Adjuvant topical interferon-α-2b treatment in epithelial tumors of the ocular surface;Adjuvante topische interferon-α-2b-therapie bei epithelialen tumoren der augenoberfläche

Ophthalmologe

Volumn 103, Issue 2, 2006, Pages 124-128

  Fuchsluger, T A ^a   Hintschich, C ^b   Steuhl, K P ^a   Meller, D ^a  

^a UNIVERSITY HOSPITAL ESSEN   (Germany)

^b LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

Author keywords

Amniotic membrane; Conjunctival intraepithelial neoplasia; Excisional biopsy; Interferon; Ocular surface

Indexed keywords

ALPHA2B INTERFERON; ANTIMETABOLITE; FLUOROURACIL; MITOMYCIN C; RECOMBINANT ALPHA2B INTERFERON;

ADULT; AGED; AMNION; ARTICLE; CANCER RADIOTHERAPY; CASE REPORT; CONJUNCTIVAL HYPEREMIA; CRYOTHERAPY; DRUG EFFICACY; DRUG SAFETY; EPITHELIUM TUMOR; EXCISION; EYE SURGERY; EYE TUMOR; FEMALE; FOLLOW UP; HISTOLOGY; HUMAN; HUMAN PAPILLOMAVIRUS TYPE 16; HUMAN PAPILLOMAVIRUS TYPE 18; HYBRIDIZATION; MALE; MEDICAL RECORD; PATIENT; PROSPECTIVE STUDY; TUMOR BIOPSY; TUMOR RECURRENCE; WART VIRUS;

EID: 33644618102     PISSN: 0941293X     EISSN: 14330423     Source Type: Journal    
DOI: 10.1007/s00347-005-1249-8     Document Type: Article

References (35)

