Macrophage migration inhibitory factor is increased in the urine of patients with urinary tract infection: Macrophage migration inhibitory factor-protein complexes in human urine

Journal of Urology

Volumn 175, Issue 4, 2006, Pages 1523-1528

  Meyer Siegler, Katherine L ^a,b   Iczkowski, Kenneth A ^c   Vera, Pedro L ^a,b  

^a Bay Pines VA Medical Center   (United States)

^b UNIVERSITY OF SOUTH FLORIDA   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Bladder; Cystitis; Inflammation; Macrophage migration inhibitory factors; Urinary tract infections

Indexed keywords

ALBUMIN; ALPHA 2 MACROGLOBULIN; CERULOPLASMIN; MACROPHAGE MIGRATION INHIBITION FACTOR; TAMM HORSFALL GLYCOPROTEIN;

ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CYSTITIS; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; IMMUNOPRECIPITATION; MALE; MASS SPECTROMETRY; MOLECULAR WEIGHT; PRIORITY JOURNAL; PROTEIN DENATURATION; PROTEIN INTERACTION; URINALYSIS; URINARY TRACT INFECTION; WESTERN BLOTTING;

BACTERIAL INFECTIONS; CYSTITIS; FEMALE; HUMANS; MACROPHAGE MIGRATION-INHIBITORY FACTORS; MALE; MULTIPROTEIN COMPLEXES; URINARY TRACT INFECTIONS;

EID: 33644595892     PISSN: 00225347     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-5347(05)00650-6     Document Type: Article

References (20)

1. T.M. Hooton, W.E. Stamm Diagnosis and treatment of uncomplicated urinary tract infection Infect Dis Clin North Am 11 1997 551
2. K.N. Moore, R.A. Day, M. Albers Pathogenesis of urinary tract infections a review J Clin Nurs 11 2002 568
3. F. Backhed, L. Meijer, S. Normark, A. Richter-Dahlfors TLR4-dependent recognition of lipopolysaccharide by epithelial cells requires sCD14 Cell Microbiol 4 2002 493
4. T. Calandra, T. Roger Macrophage migration inhibitory factor a regulator of innate immunity Nat Rev Immunol 3 2003 791
5. T. Roger, J. David, M.P. Glauser, T. Calandra MIF regulates innate immune responses through modulation of Toll-like receptor 4 Nature 414 2001 920
6. K.L. Meyer-Siegler, E.C. Leifheit, P.L. Vera Inhibition of macrophage migration inhibitory factor decreases proliferation and cytokine expression in bladder cancer cells BMC Cancer 4 2004 34
7. K.L. Meyer-Siegler, R.C. Ordorica, P.L. Vera Macrophage migration inhibitory factor is upregulated in an endotoxin-induced model of bladder inflammation in rats J Interferon Cytokine Res 24 2004 55
8. K.L. Meyer-Siegler, P.L. Vera Substance P induced release of macrophage migration inhibitory factor from rat bladder epithelium J Urol 171 2004 1698
9. K.L. Meyer-Siegler, P.L. Vera Intraluminal antibodies to macrophage migration inhibitory factor decrease substance P induced inflammatory changes in the rat bladder and prostate J Urol 172 2004 1504
10. J.A. Baugh, R. Bucala Macrophage migration inhibitory factor Crit Care Med 30 2002 S27
11. R.P. Donn, D.W. Ray Macrophage migration inhibitory factor molecular, cellular and genetic aspects of a key neuroendocrine molecule J Endocrinol 182 2004 1
12. K.L. Meyer-Siegler, M.A. Bellino, M. Tannenbaum Macrophage migration inhibitory factor evaluation compared with prostate specific antigen as a biomarker in patients with prostate carcinoma Cancer 94 2002 1449
13. L. Leng, C.N. Metz, Y. Fang, J. Xu, S. Donnelly, J. Baugh MIF signal transduction initiated by binding to CD74 J Exp Med 197 2003 1467
14. K.L. Meyer-Siegler, P.L. Vera Substance P induced changes in CD74 and CD44 in the rat bladder J Urol 173 2005 615
15. P.L. Vera, K.A. Iczkowski, L. Leng, R. Bucala, K.L. Meyer-Siegler Macrophage migration inhibitory factor is released as a complex with α1-inhibitor-3 in the intraluminal fluid during bladder inflammation in the rat J Urol 174 2005 338
16. K.L. Meyer-Siegler, K.A. Iczkowski, P.L. Vera Further evidence for increased macrophage migration inhibitory factor expression in prostate cancer BMC Cancer 5 2005 73
17. H.Y. Lan, M. Bacher, N. Yang, W. Mu, D.J. Nikolic-Paterson, C. Metz The pathogenic role of macrophage migration inhibitory factor in immunologically induced kidney disease in the rat J Exp Med 185 1997 1455
18. K. Matsumoto, N. Maruyama, T. Maruyama, Y. Ohnishi, S. Nonaka, A. Inoshita Elevated macrophage migration inhibitory factor (MIF) levels in the urine of patients with focal glomerular sclerosis Clin Exp Immunol 139 2005 338
19. R. Engler Acute-phase proteins in inflammation C. R Seances Soc Biol Fil 189 1995 563
20. S.L. Gonias, A. Carmichael, J.M. Mettenburg, D.W. Roadcap, W.P. Irvin, D.J. Webb Identical or overlapping sequences in the primary structure of human alpha(2)-macroglobulin are responsible for the binding of nerve growth factor-beta, platelet-derived growth factor-BB, and transforming growth factor-beta J Biol Chem 275 2000 5826