-
1
-
-
15544381256
-
Prevention and management of hereditary breast cancer
-
Narod SA, Offit K. Prevention and management of hereditary breast cancer. J Clin Oncol 2005;23:1656-63.
-
(2005)
J Clin Oncol
, vol.23
, pp. 1656-1663
-
-
Narod, S.A.1
Offit, K.2
-
2
-
-
0037087536
-
Clinical characteristics of individuals with germline mutations in BRCA1 and BRCA2: Analysis of 10,000 individuals
-
Frank TS, Deffenbaugh AM, Reid JE, et al. Clinical characteristics of individuals with germline mutations in BRCA1 and BRCA2: analysis of 10,000 individuals. J Clin Oncol 2002;20:1480-90.
-
(2002)
J Clin Oncol
, vol.20
, pp. 1480-1490
-
-
Frank, T.S.1
Deffenbaugh, A.M.2
Reid, J.E.3
-
3
-
-
0029849461
-
Genome: Coming to grips with genes and risk
-
Kahn P. Genome: coming to grips with genes and risk. Science 1996;274:496-8.
-
(1996)
Science
, vol.274
, pp. 496-498
-
-
Kahn, P.1
-
4
-
-
0037417814
-
Understanding missense mutations in the BRCA1 gene: An evolutionary approach
-
Fleming MA, Potter JD, Ramirez CJ, Ostrander GK, Ostrander EA. Understanding missense mutations in the BRCA1 gene: an evolutionary approach. Proc Natl Acad Sci U S A 2003;100:1151-6.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 1151-1156
-
-
Fleming, M.A.1
Potter, J.D.2
Ramirez, C.J.3
Ostrander, G.K.4
Ostrander, E.A.5
-
5
-
-
3142699826
-
Analysis of missense variation in human BRCA1 in the context of interspecific sequence variation
-
Abkevich V, Zharkikh A, Deffenbaugh AM, et al. Analysis of missense variation in human BRCA1 in the context of interspecific sequence variation. J Med Genet 2004;41:492-507.
-
(2004)
J Med Genet
, vol.41
, pp. 492-507
-
-
Abkevich, V.1
Zharkikh, A.2
Deffenbaugh, A.M.3
-
6
-
-
21144453885
-
Phenotype-genotype correlation in Hirschsprung disease is illuminated by comparative analysis of the RET protein sequence
-
Kashuk CS, Stone EA, Grice EA, et al. Phenotype-genotype correlation in Hirschsprung disease is illuminated by comparative analysis of the RET protein sequence. Proc Natl Acad Sci U S A 2005;102:8949-54.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 8949-8954
-
-
Kashuk, C.S.1
Stone, E.A.2
Grice, E.A.3
-
7
-
-
0037459341
-
Variation on an Src-like theme
-
Harrison SC. Variation on an Src-like theme. Cell 2003;112:737-40.
-
(2003)
Cell
, vol.112
, pp. 737-740
-
-
Harrison, S.C.1
-
8
-
-
17844401527
-
Nobel Lecture. Potassium channels and the atomic basis of selective ion conduction
-
Mackinnon R. Nobel Lecture. Potassium channels and the atomic basis of selective ion conduction. Biosci Rep 2004;24:75-100.
-
(2004)
Biosci Rep
, vol.24
, pp. 75-100
-
-
Mackinnon, R.1
-
9
-
-
0034809456
-
Crystal structure of the BRCT repeat region from the breast cancer-associated protein BRCA1
-
Williams RS, Green R, Glover JN. Crystal structure of the BRCT repeat region from the breast cancer-associated protein BRCA1. Nat Struct Biol 2001;8:838-42.
-
(2001)
Nat Struct Biol
, vol.8
, pp. 838-842
-
-
Williams, R.S.1
Green, R.2
Glover, J.N.3
-
10
-
-
0037462647
-
Structural consequences of a cancer-causing BRCA1-BRCT missense mutation
-
Williams RS, Glover JN. Structural consequences of a cancer-causing BRCA1-BRCT missense mutation. J Biol Chem 2003;278:2630-5.
-
(2003)
J Biol Chem
, vol.278
, pp. 2630-2635
-
-
Williams, R.S.1
Glover, J.N.2
-
11
-
-
0036317926
-
Characterisation of the BRCT domains of the breast cancer susceptibility gene product BRCA1
-
Ekblad CM, Wilkinson HR, Schymkowitz JW, Rousseau F, Freund SM, Itzhaki LS. Characterisation of the BRCT domains of the breast cancer susceptibility gene product BRCA1. J Mol Biol 2002;320:431-42.
-
(2002)
J Mol Biol
, vol.320
, pp. 431-442
-
-
Ekblad, C.M.1
Wilkinson, H.R.2
Schymkowitz, J.W.3
Rousseau, F.4
Freund, S.M.5
Itzhaki, L.S.6
-
12
-
-
2542490186
-
Structural basis of phosphopeptide recognition by the BRCT domain of BRCA1
-
Williams RS, Lee MS, Hau DD, Glover JN. Structural basis of phosphopeptide recognition by the BRCT domain of BRCA1. Nat Struct Mol Biol 2004;11:519-25.
