Class III effects of dofetilide and arrhythmias are modulated by [K +]o in an in vitro model of simulated-ischemia and reperfusion in guinea-pig ventricular myocardium

European Journal of Pharmacology

Volumn 532, Issue 3, 2006, Pages 279-289

  Ducroq, Joffrey ^a,d   Rouet, René ^a   Sallé, Laurent ^a   Puddu, Paolo Emilio ^a,b   Repessé, Yohann ^a   Ghadanfar, Mathieu ^c   Ducouret, Pierre ^a   Gérard, Jean Louis ^a  

^a UNIVERSITÉ DE CAEN   (France)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

^c Worldwide Cardiovascular Group   (United States)

^d Université de Caen ^*  (France)

Author keywords

(Guinea pig); Delayed outward rectifier; Dofetilide; Ischemia reperfusion; Potassium

Indexed keywords

DOFETILIDE; INWARDLY RECTIFYING POTASSIUM CHANNEL; TYKOSIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARRHYTHMOGENESIS; ARTICLE; CONTROLLED STUDY; DISEASE MODEL; DISEASE SIMULATION; DRUG EFFECT; EVALUATION; FEMALE; GUINEA PIG; HEART ARRHYTHMIA; HEART MUSCLE ISCHEMIA; HEART MUSCLE OXYGEN CONSUMPTION; HEART MUSCLE POTENTIAL; HEART MUSCLE REPERFUSION; HEART PROTECTION; HEART REPOLARIZATION; HEART VENTRICLE ARRHYTHMIA; HEART VENTRICLE WALL; IN VITRO STUDY; MALE; NONHUMAN; PRIORITY JOURNAL; RECORDING;

ACTION POTENTIALS; ANIMALS; ANTI-ARRHYTHMIA AGENTS; ARRHYTHMIA; DOSE-RESPONSE RELATIONSHIP, DRUG; GUINEA PIGS; HEART; HEART VENTRICLES; HYPERKALEMIA; KINETICS; MODELS, ANIMAL; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM; PHENETHYLAMINES; POTASSIUM; POTASSIUM CHANNEL BLOCKERS; SULFONAMIDES;

EID: 33644546682     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2005.12.083     Document Type: Article

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