Antiviral effects of sophoridine against coxsackievirus B3 and its pharmacokinetics in rats

Life Sciences

Volumn 78, Issue 17, 2006, Pages 1998-2005

  Zhang, Yuanyuan ^a   Zhu, Haiyan ^a   Ye, Guan ^a   Huang, Chenggang ^a   Yang, Yingzhen ^b   Chen, Ruizhen ^b   Yu, Yong ^b   Cui, Xiaolan ^c  

^a SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

^b FUDAN UNIVERSITY   (China)

^c INSTITUTE OF CHINESE MATERIA MEDICA   (China)

Author keywords

Coxsackievirus B3; Cytokines; Pharmacokinetics; Sophoridine; Viral myocarditis

Indexed keywords

CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 10; MESSENGER RNA; SOPHORA FLAVESCENS EXTRACT; SOPHORIDINE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIVIRAL ACTIVITY; ARTICLE; CHINESE MEDICINE; CONTROLLED STUDY; COXSACKIE VIRUS B3; CYTOKINE PRODUCTION; DOSE RESPONSE; DRUG BLOOD LEVEL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HISTOPATHOLOGY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VIRUS MYOCARDITIS;

ALKALOIDS; ANIMALS; ANTIVIRAL AGENTS; CELLS, CULTURED; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COXSACKIEVIRUS INFECTIONS; CYTOKINES; DISEASE MODELS, ANIMAL; DRUGS, CHINESE HERBAL; ENTEROVIRUS B, HUMAN; LONGEVITY; MALE; MICE; MICE, INBRED BALB C; MYOCARDITIS; MYOCYTES, CARDIAC; QUINOLIZINES; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; SURVIVAL RATE; VIRUS REPLICATION;

ANIMALIA; COXSACKIEVIRUS; MURINAE; SOPHORA FLAVESCENS;

EID: 33644622747     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2005.09.034     Document Type: Article

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