Treatment of severe disseminated juvenile systemic xanthogranuloma with multiple lesions in the central nervous system

Journal of Pediatric Hematology/Oncology

Volumn 28, Issue 2, 2006, Pages 95-97

  Dölken, Regina ^a,c   Weigel, Steffen ^a   Schröder, Henry ^a   Hartwig, Maite ^a   Harms, Dieter ^b   Beck, James F ^a  

^a UNIVERSITY OF GREIFSWALD   (Germany)

^b UNIVERSITY OF KIEL   (Germany)

^c Abteilung fur Padiatrische Onkologie   (Germany)

Author keywords

Central nervous system lesions; Langerhans cell histiocytosis; Multiagent chemotherapy; Systemic juvenile xanthogranuloma

Indexed keywords

ETOPOSIDE; MERCAPTOPURINE; METHOTREXATE; PREDNISOLONE; VINBLASTINE;

ARTICLE; CANCER CHEMOTHERAPY; CASE REPORT; CELL PROLIFERATION; CENTRAL NERVOUS SYSTEM DISEASE; DISEASE SEVERITY; FEMALE; HEPATOMEGALY; HISTOLOGY; HUMAN; HUMAN TISSUE; INFANT; JUVENILE XANTHOGRANULOMA; KIDNEY DISEASE; LIVER DISEASE; LUNG DISEASE; MULTIMODALITY CANCER THERAPY; MULTIPLE TRAUMA; PRIORITY JOURNAL; PROGNOSIS; REMISSION; SCALP; SKIN DEFECT;

6-MERCAPTOPURINE; CENTRAL NERVOUS SYSTEM DISEASES; COMBINED MODALITY THERAPY; CRANIOTOMY; DRUG THERAPY, COMBINATION; FEMALE; FOLLOW-UP STUDIES; HUMANS; INFANT; INJECTIONS, SPINAL; LIVER DISEASES; LUNG DISEASES; METHOTREXATE; PARESIS; PREDNISOLONE; SKIN DISEASES; VINBLASTINE; XANTHOGRANULOMA, JUVENILE;

EID: 33644613679     PISSN: 10774114     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.mph.0000199588.83679.76     Document Type: Article

References (10)

1. Dehner LP. Juvenile xanthogranulomas in the first two decades of life: a clinicopathologic study of 174 cases with cutaneous and extracutaneous manifestations. Am J Surg Pathol. 2003;27:579-593.
2. Adamson N. Congenital xanthoma multiplex in a child. Br J Dermatol. 1905;17:222-223.
3. Freyer DR, Kennedy R, Bostrom BC, et al. Juvenile xanthogranuloma: forms of systemic disease and their clinical implications. J Pediatr. 1996;129:227-237.
4. Bostrom J, Janssen G, Messing-Junger M, et al. Multiple intracranial juvenile xanthogranulomas. Case report. J Neurosurg. 2000;93:335-341.
5. Caputo R, Ermacora E, Gelmetti C, et al. Fatal nodular xanthomatosis in an infant. Pediatr Dermatol. 1987;4:242-246.
6. Tomaszewski MM, Lupton GP. Unusual expression of S-100 protein in histiocytic neoplasms. J Cutan Pathol. 1998;25:129-135.
7. Flach DB, Winkelmann RK. Juvenile xanthogranuloma with central nervous system lesions. J Am Acad Dermatol. 1986;14:405-411.
8. Janssen D, Harms D. Juvenile xanthogranuloma in childhood and adolescence: a clinicopathologic study of 129 patients from the Kiel pediatric tumor registry. Am J Surg Pathol. 2005;29:21-28.
9. Favara BE, Feller AC, Pauli M, et al. Contemporary classification of histiocytic disorders. The WHO Committee on Histiocytic/Reticulum Cell Proliferations. Reclassification Working Group of the Histiocyte Society. Med Pediatr Oncol. 1997;29:157-166.
10. Nakatani T, Morimoto A, Kato R, et al. Successful treatment of congenital systemic juvenile xanthogranuloma with Langerhans cell histiocytosis-based chemotherapy. J Pediatr Hematol Oncol. 2004;26:371-374.