Relationships between skin test, specific IgE and levels of cytokines in patients with penicillin allergy

International Journal of Clinical Practice

Volumn 59, Issue 8, 2005, Pages 895-899

  Qiao, Hai Ling ^a   Liu, J H ^a   Yang, J ^a   Dong, Z M ^a  

^a ZHENGZHOU UNIVERSITY   (China)

Author keywords

Allergy; IFN ; IL 13; IL 4; Penicillins; Specific IgE

Indexed keywords

AMOXICILLIN; AMPICILLIN; CYTOKINE; GAMMA INTERFERON; IMMUNOGLOBULIN E; INTERLEUKIN 13; INTERLEUKIN 4; PENICILLIN G; PENICILLIN V; ANTIBODY; EPITOPE; PENICILLIN DERIVATIVE;

ADULT; ANTIBODY DETECTION; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; CORRELATION ANALYSIS; DRUG FEVER; DYSPNEA; ERYTHEMA; FEMALE; HUMAN; IMMUNOGLOBULIN BLOOD LEVEL; IMMUNOREACTIVITY; MAJOR CLINICAL STUDY; MALE; PENICILLIN ALLERGY; PRIORITY JOURNAL; PRURITUS; RADIOALLERGOSORBENT TEST; SKIN TEST; URTICARIA; ANTIBODY SPECIFICITY; BLOOD; COMPARATIVE STUDY; DRUG HYPERSENSITIVITY; IMMEDIATE TYPE HYPERSENSITIVITY; IMMUNOLOGY; NONPARAMETRIC TEST; SENSITIVITY AND SPECIFICITY;

ADULT; ANTIBODIES; ANTIBODY SPECIFICITY; CYTOKINES; DRUG HYPERSENSITIVITY; EPITOPES; FEMALE; HUMANS; HYPERSENSITIVITY, IMMEDIATE; IMMUNOGLOBULIN E; INTERFERON TYPE II; INTERLEUKIN-13; INTERLEUKIN-4; MALE; PENICILLINS; RADIOALLERGOSORBENT TEST; SENSITIVITY AND SPECIFICITY; SKIN TESTS; STATISTICS, NONPARAMETRIC;

EID: 33644638738     PISSN: 13685031     EISSN: 17421241     Source Type: Journal    
DOI: 10.1111/j.1742-1241.2005.00496.x     Document Type: Article

References (25)

1. Erffmeyer JE. Adverse reactions to penicillin. Ann Allergy 1981; 47: 288-93.
2. Sher TH. Penicillin hypersensitivity - a review. Pediatr Clin North Am 1983; 30: 161-76.
3. Lin RY. A perspective on penicillin allergy. Arch Intern Med 1992; 152: 930-7.
4. Kraft D, Wide L. Clinical patterns and results of radioallergosorbent test (RAST) and skin tests in penicillin allergy. Br J Dermatol 1976; 94: 593-601.
5. Blanca M, Torres MJ, Mayorga C et al. In vitro methods for quantifying IgE antibodies to betalactams. Allergy 1999; 54: 8-11.
6. Beeley L. Allergy to penicillin. BMJ 1984; 288: 511-2.
7. Coleman JW, Blanca M. Mechanisms of drug allergy. Immunol Today 1998; 19: 196-8.
8. Kerdine S, Lebrec H, Bertoglio J et al. Interleukin-4 plays a dominant role in Th1- or Th2-like responses during the primary immune response to the hapten penicillin. Mol Immunol 1996; 33: 71-7.
9. Hertl M, Bohlen H, Jugert F et al. Predominance of epidermal CD8+ T lymphocytes in bullous cutaneous reactions caused by beta-lactam antibiotics. J Invest Dermatol 1993; 101: 794-9.
10. Brander C, Mauri-Hellweg D, Bettens F et al. Heterogeneous T cell responses to beta-lactam-modified self-structures are observed in penicillin-allergic individuals. J Immunol 1995; 155: 2670-8.
11. Zhao ZJ, Batley MD, D'Ambrosio C et al. In vitro reactivity of penicilloyl and penicillanyl albumin and polylysine conjugates with IgE-antibody. J Immunol Methods 2000; 242: 43-51.
12. Zhao YX, Qiao HL. Detection of specific IgE antibodies to major and minor antigenic determinants in sera of penicillin allergic patients. Chin Med J (Engl) 2003; 116: 1904-10.
13. Qiao HL, Yang J, Zhang YW. Specific serum IgE levels and FcεRIβ genetic polymorphism in patients with penicillins allergy. Allergy 2004; 59: 1326-32.
14. Torres MJ, Mayorga C, Pamies R et al. Immunologic response to different determinants of benzylpenicillin, amoxicillin, and ampicillin. Comparison between urticaria and anaphylactic shock. Allergy 1999; 54: 936-43.
15. Green GR, Rosenblum AH, Sweet LC. Evaluation of penicillin hypersensitivity: Value of clinical history and skin testing with penicilloyl-polylysine and penicillin G. A cooperation prospective study of the penicillin study group of the American Academy of Allergy. J Allergy Clin Immunol 1977; 60: 339-45.
16. Blanca M, Vega JM, Garcia J et al. New aspects of allergic reactions to betalactamas: Crossreactions and unique specificities. Clin Exp Allergy 1994; 24: 407-15.
17. Baldo BA, Pham NH, Weiner J. Detection and side-chain specificity of IgE antibodies to flueloxacillin in allergic subjects. J Mol Recognit 1995; 8: 171-7.
18. Mendelson LM, Ressler C, Rosen JP et al. Routine elective penicillin allergy skin testing in children and adolescents: Study of sensitization. J Allergy Clin Immunol 1984; 73: 76-81.
19. Witteman AM, Stapel SO, Perdok GJ et al. The relationship between RAST and skin test results in patients with asthma or rhinitis: A quantitative study with purified major allergens. J Allergy Clin Immunol 1996; 97: 16-25.
20. Adkinson NF. Quantitative studies of the IgE and IgG immune response to penicillin administration in man. Ann Allergy 1977; 39: 73-7.
21. Romagnani S. Human Th1 and Th2 subsets: Doubt no more. Immunol Today 1991; 12: 256-7.
22. Maggi E, Parronchi P, Manetti R et al. Reciprocal regulatory effects of IFN-gamma and IL-4 on the in vitro development of human Th1/Th2 clones. J Immunol 1992; 148: 2142-7.
23. Brugnolo F, Annunziato F, Sampognaro S et al. Highly Th2-skewed cytokine profile of beta-lactam-specific T cells from nonatopic subjects with adverse drug reactions. J Immunol 1999; 163: 1053-9.
24. Noguchi E, Nukaga-Nishio Y, Jian Z et al. Haplotypes of the 5′ region of the IL-4 gene and SNPs in the intergene sequence between the IL-4 and IL-13 genes are associated with atopic asthma. Hum Immunol 2001; 62: 1251-7.
25. Li L, Xia Y, Nguyen A et al. Effects of Th2 cytokines on chemokine expression in the lung: IL-13 potently induces eotaxin expression by airway epithelial cells. J Immunol 1999; 162: 2477-87.