Effect of the equipment configuration and operating conditions on process performance and on physical characteristics of the product during coating in spouted bed

Canadian Journal of Chemical Engineering

Volumn 82, Issue 1, 2004, Pages 122-133

  Publio, M C P ^a   Oliveira, W P ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Kinetics growth; Particle coating; Pharmaceutical process; Spouted beds

Indexed keywords

ADHESION; CHEMICAL ENGINEERING; COATINGS; GROWTH KINETICS; ORIFICES;

ADHESION COEFFICIENT; FEED FLOW RATE; MASS FLOW RATE; OPERATING CONDITIONS;

OPERATIONS RESEARCH;

PLACEBO;

COATING; PERFORMANCE ASSESSMENT; PHARMACEUTICAL INDUSTRY; SPOUTED BED;

ADHESION; CONFERENCE PAPER; CORRELATION COEFFICIENT; DRUG COATING; EQUIPMENT DESIGN; EVALUATION; FEEDING APPARATUS; FLOW KINETICS; FLOW RATE; FLUIDIZED BED; MATERIAL COATING; MATHEMATICAL PARAMETERS; NEBULIZATION; PROCESS DESIGN; PROCESS OPTIMIZATION; PRODUCT RECOVERY; SPOUTED BED; SUSPENSION; TABLET MATRIX; TABLET PROPERTY;

EID: 3342993334     PISSN: 00084034     EISSN: None     Source Type: Journal    
DOI: 10.1002/cjce.5450820116     Document Type: Conference Paper

References (51)

