of enantiomers: needs, challenges, perspectives, J. Chromatogr. A., 906, 3-33 (2001).
6. Perrin, C., Vu, V.A., Matthijs, N., Maftouh, M., Massart, D.L., Heyden, Y.V., Screening approach for chiral separation of pharmaceuticals: Part I. Normal-phase liquid chromatography, J. Chromatogr. A., 947, 69-83 (2002).
7. Klesper, E., Corwin, A.H., Turner, D.A., High pressure gas chromatography above critical temperatures, J. Org. Chem., 27, 700-701 (1962).
8. Liu, Y., Berthod, A., Mitchell, C.R., Xiao, T.L., Zhang, B., Armstrong, D.W., Super/subcritical fluid chromatography chiral separations with macrocyclic glycopeptide stationary phases, J. Chromatogr. A., 978, 185-204 (2002).
9. Bernal, J.L., Toribio, L., del Nozal, M.J., Nieto, E.M., Jimenez, J.J., Chiral separation of four 1,3-dioxolane derivatives by supercritical fluid chromatography on an amylose-based column, J. Chromatogr. A., 871, 127-137 (2000).
10. Schoenmakers, P.J., Louis, G.M., Janssen, H.G., Comparison of stationary phases for packed-column supercritical fluid chromatography, J. Chromatogr., 506, 563-578 (1990).
11. Macaudiére, P., Caude, M., Rosset, R., Tambuté, A., Chiral resolutions in SFC: Mechanisms and applications with various chiral stationary phases, J. Chromatogr. Sci., 27, 583-591 (1989).
12. Villeneuve, M.S., Anderegg, R.J., Analytical supercritical fluid chromatography using fully automated column and modifier selection valves for the rapid development of chiral separations, J. Chromatogr. A., 826, 217-225 (1998).
13. Bhusham, R., Martens, J. Resolution of enantiomers of ibuprofen by liquid chromatography: A review, Biomed. Chromatogr., 12, 309 (1998).
14. Terfloth, G.J., Pirkle, W.H., Lynam, K.G., Nicolas, E.C., Broadly applicable polysiloxane-based chiral stationary phase for high-performance liquid chromatography and supercritical fluid chromatography, J. Chromatogr. A, 705, 185 (1995).
15. Williams, K.L., Sander, L.C., Wise, S.A., Comparison of liquid and supercritical fluid chromatography for the separation of enantiomers on chiral stationary phases, J. Pharm. Biomed. Anal., 15, 1789 (1997).
16. Blum, A.M., Lynam, K.G., Nicolas, E.C., Use of a new pirkle-type chiral stationary phase in analytical and preparative subcritical fluid chromatography of pharmaceutical compounds, Chirality, 6, 302 (1994).
17. Overbeke, A., Sandra, P., Medvedovici, A., Baeyens, W., Aboul-Enein, H.Y., Application of chiralcel OJ in supercritical fluid chromatography for the resolution of different groups of frequently used drug racemates, Chirality, 9, 126 (1997).
18. Kot, A., Sandra, P., Venema, A., Sub-and supercritical fluid chromatography on packed columns: A versatile tool for the enantioselective separation of basic and acidic drugs, J. Chromatogr. Sci., 32, 439 (1994).
19. Wilson, W.H., Direct enantiomeric resolution of ibuprofen and flurbiprofen by packed column SFC, Chirality, 6, 216 (1994).
20. Depta, A., Giese, T., Johannsen, M., Brunner, G., Separation of stereoisomers in a simulated moving bed-supercritical fluid chromatography plant, J. Chromatogr. A, 865, 175 (1999).
21. Johannsen, M.J., Separation of enantiomers of ibuprofen on chiral stationary phases by packed column supercritical fluid chromatography, J. Chromatogr. A, 937, 135 (2001).
22. Tan, S.C., Patel, B.K., Jackson, S.H.D., Swift, C.G., Hutt, A.J., Ibuprofen stereochemistry: Double-the-trouble?, Enantiomer, 4, 195-203 (1999).