Biosensor based on Langmuir-Blodgett films of poly(3-hexyl thiophene) for detection of galactose in human blood

Biotechnology Letters

Volumn 26, Issue 8, 2004, Pages 645-647

  Sharma, Sandeep K ^a   Singhal, Rahul ^b   Malhotra, B D ^b   Sehgal, Neeta ^c   Kumar, Ashok ^a  

^a CSIR INSTITUTE OF GENOMICS AND INTEGRATIVE BIOLOGY   (India)

^b NATIONAL PHYSICAL LABORATORY   (India)

^c UNIVERSITY OF DELHI   (India)

Author keywords

Biosensor; Galactose; Galactosemia; Langmuir Blodgett films; Poly(3 hexyl thiophene)

Indexed keywords

BIOMATERIAL; GALACTOSE; IMMOBILIZED ENZYME; POLYMER; POLYTHIOPHENE; THIOPHENE DERIVATIVE;

ADULT; ARTICLE; BLOOD; CHEMISTRY; ELECTROCHEMISTRY; GENETIC PROCEDURES; HUMAN; METABOLISM; METHODOLOGY;

ADULT; BIOSENSING TECHNIQUES; COATED MATERIALS, BIOCOMPATIBLE; ELECTROCHEMISTRY; ENZYMES, IMMOBILIZED; GALACTOSE; HUMANS; POLYMERS; THIOPHENES;

EID: 3342928843     PISSN: 01415492     EISSN: None     Source Type: Journal    
DOI: 10.1023/B:BILE.0000023023.19651.01     Document Type: Article

References (12)

1. Croisetière LR, Rouillon R, Carpentier (2001) A simple mediatorless amperometric method using the cyanobacterium Synechococcus leopoliensis for the detection of phytotoxic pollutants. Appl. Microbiol. Biotechnol. 56: 261-264.
2. Hann RA (1990) Molecular structures and monolayer properties. In: Roberts G, ed. Langmuir-Blodgett Films. New York: Plenum, pp. 17-83.
3. Petry K, Reichardt J (1998) The fundamental importance of human galactose metabolism: lessons from genetics and biochemistry. Trends Genet. 14: 98-102.
4. Petty MC (1991) Application of multiplayer films to molecular sensors: some examples of bioengineering at the molecular level. J. Biomed. Eng. 13: 209-214.
5. Rajendran V, Lrudayaraj J (2002) Detection of glucose, galactose and lactose in milk with a microdialysis-coupled flow injection amperometric sensor. J. Daily Sci. 85: 1357-1361.
6. Schumacher D, Vogel J, Lerde LI (1994) Construction and application of enzyme electrode for determination of galactose and galactose containing saccharides. Biosens. Bioelectron. 9: 85-90.
7. Segal S (2001) In vivo evidence of brain galactitol accumulation in an infant with galactosemia and encephalopathy. J. Pediat. 138: 260-262.
8. 13C galactose by lymphoblasts from patients with galactosemia determined by NMR spectroscopy. Mol. Genet. Metabol. 77: 296-303.
9. Szabo EE, Adanyi N, Varadi M (1996) Application of biosensor for monitoring galactose content. Biosens. Bioelectron. 11: 1051-1058.
10. Watanbe N, Kawasaki S (1987) Determination of galactose in human plasma by HPLC with electrochemical detection. Biomed. Chromatogr. 2: 95-98.
11. Wilkins JR (1978) Use of platinum electrodes for the electrochemical detection of bacteria. Appl. Env. Microbiol. 36: 683-687.
12. Worthington V (1972) Worthington Enzyme Manual. Freehold, NJ: Worthington Biochemical Corporation, pp. 21-22.