1. Bartoszewics, A., A. Kmiec and W. Ludwig, "Hydrodynamic Characteristics of a Spouted Bed Dryer With a Draft Tube", in "Proc. of 10th Intern. Drying Symp.", C. Strumillo and Z. Pakowski, Eds., Krakow, Poland, July 30 to Aug. 2, 1996, Drukarnia Papaj, Lódz, Poland (1996), pp. 417-426.
2. Bodmeier, R., "Coating of Solid Dosage Forms", Editorial, European J. Pharm. and Biopharm., 47, 1 (1999).
3. Choi, M. and A. Meisen, "Hydrodynamics of Shallow, Conical Spouted Beds", Can. J. Chem. Eng., 70, 916-924 (1992).
4. Choi, M. M. S and A. Meisen, "Sulfur Coating of Urea in Shallow Spouted Beds", Chem. Eng. Sci. 52, 1073-1086 (1997).
5. Colleta, V. and H. Rubin, "Wurster Coated Aspirin I", J. Pharm. Sci. 53, 953-955 (1964).
6. Conceiçao Filho, R. S., M. A. S. Barrozo, J. R. Limaverde and I. A. S. Castro, "Fertilizer Coating Over Soybeans Using the Spouted Bed", in "Proc. of the Inter-American Drying Conf. (IADC)", M. A. Silva and S. C. S. Rocha, Eds., Campinas, SP, Brazil, July 15-18, 1997, Gráfica Paes, Campinas, SP, Brazil (1997), pp. 487-494.
7. Dewettinck, K. and A. Huyghebaert, "Fluidized Bed Coating in Food Technology", Trends in Food Science and Technology, 10, 163-168 (1999).
8. Donita, M. W., "Recobrimento Polimérico de Uréia em Leito de cle Jorro Bidimensional", MSc Thesis, University of Campinas, Campinas, SP, Brazil (2000).
9. Duarte, C. R., "O Uso de Modelo de Balanço Populacional no Estudo de Inoculaçã de Sementes de Soja em Leito de Jorro", MSc Thesis, Federal University of Uberlândia, Uberlândia, MG, Brazil (2002).
10. Freitas, L. A. P. and J. T. Freire, "Development of a Spouted Bed Coater for Tablets", in "Proc. of II European Conference on Fluidization", M. Olazar, M. J. San José, Eds., Bilbao, Spain, Sept. 8-11, 1997, University of Basque Press Service, Bilbao, Spain (1997), pp. 363-369.
11. Friedman, M. and M. Donbrow "Fluidized-bed Coating Technique for Production of Sustained-release Granules", Drug Development and Industrial Pharmacy 4, 319-331 (1978).
12. Jose, M. J. S., M. Olazar, R. Aguado and J. Bilbao, "Influence of the Conical Section Geometry on the Hydrodynamics of Shallow Spouted Beds", Chem. Eng. J. and Biochemical Eng. Journal 62, 113-120 (1996).
13. Kmiec, A., "Hydrodynamics of Flows and Heat Transfer in Spouted Beds", Chem. Eng. J, 19, 189-200 (1980).
14. Kucharski, J. and A. Kmiec, "Hydrodynamics, Heat and Mass Transfer During Coating of Tablets in a Spouted Bed", Can. J. Chem. Eng. 61, 435-439 (1983).
15. Kucharski, J. and A. Kmiec, "Analysis of Simultaneous Drying and Coating of Tablets in a Spouted Bed", in "Proc. of the 5th Int. Drying Symp.", A. Mujumdar, Ed., Cambridge, MA, August 13-16, 1986, Hemisphere, Washington, U.S. (1986), pp. 204-217.
16. Kucharski, J. and A. Kmiec, "The Effect of Process Parameters on Mass Distributions and the Efficiency of Tablet Coating in a Spouted Bed", in "Proc. of the 6th Int. Drying Symp.", Versailles, France, September 5-8 (1988), pp. PA27-PA31.
17. Kucharski, J. and A. Kmiec, "Kinetics of Granulation Process During Coating of Tablets in a Spouted Bed", Chem. Eng. Sci. 44, 1627-1636 (1989).
18. Lachman, L. and J. Cooper, "A Programmed Automated Film-coating Process", J. Pharm. Sci. 52, 490-496 (1963).
19. Liu, L. X. and J. D. Litster, "Spouted Bed Seed Coating: The Effect of Process Variables on Maximum Coating Rate and Elutriation", Powder Tech. 74, 215-230 (1993a).
20. Liu, L. X. and J. D. Litster, "Coating Mass Distribution From a Spouted Bed Seed Coater: Experimental and Modelling Studies", Powder Tech. 74, 259-270 (1993b).
21. Mathur, K. B. and N. Epstein, "The Onset of Spouting", in "Spouted Beds", K. B. Mathur and N. Epstein, Eds., Academic Press, New York, NY (1974), pp. 14-46.
22. Mielczarski, S. and J. Kucharski, "Coating of Tablets in a Fluidized Bed System", Inz. Apar. Chem. 24, 13-17 (1985).
23. Oliveira W. P., "Contribuição ao Estudo do Processo de Revestimento de Partículas em Leito de Jorro", Associated Professor Thesis, Faculty of Pharmaceutical Sciences of Ribeirão Preto/University of Sao Paulo, Ribeirão Preto, SP, Brazil (2002).
24. Oliveira W. P., "Recobrimento de Partículas em Leito de Jorro", MSc Thesis, University Federal of São Carlos, São Carlos, SP, Brazil (1992).
25. Oliveira, W. P., J. T. Freire and J. R. Coury, "Analysis of Particle Coating by Spouted Bed Process", Int. J. Pharm. 158, 1-9 (1997).