-
(2004)
Nat Struct Mol Biol
, vol.11
, pp. 519-525
-
-
Williams, R.S.1
Lee, M.S.2
Hau, D.D.3
Glover, J.N.4
-
13
-
-
6344287454
-
Interactions between BRCT repeats and phosphoproteins: Tangled up in two
-
Glover JN, Williams RS, Lee MS. Interactions between BRCT repeats and phosphoproteins: tangled up in two. Trends Biochem Sci 2004;29:579-85.
-
(2004)
Trends Biochem Sci
, vol.29
, pp. 579-585
-
-
Glover, J.N.1
Williams, R.S.2
Lee, M.S.3
-
14
-
-
0034814783
-
With the ends in sight: Images from the BRCA1 tumor suppressor
-
Baer R. With the ends in sight: images from the BRCA1 tumor suppressor. Nat Struct Biol 2001;8:822-4.
-
(2001)
Nat Struct Biol
, vol.8
, pp. 822-824
-
-
Baer, R.1
-
15
-
-
11144310680
-
Solution structure, backbone dynamics, and association behavior of the C-terminal BRCT domain from the breast cancer-associated protein BRCA1
-
Gaiser OJ, Ball LJ, Schmieder P, et al. Solution structure, backbone dynamics, and association behavior of the C-terminal BRCT domain from the breast cancer-associated protein BRCA1. Biochemistry 2004;43:15983-95.
-
(2004)
Biochemistry
, vol.43
, pp. 15983-15995
-
-
Gaiser, O.J.1
Ball, L.J.2
Schmieder, P.3
-
16
-
-
2342484423
-
Structure of the BRCT repeats of BRCA1 bound to a BACH1 phosphopeptide: Implications for signaling
-
Shiozaki EN, Gu L, Yan N, Shi Y. Structure of the BRCT repeats of BRCA1 bound to a BACH1 phosphopeptide: implications for signaling. Mol Cell 2004;14:405-12.
-
(2004)
Mol Cell
, vol.14
, pp. 405-412
-
-
Shiozaki, E.N.1
Gu, L.2
Yan, N.3
Shi, Y.4
-
17
-
-
3142608985
-
Structural basis of BACH1 phosphopeptide recognition by BRCA1 tandem BRCT domains
-
Botuyan MV, Nomine Y, Yu X, et al. Structural basis of BACH1 phosphopeptide recognition by BRCA1 tandem BRCT domains. Structure (Camb) 2004;12:1137-46.
-
(2004)
Structure (Camb)
, vol.12
, pp. 1137-1146
-
-
Botuyan, M.V.1
Nomine, Y.2
Yu, X.3
-
18
-
-
0036500691
-
Structure of the 53BP1 BRCT region bound to p53 and its comparison to the Brca1 BRCT structure
-
Joo WS, Jeffrey PD, Cantor SB, Finnin MS, Livingston DM, Pavletich NP. Structure of the 53BP1 BRCT region bound to p53 and its comparison to the Brca1 BRCT structure. Genes Dev 2002;16:583-93.
-
(2002)
Genes Dev
, vol.16
, pp. 583-593
-
-
Joo, W.S.1
Jeffrey, P.D.2
Cantor, S.B.3
Finnin, M.S.4
Livingston, D.M.5
Pavletich, N.P.6
-
19
-
-
2542489188
-
Structure and mechanism of BRCA1 BRCT domain recognition of phosphorylated BACH1 with implications for cancer
-
Clapperton JA, Manke IA, Lowery DM, et al. Structure and mechanism of BRCA1 BRCT domain recognition of phosphorylated BACH1 with implications for cancer. Nat Struct Mol Biol 2004;11:512-8.
-
(2004)
Nat Struct Mol Biol
, vol.11
, pp. 512-518
-
-
Clapperton, J.A.1
Manke, I.A.2
Lowery, D.M.3
-
20
-
-
18544372595
-
BRCA2 function in DNA binding and recombination from a BRCA2-DSS1-ssDNA structure
-
Yang H, Jeffrey PD, Miller J, et al. BRCA2 function in DNA binding and recombination from a BRCA2-DSS1-ssDNA structure. Science 2002;297:1837-48.
-
(2002)
Science
, vol.297
, pp. 1837-1848
-
-
Yang, H.1
Jeffrey, P.D.2
Miller, J.3
-
21
-
-
0034804672
-
Structure of a BRCA1-BARD1 heterodimeric RING-RING complex
-
Brzovic PS, Rajagopal P, Hoyt DW, King MC, Klevit RE. Structure of a BRCA1-BARD1 heterodimeric RING-RING complex. Nat Struct Biol 2001;8:833-7.
-
(2001)
Nat Struct Biol
, vol.8
, pp. 833-837
-
-
Brzovic, P.S.1
Rajagopal, P.2
Hoyt, D.W.3
King, M.C.4
Klevit, R.E.5
-
22
-
-
7444267932
-
High-throughput computational and experimental techniques in structural genomics
-
Chance MR, Fiser A, Sali A, et al. High-throughput computational and experimental techniques in structural genomics. Genome Res 2004;14:2145-54.