1. Ateenyi-Agaba C, Weiderpass E, Smet A et al. (2004) Epidermoid dysplasia verruciformis human papilloma virus types and carcinoma of the conjunctiva: a pilot study. Br J Cancer 90(9):1777-1779
2. Baron S, Tyring SK, Fleischmann WR et al. (1991) The interferons: mechanisms of action and clinical applications. JAMA 266:1375-1383
3. Berman B, Sequeira M (1995) Dermatologic uses of interferons. Curr Ther 13:699-711
4. Cerezo L, Otero J, Aragon G et al. (1990) Conjunctival intraepithelial and invasive squamous cell carcinoma treated with strontium-90. Radiother Oncol 17:191-197
5. Di Pascuale MA, Espana EM, Tseng SC (2004) A case of conjunctiva-cornea intraepithelial neoplasia sucessfully treated with topical mitomycin C and interferon alfa-2b in cycles. Cornea 23(1):89-92
6. Edwards I, Berman B, Rapini RP et al. (1992) Treatment of cutaneous squamous cell carcinomas by intralesional interferon alpha 2b therapy. Arch Dermatol 128:1486-1489
7. Erie JC, Campbell RJ, Leisegang TJ (1986) Conjunctival and corneal intraepithelial and invasive neoplasia. Ophthalmology 93:176-183
8. Grossniklaus HE, Green WR, Luckenbach M et al. (1987) Conjunctival lesions in adults: a clinical and histopathologic review. Cornea 6:78-116
9. Hu FR, Wu MJ, Kuo SH (1998) Interferon treatment for corneolimbal squamous dysplasia. Am J Ophthalmol 125(1):118-119
10. Isaacs A, Lindemann J (1957) Virus interferons, I. Interferon. Proc R Soc London Biol 147:258-267
11. Karp CL, Scott IU, Chang TS et al. (1996) Conjunctival intraepithelial neoplasia. Arch Ophthalmol 114:257-261
12. Karp CL, Moore JK, Rosa RH (2001) Treatment of conjunctival and corneal intraepithelial neoplasia with topical interferon alpha-2b. Ophthalmology 108(6):1093-1098
13. Kobayashi A, Yoshita T, Uchiyama K (2002) Successful management of conjunctival intraepithelial neoplasia by interferon alpha-2b. Jpn J Ophthalmol 46(2):215-217
14. Lee GA, Williams G, Hirst LW et al. (1994) Risk factors in the development of ocular surface epithelial dysplasia. Ophthalmology 101(2):360-364
15. Lippmann SM, Kavanagh JJ, Paredes-Espinoza M et al. (1992) 13-cisretonic acid plus interferon alpha 2a: highly active systemic therapy for squamous cell carcinoma of the cervix. J Natl Cancer Inst 84:241-245
16. Maskin SL (1994) Regression of limbal epithelial dysplasia with topical interferon. Arch Ophthalmol 112:1145-1146
17. Morlet N, Gillies MC, Crouch R, Maloof A (1993) Effect of topical interferon-alpha 2b on corneal haze after excimer laser photorefractive keratectomy in rabbits. Refract Corneal Surg 9:443-451
18. Napora C, Cohen E, Genvert GI et al. (1990) Factors associated with CIN. Ophthal Surg 21:27-30
19. Nedelec B, Shen YJ, Ghahary A, Scott PG, Tredget EE (1995) The effect of interferon alpha 2b on the expression of cytoskeletal proteins in an in vitro model of wound contraction. J Lab Clin Med 126:474-484
20. Nedelec B, Shankowsky H, Scott PG, Ghahary A, Tredget EE (2001) Myofibroblasts and apoptosis in human hypertrophic scars: the effect of interferon-alpha 2b. Surgery 130:789-808
21. Peksayaar G, Soyturk MK, Demiryont M (1989) Long term results of cryotherapy on malignant epithelial tumors of the conjunctiva. Am J Ophthalmol 107:337-349
22. Pizzarello LD, Jakobiec FA (1978) Bowen's disease of the conjunctiva: a misnomer. In: Jakobiec FA (ed) Ocular and adnexal tumors. Aesculapius, Birmingham, pp 553-571
23. Sanders N, Bedotto C (1972) Recurrent carcinoma in situ of the conjunctiva and cornea. Am J Ophthalmol 74:688-693
24. Schechter BA, Rand WJ, Velazquez GE et al. (2002) Treatment of conjunctival papillomata with topical interferon alfa-2b. Am J Ophthalmol 134(2):268-270
25. Schechter BA, Schreir A, Nagler RS et al. (2002) Regression of presumed primary conjunctival and corneal intraepithelial neoplasia with topical interferon alpha-2b. Cornea 21(1):6-11
26. Scott IU, Karp CL, Nouvo GJ (2002) Human papillomavirus 16 and 18 expression in conjunctiva intraepithelial neoplasia. Ophthalmology 109(3):542-547
27. Seitz B, Fischer M, Holbach LM et al. (1995) Differential diagnosis and prognosis of 112 excised epibulbar epithelial tumors. Klin Monatsbl Augenheilkd 207(4):239-246
28. Sjo NC, Heegaard S, Prause JA et al. (2001) Human papillomavirus in conjunctival papilloma. Br J Ophthalmology 85:785-787
29. Smith M, Trousdale MD, Rao N et al. (1989) Lack of toxicity of a topical recombinant interferon. Cornea 8:58-61
30. Tabin G, Levin S, Snibson G et al. (1997) Late recurrences and the necessity for long term follow up in corneal and conjunctival intraepithelial neoplasia. Ophthalmology 104:485-492
31. Takeuchi M, Tredget EE, Scott PG, Kilani RT, Ghahary A (1999) The antifibrogenic effects of liposome-encapsulated IFN-alpha 2b cream on skin wounds. J Interferon Cytokine Res 19:1413-1419
32. Tredget EE, Wang R, Shen Q, Scott PG, Ghahary A (2000) Transforming growth factor-beta mRNA and protein in hypertrophic scar tissues and fibroblasts: antagonism by IFN-alpha and IFN-gamma in vitro and in vivo. J Interferon Cytokine Res 20:143-151
33. Toledano Fernandez N, Garcia Saenz S, Diaz Valle D et al. (2003) Interferon alfa-2b treatment in selected cases of recurrent conjunctival intraepithelial neoplasia. Arch Soc Esp Oftalmol 78(5):265-271
34. Vann RR, Karp CL (1999) Perilesional and topical interferon alfa-2b for conjunctival and corneal neoplasia. Ophthalmology 106(1):91-97
35. Zhang X, Peng D, Zheng H et al. (1997) Lack of corneal toxicity of interferon alpha-2b administered subconjunctivally after sclerectomy. Yan Ke Xue Bao 13(1):35-37