Analysis of the antibacterial activity and plaque control benefit of Colgate® Total® dentifrice via clinical evaluation and real-time polymerase chain reaction

Journal of Clinical Dentistry

Volumn 16, Issue 4, 2005, Pages 117-122

  Xu, Tao ^a   Deshmukh, Meenal ^a   Barnes, Virginia Monsul ^a   Trivedi, Harsh M ^a   Du Thumm, Laurence ^a   Richter, Rose ^a   Cummins, Diane ^a  

^a Technology Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFECTIVE AGENT; COLGATE TOTAL; CREST REGULAR DENTIFRICE; FLUORIDE; FLUORIDE SODIUM; SILICON DIOXIDE; TOOTHPASTE; TRICLOSAN;

ACTINOBACILLUS ACTINOMYCETEMCOMITANS; ACTINOMYCES; ARTICLE; BACTEROIDES; CLINICAL TRIAL; COMPARATIVE STUDY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DRUG EFFECT; DRUG MIXTURE; EUBACTERIUM; FOLLOW UP; FUSOBACTERIUM NUCLEATUM; HUMAN; METHODOLOGY; MICROBIOLOGY; POLYMERASE CHAIN REACTION; PORPHYROMONAS GINGIVALIS; SINGLE BLIND PROCEDURE; TOOTH PLAQUE;

ACTINOBACILLUS ACTINOMYCETEMCOMITANS; ACTINOMYCES; ANTI-BACTERIAL AGENTS; BACTEROIDES; COMPLEX MIXTURES; CROSS-OVER STUDIES; DENTAL PLAQUE; DENTAL PLAQUE INDEX; DENTIFRICES; EUBACTERIUM; FLUORIDES; FOLLOW-UP STUDIES; FUSOBACTERIUM NUCLEATUM; HUMANS; POLYMERASE CHAIN REACTION; PORPHYROMONAS GINGIVALIS; SILICON DIOXIDE; SINGLE-BLIND METHOD; SODIUM FLUORIDE; TOOTHPASTE; TRICLOSAN;

EID: 33644598500     PISSN: 08958831     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (18)

1. Perry D: Plaque control for the periodontal patient. In: Carranza's Clinical Periodontology 9th Ed. Newman MG, Takai HH, Carranza FA, eds., WB Saunders, Philadelphia, pp. 651-674, 2002.
2. Lavigne SF. Periodontology: Sounder's Review of Dental Hygiene. Nelson DM, ed., WB Saunders, Philadelphia, pp. 394-451, 2000.
3. Xu T, Barnes VM: The development of a new dental probe and a new plaque index. J Clin Dent 14:93-97, 2003.
4. Mackay IM: Real-time PCR in the microbiology laboratory. Clin Microbiol and Infect 10:190-212, 2004.
5. American Dental Association Guidelines for acceptance of chemotherapeutic products for the control of supragingival dental plaque and gingivitis. Council on Dental Therapeutics. JADA 112:529-532, 1986.
6. Silness J, Löe H: Periodontal disease in pregnancy. II. Correlation between oral hygiene and periodontal condition. Acta Odontol Scand 22:121-135, 1964.
7. Quigley GA, Hein JW: Comparative cleansing efficiency of manual and power brushing. JADA 65:26-29, 1962.
8. Harrap GJ: Assessment of the effect of dentifrices on the growth of dental plaque. J Clin Periodontol 1:166-174, 1974.
9. Rupf S, Merte K, Eschrich K: Quantification of bacteria in oral samples by competitive polymerase chain reaction. J Dent Res 78:850-856, 1999.
10. Nadkarni MA, Martin FE, Jacques NA, Hunter N: Determination of bacterial load by real-time PCR using a broad-range (universal) probe and primers set. Microbiol 148:257-266, 2002.
11. Lyons SR, Griffen AL, Leys EJ: Quantitative real-time PCR for porphyromonas gingivalis and total bacteria. J Clin Microbiol 38:2362-2365, 2000.
12. Boutaga K, van Winkelhoff AJ, Vandenbroucke-Grauls CM, Savelkoul PH: Comparison of real-time PCR and culture for detection of porphyromonas gingivalis in subgingival plaque samples. J Clin Microbiol 41:4950-4954, 2003.
13. Maeda H, Fujimoto C, Haruki Y, MaedaT, Kokeguchi S, Petelin M, Arai H, Tanimoto I, Nishimura F, Takashiba S: Quantitative real-time PCR using TaqMan and SYBR Green for actinobacillus actinomycetemcomitans, porphyromonas gingivalis, Prevotella intermedia, tetQ gene and total bacteria. FEMS Immun Med Microbiol 39:81-86, 2003.
14. Riggio MP, Macfariane TW, Mackenzie D, Lennon A, Smith AJ, Kinane D: Comparison of polymerase chain reaction and culture methods for detection of Actinobacillus actinomycetemcomitans and Porphyromonas gingivitis in subgingival plaque samples. J Periodontal Res 31:496-501, 1996.
15. Lindhe J: Triclosan/copolymer/fluoride dentifrices: A new technology for the prevention of plaque, calculus, gingivitis and caries. Am J Dent 3:S3-S4. 1990.
16. Volpe AR, Petrone ME, DeVizio W: A review of plaque, gingivitis, calculus and caries clinical efficacy studies with a fluoride dentifrice containing triclosan and PVM/MA copolymer. J Clin Dent 7 (Suppl):S1-S14, 1996.
17. Gaffar A, Afflitto J, Nabi N, Herles S, Kruger I, Olsen S: Recent advances in plaque, gingivitis, tartar and caries prevention technology. Int Dent J 44:63-70, 1994.
18. Nabi N, Mukerjee C, Schmid R, Gaffar A: In vitro and in vivo studies on triclosan/PVM/MA copolymer/NaF combination as an anti-plaque agent. Am J Dent 2:197-206, 1989.