-
(2004)
Genome Res
, vol.14
, pp. 2145-2154
-
-
Chance, M.R.1
Fiser, A.2
Sali, A.3
-
23
-
-
9644252804
-
Characterization of segments from the central region of BRCA1: An intrinsically disordered scaffold for multiple protein-protein and protein-DNA interactions?
-
Mark WY, Liao JC, Lu Y, et al. Characterization of segments from the central region of BRCA1: an intrinsically disordered scaffold for multiple protein-protein and protein-DNA interactions? J Mol Biol 2005;345:275-87.
-
(2005)
J Mol Biol
, vol.345
, pp. 275-287
-
-
Mark, W.Y.1
Liao, J.C.2
Lu, Y.3
-
24
-
-
2942755937
-
Purification and characterisation of a soluble N-terminal fragment of the breast cancer susceptibility protein BRCA1
-
Sturdy A, Naseem R, Webb M. Purification and characterisation of a soluble N-terminal fragment of the breast cancer susceptibility protein BRCA1. J Mol Biol 2004;340:469-75.
-
(2004)
J Mol Biol
, vol.340
, pp. 469-475
-
-
Sturdy, A.1
Naseem, R.2
Webb, M.3
-
25
-
-
33644537810
-
Comprehensive statistical study of 452 BRCA1 missense substitutions with classification of eight recurrent substitutions as neutral
-
In press
-
Tavtigian SV, Deffenbaugh AM, Yin L, et al. Comprehensive statistical study of 452 BRCA1 missense substitutions with classification of eight recurrent substitutions as neutral. J Med Genet. In press 2006.
-
(2006)
J Med Genet.
-
-
Tavtigian, S.V.1
Deffenbaugh, A.M.2
Yin, L.3
-
26
-
-
20844461337
-
LS-SNP: Largescale annotation of coding non-synonymous SNPs based on multiple information sources
-
Karchin R, Diekhans M, Kelly L, et al. LS-SNP: largescale annotation of coding non-synonymous SNPs based on multiple information sources. Bioinformatics 2005;21:2814-20.
-
(2005)
Bioinformatics
, vol.21
, pp. 2814-2820
-
-
Karchin, R.1
Diekhans, M.2
Kelly, L.3
-
27
-
-
0035869223
-
Prediction of deleterious human alleles
-
Sunyaev S, Ramensky V, Koch I, Lathe W III, Kondrashov AS, Bork P. Prediction of deleterious human alleles. Hum Mol Genet 2001;10:591-7.
-
(2001)
Hum Mol Genet
, vol.10
, pp. 591-597
-
-
Sunyaev, S.1
Ramensky, V.2
Koch, I.3
Lathe III, W.4
Kondrashov, A.S.5
Bork, P.6
-
28
-
-
0037432532
-
Structural location of disease-associated single-nucleotide polymorphisms
-
Stitziel NO, Tseng YY, Pervouchine D, Goddeau D, Kasif S, Liang J. Structural location of disease-associated single-nucleotide polymorphisms. J Mol Biol 2003;327:1021-30.
-
(2003)
J Mol Biol
, vol.327
, pp. 1021-1030
-
-
Stitziel, N.O.1
Tseng, Y.Y.2
Pervouchine, D.3
Goddeau, D.4
Kasif, S.5
Liang, J.6
-
29
-
-
2542543477
-
Structure-based assessment of missense mutations in human BRCA1: Implications for breast and ovarian cancer predisposition
-
Mirkovic N, Marti-Renom MA, Weber BL, Sali A, Monteiro AN. Structure-based assessment of missense mutations in human BRCA1: implications for breast and ovarian cancer predisposition. Cancer Res 2004;64:3790-7.
-
(2004)
Cancer Res
, vol.64
, pp. 3790-3797
-
-
Mirkovic, N.1
Marti-Renom, M.A.2
Weber, B.L.3
Sali, A.4
Monteiro, A.N.5
-
30
-
-
0025833314
-
Zeroing in on individual cancer risk
-
Marx J. Zeroing in on individual cancer risk. Science 1991;253:612-6.
-
(1991)
Science
, vol.253
, pp. 612-616
-
-
Marx, J.1
-
31
-
-
2342471392
-
Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib
-
Lynch TJ, Bell DW, Sordella R, et al. Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N Engl J Med 2004;350:2129-39.
-
(2004)
N Engl J Med
, vol.350
, pp. 2129-2139
-
-
Lynch, T.J.1
Bell, D.W.2
Sordella, R.3
-
32
-
-
7944238044
-
Somatic alterations in the human cancer genome
-
Weir B, Zhao X, Meyerson M. Somatic alterations in the human cancer genome. Cancer Cell 2004;6:433-8.
-
(2004)
Cancer Cell
, vol.6
, pp. 433-438
-
-
Weir, B.1
Zhao, X.2
Meyerson, M.3
|