Intravenous immunoglobulin inhibits anti-glycoprotein IIb-induced platelet apoptosis in a murine model of immune thrombocytopenia

British Journal of Haematology

Volumn 133, Issue 1, 2006, Pages 78-82

  Leytin, Valery ^a,b,c   Mykhaylov, Sergiy ^a   Starkey, Alison F ^a,d   Allen, David J ^a   Lau, Herbert ^a,c   Ni, Heyu ^a,b,c,d   Semple, John W ^a,b,c,d   Lazarus, Alan H ^a,b,c,d   Freedman, John ^a,b,c  

^a ST MICHAEL'S HOSPITAL   (Canada)

^b Toronto Hamilton Platelet Immunobiology Group   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

^d UNIVERSITY OF TORONTO   (Canada)

Author keywords

Anti glycoprotein IIb antibody; Immune thrombocytopenia; Intravenous immunoglobulin; Murine model; Platelet apoptosis

Indexed keywords

CASPASE 3; GLYCOPROTEIN IIB; IMMUNOGLOBULIN; PHOSPHATIDYLSERINE; PROTEIN ANTIBODY;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; AUTOIMMUNE THROMBOCYTOPENIA; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVATION; EXPERIMENTAL MODEL; MEMBRANE DEPOLARIZATION; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; MOUSE; NONHUMAN; PRIORITY JOURNAL; THROMBOCYTE DISORDER;

ANIMALS; APOPTOSIS; AUTOANTIBODIES; BLOOD PLATELETS; CASPASE 3; CASPASES; DEPRESSION, CHEMICAL; ENZYME ACTIVATION; IMMUNOGLOBULINS, INTRAVENOUS; IMMUNOLOGIC FACTORS; MEMBRANE POTENTIALS; MICE; MICE, INBRED C57BL; MITOCHONDRIAL MEMBRANES; MODELS, ANIMAL; PHOSPHATIDYLSERINES; PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX; THROMBOCYTOPENIA;

EID: 33644639028     PISSN: 00071048     EISSN: 13652141     Source Type: Journal    
DOI: 10.1111/j.1365-2141.2006.05981.x     Document Type: Article

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