The effects of the Roche AMPLICOR HIV-1 MONITOR® UltraSensitive Test versions 1.0 and 1.5 viral load assays and plasma collection tube type on determination of response to antiretroviral therapy and the inappropriateness of cross-study comparisons

Journal of Clinical Virology

Volumn 35, Issue 4, 2006, Pages 420-425

  Giordano, Michael ^a   Kelleher, Thomas ^a   Colonno, Richard J ^a   Lazzarin, Adriano ^b   Squires, Kathleen ^c  

^a BRISTOL MYERS SQUIBB   (United States)

^b Department of Neurosurgery   (Italy)

^c THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

Antiretroviral therapy; Clinical trials; Cross study comparisons; HIV sequence variability subtypes; Plasma collection procedures; Polymerase chain reaction; Viral load

Indexed keywords

ATAZANAVIR; EDETIC ACID; EFAVIRENZ; LAMIVUDINE; VIRUS RNA; ZIDOVUDINE;

ARTICLE; BLOOD SAMPLING; CLINICAL TRIAL; COMPUTER PROGRAM; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG DOSE REGIMEN; DRUG EFFICACY; DRUG SAFETY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INTERMETHOD COMPARISON; MAJOR CLINICAL STUDY; MONITOR; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SENSITIVITY ANALYSIS; VIRUS LOAD;

ANTI-HIV AGENTS; BLOOD SPECIMEN COLLECTION; DNA PRIMERS; DRUG THERAPY, COMBINATION; EDETIC ACID; HIV INFECTIONS; HIV PROTEASE INHIBITORS; HIV-1; HUMANS; INTERNATIONALITY; NUCLEIC ACID AMPLIFICATION TECHNIQUES; OLIGOPEPTIDES; OXAZINES; PYRIDINES; RANDOMIZED CONTROLLED TRIALS; REAGENT KITS, DIAGNOSTIC; REVERSE TRANSCRIPTASE INHIBITORS; RNA, VIRAL; TREATMENT OUTCOME; VIRAL LOAD;

EID: 33644636495     PISSN: 13866532     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jcv.2005.10.011     Document Type: Article

References (10)

1. D.J. Brambilla, C. Jennings, R. Morack, S. Granger, and J.W. Bremer Comparison of the sensitivities of the version 1.5 and version 1.0 ultrasensitive Roche AMPLICOR HIV-1 MONITOR kits at low concentrations of human immunodeficiency virus RNA J Clin Microbiol 42 2004 2819 2820
2. M. Holodniy, L. Mole, B. Yen-Lieberman, D. Margolis, C. Starkey, and R. Carroll Comparative stabilities of quantitative human immunodeficiency virus RNA in plasma from samples collected in VACUTAINER CPT, VACUTAINER PPT, and standard VACUTAINER tubes J Clin Microbiol 33 1995 1562 1566
3. J.B. Jackson, E. Piwowar-Manning, L. Johnson-Lewis, R. Bassett, L.M. Demeter, and D. Brambilla Comparison of versions 1.0 and 1.5 of the UltraSensitive AMPLICOR HIV-1 MONITOR test for subjects with low viral load J Clin Microbiol 42 2004 2774 2776
4. Liegler T, Grant RM. HIV viral load assays; 2001 (web site: http://hivinsite.ucsf.edu/InSite.jsp?page=kb-02-02-02-01 ; accessed: August 15, 2003).
5. N.L. Michael, S.A. Herman, S. Kwok, K. Dreyer, J. Wang, and C. Christopherson Development of calibrated viral load standards for group M subtypes of human immunodeficiency virus type 1 and performance of an improved AMPLICOR HIV-1 MONITOR test with isolates of diverse subtypes J Clin Microbiol 37 1999 2557 2563
6. S. Osmanov, C. Pattou, N. Walker, B. Schwardlënder, J. Esparza and the WHO-UNAIDS Network for HIV Isolation and Characterization Estimated global distribution and regional spread of HIV-1 genetic subtypes in the year 2000 J Acquir Immune Defic Syndr 29 2002 184 190
7. A. Phillips Trial and error: cross-trial comparisons of antiretroviral regimens AIDS 17 2003 619 623
8. K. Squires, A. Lazzarin, J.M. Gatell, W.G. Powderly, V. Pokrovskiy, and J.-F. DelFraissy Comparison of once-daily atazanavir with efavirenz, each in combination with fixed-dose zidovudine and lamivudine, as initial therapy for patients infected with HIV J Acquir Immune Defic Syndr 36 2004 1011 1019
9. S. Staszewski, J. Morales-Ramirez, K.T. Tashima, A. Rachlis, D. Skiest, J. Stanford for the Study 006 Team Efavirenz plus zidovudine and lamivudine, efavirenz plus indinavir, and indinavir plus zidovudine and lamivudine in the treatment of HIV-1 infection in adults N Engl J Med 341 1999 1865 1873
10. K. Triques, J. Coste, J.L. Perret, C. Segarra, E. Mpoudi, and J. Reynes Efficiencies of four versions of the AMPLICOR HIV-1 MONITOR test for quantification of different subtypes of human immunodeficiency virus type 1 J Clin Microbiol 37 1999 110 116