26. Ormenese, A. A., "Granulaçã de Cloreto de Potássio em Leito Fluidizado", MSc Thesis, University Federal of São Carlos, São Carlos, SP, Brazil (1989).
27. Parikh, N. H., S. C. Porter, and B. D. Rohera, "Aqueous Ethylcellulose Dispersion of Ethyl-cellulose. I. Evaluation of Coating Process Variables", Pharm. Res., 10, 525-534 (1993).
28. Pavarini, P. J., "Granula̧ão de Rocha Fosfática em Leito de Jorro", MSc Thesis, University Federal of São Carlos, São Carlos, SP, Brazil (1987).
29. Pavarini, P. J. and J. R. Coury, "Granulation of an Insoluble Powder in a Spouted Bed", Powder Tech. 53, 97-103 (1987).
30. Porter, E. F., "Coat Seeds With Polymers", Chemtech, 8, 284-287 (1978).
31. Salman, O. A., "Polyethylene-Coated Urea. 1. Improves Storage and Handling Properties", Ind. Eng. Chem. Res. 28, 630-632 (1989).
32. Salman, O. A., G. Hovakeemian and N. Khraishi, "Polyethylene-Coated Urea 2. Urea Release as Affected by Coating Material, Soil Type and Temperature", Ind. Eng. Chem. Res. 28, 633-638 (1989).
33. Shasha, B. S., W. M. Doane and C. R. Russell, "Starch-Encapsulated Pesticides for Slow Release", J. Polym. Sci. Part C: Pol. Letters 14, 417-420 (1976).
34. Shirley, A. R. and R. S. Meline, "Sulphur-Coated Urea From a 1-ton-per-hour Pilot Plant", Adv Chem. Ser. 146, 33-54 (1975).
35. Silva, V. A., S. C. S. Rocha, O. P. Taranto, and G. S. V. Raghavan, "Analysis of the Stability of Spouted Bed Fluid Dynamic Regime Through Bed Pressure Drop Fluctuations Measurements", Sci. and Eng. J. 8, 129-137 (1999).
36. Silva, G. D., M. C. P. Publio, and W. P. Oliveira, "Evaluation of the Tablet Coating by the Conventional Spouted Bed Process", Drug Develop. and Ind. Pharm. 27, 213-219 (2001).
37. Singiser, R. E. and W. Lowenthal, "Enteric Filmcoats by the Air-Suspension Coating Technique", J. Pharm. Sci. 50, 168-170 (1961).
38. Taranto, O. P., S. C. S. Rocha and G. S. V. Raghavan, "Convective Heat Transfer During Coating of Particles in Two-Dimensional Spouted Beds", in "Proc. of 10th Intern. Drying Symp.", C. Strumillo and Z. Pakowski, Eds., Krakow, Poland, July 30-Aug. 2, 1996, Drukarnia Papaj, Lódz, Poland (1996), pp. 577-584.
39. Taranto, O. P., S. C. S. Rocha and G. S. V. Raghavan and G. E. Ayub, "Coating of Tablets With Polymeric Suspension in Two-Dimensional Spouted Beds, in "Proc. of the Inter-American Drying Conf. (IADC)", M. A. Silva and S. C. S. Rocha, Eds., Campinas, SP, Brazil, July 15-18, 1997, Gráfica Paes, Campinas, SP, Brazil (1997), pp. 272-279.
40. Türkoglu, M., M. He and A. Sakr, "Evaluation of Rotary Fluidized-Bed as a Wet Granulation Equipment", Eur. J. Pharm. Biopharm. 41, 388-394 (1995).
41. Türkoglu, M., W. A. Ritschel, and A. Sakr, "In Vivo Evaluation of Fluidized-Bed Coated Pellets", Int. J. Pharm. 103, 115-118 (1994).
42. Türkoglu, M. and A. Sakr, "Mathematical Modelling and Optimization of a Rotary Fluidized Bed Coating Process", Int. J. Pharm. 88, 75-87 (1992).
43. Watano, S., K. Yoshikawa and K. Miyanami, "Evaluation of Aqueous Enteric Coated Granules Prepared by Moisture Control Method in Tumbling Fluidized Bed Process", Chem. Pharm. Bull. 42, 663-667 (1994).
44. Weiss, P. J. and A. Meisen, "Laboratory Studies on Sulphur Coating Urea by the Spouted Bed Process", Can. J. Chem. Eng. 61, 440-447 (1983).
45. Wesdyk, R., Y. M. Joshi, J. Vincentis, A. W. Newman and N. B. Jain, "Factors Affecting Differences in Film Thickness of Beads Coated in Fluidized Bed Units", Int. J. Pharm. 93, 101-109 (1993).
46. Wurster, D. E., "Method of Applying Coatings to Tablets or the Like", U.S. Patent 2,648,609 (1953).
47. Wurster, D. E., "Method of Applying Coatings to Tablets or the Like", U.S. Patent 2,799,241 (1957).
48. Wurster, D. E. "Air-Suspension Technique of Coating Drug Particles-A Preliminary Report", J. American Pharm. Assoc. 48, 451-454 (1959).
49. Wurster, D. E. and J. A. Lindlof, "Particle Coating Apparatus", U.S. Patent 3,241,520 (1966).
50. Yang, T. S., G. V. Savage, J. Weiss and I. Ghebre-Sellassie, "The Effect of Spray Mode and Chamber Geometry of Fluid-Bed Coating Equipment and Other Parameters on an Aqueous-Based Ethylcellulose Coating", Int. J. Pharm. 86, 247-257 (1992).
51. Yeom, C. K., Y. H. Kim and J. M. Lee, "Microencapsulation of Water Soluble Herbicide by Interfacial Reaction. II. Release Properties of Microcapsules", J. Appl. Polym. Sci. 84, 1025-1034 (2002).