Improved cell growth and Taxol production of suspension-cultured Taxus chinensis var. mairei in alternating and direct current magnetic fields

Biotechnology Letters

Volumn 26, Issue 11, 2004, Pages 875-878

  Shang, Gui Min ^a   Wu, Jin Chuan ^a   Yuan, Ying Jin ^a  

^a TIANJIN UNIVERSITY   (China)

Author keywords

Growth; Magnetic field; Suspension culture; Taxol; Taxus chinensis var. mairei

Indexed keywords

PACLITAXEL;

ADAPTATION; ARTICLE; BIOSYNTHESIS; CELL CULTURE; CELL PROLIFERATION; CELL SURVIVAL; COMPARATIVE STUDY; CULTURE TECHNIQUE; ELECTROMAGNETIC FIELD; EVALUATION; METHODOLOGY; PHYSIOLOGY; RADIATION EXPOSURE; RADIATION RESPONSE; TAXUS;

ADAPTATION, PHYSIOLOGICAL; CELL CULTURE TECHNIQUES; CELL PROLIFERATION; CELL SURVIVAL; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, RADIATION; ELECTROMAGNETIC FIELDS; PACLITAXEL; TAXUS;

TAXUS; TAXUS CHINENSIS VAR. MAIREI;

EID: 3342956585     PISSN: 01415492     EISSN: None     Source Type: Journal    
DOI: 10.1023/B:bile.0000025895.76394.ab     Document Type: Article

References (10)

1. Fett-Neto AG, Zhang WY, DiCosmo F (1994) Kinetics of Taxol production, growth, and nutrient uptake in cell suspensions of Taxus caspidata. Biotechnol. Bioeng. 44: 205-210.
2. Gold S, Goodman R, Henderson AS (1994) Exposure of simian virus-40 transformed human cells to magnetic fields results in increased levels of T-antigen mRNA and protein. Bioelectromagnetics 15: 329-336.
3. Liburdy RP (1992) Calcium signaling in lymphocytes and ELF fields: evidence for an electric field metric and a site of interaction involving the calcium ion channel. FEBS Lett. 301: 53-59.
4. Lindström E, Lindström P, Berglund A, Lundgren E, Mild KH (1995) Intracellular calcium oscillations in a T-cell line after exposure to extremely-low-frequency magnetic fields with variable frequencies and flux denities. Bioelectromagnetics 16: 41-47.
5. Ryu DDY, Lee SO, Romani RJ (1990) Determination of growth rate for plant cell cultures: comparative studies. Biotechnol Bioeng. 35: 305-311.
6. Santini MT, Cametti C, Paradisi S, Straface E, Donelli G, Indovina PL, Malorni W (1995) 50 Hz sinusoidal magnetic field induces changes in the membrane electrical properties of K562 leukaemic cells. Bioelectrochem. Bioenerg. 36: 39-45.
7. Yang LN, Wang J, Cheng DW (1999) Research of the biophysical mechanisms for the effects of constant magnetic field treatment of wheat seeds. J. Southwest Agr. Uni. 21: 342-344.
8. Yuan YJ, Wei ZJ, Wu ZL, Wu JC (2001a) Improved Taxol production in suspension cultures of Taxus cuspidata var. mairei by in situ extraction combined with feeding and additional carbon source introduction in an airlift loop reactor. Biotechnol. Lett. 23: 1659-1662.
9. Yuan YJ, Li C, Hu ZD, Wu C (2001b) Signal transduction pathway for oxidative burst and Taxol production in suspension cultures of Taxus chinensis var. mairei induced by oligosaccharide from Fusarium oxysprum. Enzyme Microbiol. Technol. 9: 372-379.
10. 4+ in suspension cultures of Taxus cuspidata. J. Mol. Catal. B Enzym. 18: 251-260.